背景:在多发性硬化症(MS)的早期阶段,没有客观敏感的功能评估来识别和量化复杂运动过程中的早期亚临床神经肌肉缺陷和下肢力量不对称。单反运动跳跃(SLCMJ),最大单腿垂直跳跃,在力板上允许在性能诊断中对单侧下肢性能进行功能评估,因此可以提供MS不对称的早期结果。
目的:使用SLCMJ在力板上客观评估多发性硬化症(pwMS)患者的早期下肢神经肌肉缺陷和不对称性。
方法:使用pwMS(N=126)和健康对照(N=97)进行研究。所有参与者在测力板上进行了3次最大SLCMJ。时间,动力学,并采集了功率跳变参数。对所有参与者进行扩展残疾状态量表(EDSS)。随年龄的重复测量协方差分析(ANCOVA),身体质量指数,使用性别作为协变量。
结果:根据手动肌肉测试,具有正常肌肉力量的PwMS显示与HC相比,SLCMJ性能显着降低。在这两组中,优势腿和非优势腿之间的跳跃性能差异显着,对于pwMS具有更高的效果大小。在推进时间上发现了腿部优势与群体之间的显着交互作用,与HC相比,pwMS在优势腿和非优势腿之间显示出更高的差异。此外,pwMS中腿部不对称与EDSS之间存在显著的小相关性。
结论:研究表明,力板上的SLCMJ适用于MS的亚临床下肢神经肌肉缺陷和力量不对称的早期检测。
BACKGROUND: In the early stages of multiple sclerosis (MS), there are no objective sensitive functional assessments to identify and quantify early subclinical neuromuscular deficits and lower limb strength asymmetries during complex movements. Single-countermovement jumps (SLCMJ), a maximum single leg vertical jump, on a force plate allow functional evaluation of unilateral lower limb performance in performance diagnostics and could therefore provide early results on asymmetries in MS.
OBJECTIVE: Objective evaluation of early lower limb neuromuscular deficits and asymmetries in people with multiple sclerosis (pwMS) using SLCMJ on a force plate.
METHODS: A study was conducted with pwMS (N = 126) and healthy controls (N = 97). All participants performed 3 maximal SLCMJs on a force plate. Temporal, kinetic, and power jump parameters were collected. The Expanded Disability Status Scale (EDSS) was performed on all participants. A repeated measures analysis of covariance (ANCOVA) with age, Body-Mass-Index, and gender as covariates was used.
RESULTS: PwMS with normal muscle strength according to the manual muscle tests showed significantly reduced SLCMJ performance compared to HC. In both groups, jumping performance differed significantly between the dominant and non-dominant leg, with higher effect size for pwMS. A significant interaction effect between leg dominance and group was found for propulsive time, where the pwMS showed an even higher difference between the dominant and non-dominant leg compared to HC. Furthermore, there was a significant small correlation between leg asymmetries and EDSS in pwMS.
CONCLUSIONS: The study shows that the SLCMJ on a force plate is suitable for the early detection of subclinical lower limb neuromuscular deficits and strength asymmetries in MS.