■新兴文献表明,童年创伤可能会影响面部情绪感知(FEP),有可能对情绪感知和对情绪相关输入的反应产生负面影响。负面情绪感知偏差与一系列精神和行为问题有关,可能是由于困难的社交互动造成的。不幸的是,对于观察到的负面偏见是否与儿童创伤史有关,抑郁症史,或两种经验共同的过程(和潜在的因果关系)。
■本横断面研究检查了FEP与FEP期间神经激活之间的关系,并回顾性报道了患有缓解的重度抑郁症的年轻成年参与者的童年创伤(rMDD,n=41)且无精神病史(健康对照[HC],n=34)。在暴露于恐惧,生气,快乐,悲伤,中立的面孔。我们检查了参与者的行为和神经反应与儿童虐待和忽视的总报告严重程度的关系(用儿童创伤问卷评估,CTQ)。
■多重比较校正的结果表明,较高的创伤评分与将快乐面孔错误分类为生气的可能性更大有关。当参与者看到他们正确归类为愤怒的面孔时,右额中回(MFG)的激活与创伤评分呈正相关。恐惧,悲伤,和快乐。
■确定童年创伤和MDD可能改变面部情绪感知的神经机制可以为MDD或相关人际关系困难的有针对性的预防工作提供依据。
UNASSIGNED: Emerging literature suggests that childhood trauma may influence facial emotion perception (FEP), with the potential to negatively bias both emotion perception and reactions to emotion-related inputs. Negative emotion perception biases are associated with a range of psychiatric and behavioral problems, potentially due or as a result of difficult social interactions. Unfortunately, there is a poor understanding of whether observed negative biases are related to childhood trauma history, depression history, or processes common to (and potentially causative of) both experiences.
UNASSIGNED: The present cross-sectional study examines the relation between FEP and neural activation during FEP with retrospectively reported childhood trauma in young adult participants with remitted major depressive disorder (rMDD, n = 41) and without psychiatric histories (healthy controls [HC], n = 34). Accuracy of emotion categorization and negative bias errors during FEP and brain activation were each measured during exposure to fearful, angry, happy, sad, and neutral faces. We examined participant behavioral and neural responses in relation to total reported severity of childhood abuse and neglect (assessed with the Childhood Trauma Questionnaire, CTQ).
UNASSIGNED: Results corrected for multiple comparisons indicate that higher trauma scores were associated with greater likelihood of miscategorizing happy faces as angry. Activation in the right middle frontal gyrus (MFG) positively correlated with trauma scores when participants viewed faces that they correctly categorized as angry, fearful, sad, and happy.
UNASSIGNED: Identifying the neural mechanisms by which childhood trauma and MDD may change facial emotion perception could inform targeted prevention efforts for MDD or related interpersonal difficulties.