PDF(Pubmed)
Abstract：
(1) Background: The countermovement jump (CMJ) on a force plate could be a sensitive assessment for detecting early lower-limb muscle mechanical deficits in the early stages of multiple sclerosis (MS). CMJ performance is known to be influenced by various anthropometric, physiological, and biomechanical factors, mostly investigated in children and adult athletes. Our aim was to investigate the association of age, sex, and BMI with muscle mechanical function using CMJ to provide a comprehensive overview of lower-limb motor function in people with multiple sclerosis (pwMS). (2) Methods: A cross-sectional study was conducted with pwMS (N = 164) and healthy controls (N = 98). All participants performed three maximal CMJs on a force plate. Age, sex, and BMI were collected from all participants. (3) Results: Significant age, sex, and BMI effects were found for all performance parameters, flight time, and negative and positive power for pwMS and HC, but no significant interaction effects with the group (pwMS, HC) were detected. The highest significant effects were found for sex on flight time (η2 = 0.23), jump height (η2 = 0.23), and positive power (η2 = 0.13). PwMS showed significantly lower CMJ performance compared to HC in middle-aged (31-49 years), with normal weight to overweight and in both women and men. (4) Conclusions: This study showed that age, sex, and BMI are associated with muscle mechanical function in pwMS and HC. These results may be useful in developing reference values for CMJ. This is a crucial step in integrating CMJ into the diagnostic assessment of people with early MS and developing individualized and effective neurorehabilitative therapy.
摘要：
（1）背景：力板上的反运动跳跃（CMJ）可能是检测多发性硬化症（MS）早期下肢肌肉机械缺陷的敏感评估。已知CMJ性能受各种人体测量的影响，生理,和生物力学因素，主要调查儿童和成年运动员。我们的目的是调查年龄的关联，性别,和BMI与肌肉机械功能使用CMJ提供了多发性硬化症（pwMS）患者下肢运动功能的全面概述。(2)方法:采用pwMS(N=164)和健康对照(N=98)进行横断面研究。所有参与者在一个力板上执行了三个最大CMJ。年龄,性别,从所有参与者中收集BMI。（3）结果：显著年龄，性别,并且发现了所有性能参数的BMI效应，飞行时间,pwMS和HC的正负功率，但与该组没有显著的交互作用(pwMS，HC）被检测到。性别对飞行时间的影响最高(η2=0.23)，跳跃高度(η2=0.23)，和正功率(η2=0.13)。与中年（31-49岁）的HC相比，PwMS显示出CMJ性能显着降低，正常体重超重，女性和男性。(4)结论:本研究表明,年龄,性别,BMI与pwMS和HC的肌肉机械功能有关。这些结果可能有助于开发CMJ的参考值。这是将CMJ纳入早期MS患者的诊断评估和开发个性化有效的神经康复治疗的关键步骤。
