low cost

低成本
  • 文章类型: Journal Article
    振动传感器广泛应用于工业等诸多领域,农业,军事,医学,环境,等。然而,由于快速升级,大多数由刚性甚至有毒材料组成的传感器会对环境造成污染,并导致电子废物的数量增加。为了满足绿色电子的要求,提倡使用可生物降解材料来开发振动传感器。在这里,据报道,振动传感器是基于铅笔在纸上绘制石墨的策略。具体来说,在具有锯齿形框架和平行微槽的纸上进行重复的铅笔绘图过程,形成石墨涂层,因此用作用于机电信号转换的功能导电层。为了提高传感器对振动的灵敏度,在纸的中心加载了一个质量,因此,在振动激励下可能会发生更高的振荡幅度。这样做,基于纸张的传感器可以响应从5Hz到1kHz的宽频率范围的振动,和最大加速度为10g的振动。结果表明,该传感器不仅可以用于监测塑料板或物体掉落的转向节敲击声产生的振动,而且可以用于检测诸如屏蔽切割头之类的区域的振动,以评估机械的工作条件。基于纸的MEMS振动传感器具有易于制造的优点,低成本,环保,表明了其在振动监测领域的巨大应用潜力。
    Vibration sensors are widely used in many fields like industry, agriculture, military, medicine, environment, etc. However, due to the speedy upgrading, most sensors composed of rigid or even toxic materials cause pollution to the environment and give rise to an increased amount of electronic waste. To meet the requirement of green electronics, biodegradable materials are advocated to be used to develop vibration sensors. Herein, a vibration sensor is reported based on a strategy of pencil-drawing graphite on paper. Specifically, a repeated pencil-drawing process is carried out on paper with a zigzag-shaped framework and parallel microgrooves, to form a graphite coating, thus serving as a functional conductive layer for electromechanical signal conversion. To enhance the sensor\'s sensitivity to vibration, a mass is loaded in the center of the paper, so that higher oscillation amplitude could happen under vibrational excitation. In so doing, the paper-based sensor can respond to vibrations with a wide frequency range from 5 Hz to 1 kHz, and vibrations with a maximum acceleration of 10 g. The results demonstrate that the sensor can not only be utilized for monitoring vibrations generated by the knuckle-knocking of plastic plates or objects falling down but also can be used to detect vibration in areas such as the shield cut head to assess the working conditions of machinery. The paper-based MEMS vibration sensor exhibits merits like easy fabrication, low cost, and being environmentally friendly, which indicates its great application potential in vibration monitoring fields.
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  • 文章类型: Journal Article
    本文提出了一种模块化的无源全金属透镜,以实现可调焦距的近场聚焦。提议的透镜由全金属单元组成,相位覆盖范围超过360°,单元的布置由相位补偿法指导。具体来说,使用模块单元合成的策略,不同焦距下的透镜单元的布置可以任意组装,降低了39.3%的生产成本,提高了镜头设计的自由度。仿真和实验结果表明,该透镜表现出优异的聚焦特性,并自由改变预期焦点的位置(0.30m-0.75m)。因此,本文设计的模块化全金属透镜具有高透明度和高自由度的特点,它可以为天线领域的各种应用提供低成本和轻量级的解决方案,例如近场目标检测,微波成像,生物医学,等等。
    This article proposes a modular and passive all-metal lens to achieve near-field focusing with adjustable focus. The proposed lens consists of all-metal units with the phase coverage range exceeding 360°, and the arrangement of units is guided by the phase compensation method. Specifically, using the strategy of module unit synthesis, the arrangement of lens units under different focuses can be assembled arbitrarily, which reduces the production costs by 39.3% and improves the freedom of lens design. The simulation and experimental results show that the lens exhibits excellent focusing properties and freely changes the position of the expected focus (0.30 m-0.75 m). Therefore, the modular all-metal lens designed in this article has the characteristics of high transparency and a high degree of freedom, which can provide low-cost and lightweight solutions for various applications in the field of antennas, such as near-field target detection, microwave imaging, biomedicine, and so on.
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  • 文章类型: Journal Article
    目的:评估乳腺特异性伽玛成像(BSGI)作为活检减少问题解决策略的临床表现和财务成本,用于诊断影像学结果不确定的患者。
    方法:在2013年1月至2018年12月期间,对所有使用BSGI的患者进行了回顾性分析,以进行完整的诊断性乳房X线摄影和超声检查评估后的影像学检查。BSGI阳性发现与US或立体定向技术相关并进行活检,并通过夹子位置和病理学进行确认。BSGI阴性结果后,对患者随访至少24个月或认为失访并排除(22例).进一步成像研究的结果,活检,并对病理结果进行分析。避免活检的净节省是根据平均医疗保险费用计算的。
    结果:我们的研究包括40名30至95岁(平均55岁)的女性患者。BSGI显示阴性预测值(NPV)为98.4%(314/319),活检的阳性预测值为35.5%(43/121)。总体灵敏度为89.6%(43/48),特异性为80.1%(314/392)。总的来说,鉴定了78个假阳性,但只有5个假阴性的BSGI发现。用BSGI分析了6121个不确定的成像发现,总共避免了309个活检。避免活检的估计净财务节省为$646897。
    结论:在乳腺摄影或超声检查影像学检查结果不确定的患者的治疗中,BSGI是一种具有高NPV的解决问题的成像模式,有助于避免图像引导活检的成本。
    OBJECTIVE: To evaluate the clinical performance and financial costs of breast-specific gamma imaging (BSGI) as a biopsy-reducing problem-solving strategy in patients with inconclusive diagnostic imaging findings.
    METHODS: A retrospective analysis of all patients for whom BSGI was utilized for inconclusive imaging findings following complete diagnostic mammographic and sonographic evaluation between January 2013 and December 2018 was performed. Positive BSGI findings were correlated and biopsied with either US or stereotactic technique with confirmation by clip location and pathology. After a negative BSGI result, patients were followed for a minimum of 24 months or considered lost to follow-up and excluded (22 patients). Results of further imaging studies, biopsies, and pathology results were analyzed. Net savings of avoided biopsies were calculated based on average Medicare charges.
    RESULTS: Four hundred and forty female patients from 30 to 95 years (mean 55 years) of age were included in our study. BSGI demonstrated a negative predictive value (NPV) of 98.4% (314/319) and a positive predictive value for biopsy of 35.5% (43/121). The overall sensitivity was 89.6% (43/48), and the specificity was 80.1% (314/392). In total, 78 false positive but only 5 false negative BSGI findings were identified. Six hundred and twenty-one inconclusive imaging findings were analyzed with BSGI and a total of 309 biopsies were avoided. Estimated net financial savings from avoided biopsies were $646 897.
    CONCLUSIONS: In the management of patients with inconclusive imaging findings on mammography or ultrasonography, BSGI is a problem-solving imaging modality with high NPV that helps avoid costs of image-guided biopsies.
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  • 文章类型: Journal Article
    在COVID-19大流行导致的封锁期间继续睡眠研究活动,以前在实验室进行的实验被转移到志愿者的家中。此外,为了广泛的数据收集,有必要使用大量的便携式设备。因此,为了实现这些目标,我们开发了一种低成本且开源的便携式监护仪(PM)设备,能够使用流行的ESP32微控制器获取脑电图(EEG)信号。该器件基于仪表放大器工作。它还具有带Wi-Fi和蓝牙的连接微控制器,可用于流式传输EEG信号。这种便携式单通道三电极脑电图设备使我们能够记录小睡时间并对不同的睡眠阶段进行评分,比如觉醒,非快速眼动睡眠(NREM),阶段1(S1),阶段2(S2),阶段3(S3)和阶段4(S4)。我们通过将获得的信号与研究级信号产生的信号进行比较来验证该设备。结果显示两个设备之间的高度准确的相似性,证明了使用这种方法进行广泛且低成本的EEG睡眠记录数据收集的可行性。
    To continue sleep research activities during the lockdown resulting from the COVID-19 pandemic, experiments that were previously conducted in laboratories were shifted to the homes of volunteers. Furthermore, for extensive data collection, it is necessary to use a large number of portable devices. Hence, to achieve these objectives, we developed a low-cost and open-source portable monitor (PM) device capable of acquiring electroencephalographic (EEG) signals using the popular ESP32 microcontroller. The device operates based on instrumentation amplifiers. It also has a connectivity microcontroller with Wi-Fi and Bluetooth that can be used to stream EEG signals. This portable single-channel 3-electrode EEG device allowed us to record short naps and score different sleep stages, such as wakefulness, non rapid eye movement sleep (NREM), stage 1 (S1), stage 2 (S2), stage 3 (S3) and stage 4 (S4). We validated the device by comparing the obtained signals to those generated by a research-grade counterpart. The results showed a high level of accurate similarity between both devices, demonstrating the feasibility of using this approach for extensive and low-cost data collection of EEG sleep recordings.
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  • 文章类型: Journal Article
    许多先进的技术已被用于高性能有源矩阵显示器,包括液晶显示器,有机发光二极管显示器,和微型发光二极管显示器。在另一边,对降低成本有强烈的需求,这是基于薄膜晶体管技术将驱动电路集成到面板中的低成本方案之一。本文回顾了总体概念,操作原则,以及用于产生扫描脉冲的移位寄存器中的各种电路方法。此外,它涉及在栅极驱动器中实现附加功能以支持像素补偿,多线驱动,内嵌式电容式触摸屏,像素感测,和自适应扫描区域控制。
    Many advanced technologies have been employed in high-performance active matrix displays, including liquid crystal displays, organic light-emitting diode displays, and micro-light-emitting diode displays. On the other side, there exists a strong demand for cost reduction, and it is one of the low-cost schemes for integrating the driver circuit in a panel based on thin-film transistor technologies. This paper reviews the overall concept, operation principles, and various circuit approaches in shift registers for scanning pulse generation. In addition, it deals with the implementation of additional functionalities in gate drivers to support pixel compensation, multi-line driving, in-cell capacitive touch screen, pixel sensing, and adaptive scanning region control.
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  • 文章类型: Journal Article
    目的:T1标测和T1加权对比在胎儿MRI中具有互补但目前尚未被利用的作用。新兴的临床低场扫描仪非常适合胎儿T1标测。优点是较低的T1值,这导致更高的效率和减少的场不均匀性,从而降低了对专用工具的需求。此外,与低场扫描仪相关联的增加的孔尺寸提供了改善的患者舒适度和可接近性。本研究旨在证明胎儿脑T1标测在0.55T的可行性。
    方法:在一组38例胎儿MRI扫描中,在0.55T的胎儿大脑中,证明了一种有效的基于切片混洗反转恢复回波平面成像(EPI)的T1映射和后处理。进行稳健性分析,并进行胎盘测量以进行验证。
    结果:获得了高质量的T1图,可以对大脑中的子区域进行调查,并证明了胎儿大脑T1图与胎龄的显着相关性(p<0。05$$p<0.05$$)以及深灰质和白质中的感兴趣区域。
    结论:高效,在临床0.55TMRI扫描仪上证明了胎儿大脑中的定量T1映射,为未来的研究和临床应用提供基础,包括低领域特定的T1加权收购。
    OBJECTIVE: T1 mapping and T1-weighted contrasts have a complimentary but currently under utilized role in fetal MRI. Emerging clinical low field scanners are ideally suited for fetal T1 mapping. The advantages are lower T1 values which results in higher efficiency and reduced field inhomogeneities resulting in a decreased requirement for specialist tools. In addition the increased bore size associated with low field scanners provides improved patient comfort and accessibility. This study aims to demonstrate the feasibility of fetal brain T1 mapping at 0.55T.
    METHODS: An efficient slice-shuffling inversion-recovery echo-planar imaging (EPI)-based T1-mapping and postprocessing was demonstrated for the fetal brain at 0.55T in a cohort of 38 fetal MRI scans. Robustness analysis was performed and placental measurements were taken for validation.
    RESULTS: High-quality T1 maps allowing the investigation of subregions in the brain were obtained and significant correlation with gestational age was demonstrated for fetal brain T1 maps ( p < 0 . 05 $$ p<0.05 $$ ) as well as regions-of-interest in the deep gray matter and white matter.
    CONCLUSIONS: Efficient, quantitative T1 mapping in the fetal brain was demonstrated on a clinical 0.55T MRI scanner, providing foundations for both future research and clinical applications including low-field specific T1-weighted acquisitions.
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  • 文章类型: Journal Article
    已经提出了用于桥梁结构健康监测的各种方法。提出的最早的方法之一是随着时间的推移跟踪桥梁的固有频率,以寻找可能表明刚度变化的频率异常变化。然而,桥的频率随着结构温度的变化而自然变化。通过预测结构固有频率的正常变化并将其与桥梁的历史正常行为进行比较,可以使用数据模型来克服此问题,因此,识别异常行为。大多数拟议的数据建模工作都来自大跨度桥梁,您通常需要使用大型数据集。在数据量很少的地方进行了更有限的研究,但即使这也只在单桥上得到了证明。因此,这项工作的新颖之处在于,它在桥梁网络中使用稀疏的仪器扩展了以前的工作。从四个运营中的桥梁收集的数据用于验证数据模型并测试跨一系列桥梁类型/大小的数据模型的能力。发现MID方法能够在所有数据模型上检测0.021Hz的平均频移。此演示跨不同桥梁类型的意义在于,这些数据模型将在整个桥梁网络中使用,能够在桥梁维护和管理中做出准确和明智的决策。
    Various approaches have been proposed for bridge structural health monitoring. One of the earliest approaches proposed was tracking a bridge\'s natural frequency over time to look for abnormal shifts in frequency that might indicate a change in stiffness. However, bridge frequencies change naturally as the structure\'s temperature changes. Data models can be used to overcome this problem by predicting normal changes to a structure\'s natural frequency and comparing it to the historical normal behaviour of the bridge and, therefore, identifying abnormal behaviour. Most of the proposed data modelling work has been from long-span bridges where you generally have large datasets to work with. A more limited body of research has been conducted where there is a sparse amount of data, but even this has only been demonstrated on single bridges. Therefore, the novelty of this work is that it expands on previous work using sparse instrumentation across a network of bridges. The data collected from four in-operation bridges were used to validate data models and test the capabilities of the data models across a range of bridge types/sizes. The MID approach was found to be able to detect an average frequency shift of 0.021 Hz across all of the data models. The significance of this demonstration across different bridge types is the practical utility of these data models to be used across entire bridge networks, enabling accurate and informed decision making in bridge maintenance and management.
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  • 文章类型: Journal Article
    荧光相关实验技术在生物化学中起着重要作用,分子生物学,和细胞生物学。然而,与荧光相关的实验很少包含在大多数中国大学的实验室课程中。这主要是由于大型班级规模(一个房间中有50-60名学生)与购买和容纳足够的荧光检测设备的资金/空间限制之间的冲突。这里,我们提出了一种手持式荧光检测器集-荧光检测器的可行且经济的自己动手(DIY)程序,以支持实验室课程的开发。对几个样品进行了测试,清晰的荧光信号可以直接观察到荧光探测器和智能手机拍摄。此外,荧光探测器能够将传统的立体显微镜变成荧光立体显微镜,用干净的背景检测荧光信号。荧光探测器很容易用3D打印机制作,与商用荧光显微镜或荧光立体显微镜相比,成本极低(每个200美元),在测量荧光方面几乎和酶标仪一样灵敏。因此,荧光检测器是解决问题的一种可能策略,并有助于在实验室课程中集成与荧光相关的实验模块。
    Fluorescence-related experimental techniques play an important role in biochemistry, molecular biology, and cell biology. However, fluorescence-related experiments are rarely included in the laboratory courses of most Chinese universities. This is mainly due to the conflict between large class size (50-60 students in one room) and funding/space limitations to purchase and accommodate enough fluorescence detection equipment. Here, we proposed feasible and economical Do It Yourself (DIY) procedures of a hand-held fluorescence detector set-FluorDetector to support the development of laboratory courses. Tested on several samples, clear fluorescence signals could be directly observed by FluorDetector and photographed with a smartphone. In addition, FluorDetector was able to turn a conventional stereomicroscope into a fluorescence stereomicroscope, detecting fluorescence signals with clean background. FluorDetector is easy to make with a 3D printer, with an extremely low cost ($200 each) when compared with a commercial fluorescence microscope or fluorescence stereomicroscope, and almost as sensitive as a microplate reader in measuring fluorescence. Therefore, FluorDetector is a possible strategy to solve the problem and help to integrate fluorescence-related experimental modules in laboratory courses.
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  • 文章类型: Journal Article
    双极化可编程超表面可以灵活地操纵电磁(EM)波,同时提供大约两倍的信息容量。因此,它们在下一代通信系统中具有重要的应用。然而,存在与现有的双极化可编程超表面相关的三个挑战。本文旨在提出一种新颖的设计来解决这些问题。首先,该设计克服了独立于元素和偏振控制的挑战,使EM波的更强大的操纵。第二,通过使用更节能的可调谐组件并减少其数量,该设计几乎是无源的(最大功耗为27.7mW),导致系统的成本和功耗显着降低(比常规可编程超表面的功耗低至少两个数量级)。第三,该设计可以在宽的带宽下运行,这对实际工程应用很有吸引力。超表面的元素和阵列都经过精心设计,他们的表现已经被仔细研究过。实验表明,可以实现二维广角光束扫描。此外,基于方向信息调制的安全通信可以通过利用超表面和有效的离散优化算法来实现,显示其可编程,多路复用,宽带,绿色,和安全的功能。
    Dual-polarization programmable metasurfaces can flexibly manipulate electromagnetic (EM) waves while providing approximately twice the information capacity. Therefore, they hold significant applications in next-generation communication systems. However, there are three challenges associated with the existing dual-polarization programmable metasurfaces. This article aims to propose a novel design to address them. First, the design overcomes the challenge of element- and polarization-independent controls, enabling more powerful manipulations of EM waves. Second, by using more energy-efficient tunable components and reducing their number, the design can be nearly passive (maximum power consumption of 27.7 mW), leading to a significant decrease in the cost and power consumption of the system (at least two orders of magnitude lower than the power consumption of conventional programmable metasurfaces). Third, the design can operate in a broad bandwidth, which is attractive for practical engineering applications. Both the element and array of the metasurface are meticulously designed, and their performance has been carefully studied. The experiments demonstrate that 2D wide-angle beam scanning can be realized. Moreover, secure communication based on directional information modulation can be implemented by exploiting the metasurface and an efficient discrete optimization algorithm, showing its programmable, multiplexing, broadband, green, and secure features.
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  • 文章类型: Journal Article
    面对不断增长的人口,不稳定的气候,资源枯竭,增加了对自然灾害的接触,环境监测越来越重要。卫星数据构成了我们对地球的大部分观测。基于原位传感器系统的地面观测对于这些远程测量的可靠性至关重要。为环境数据记录系统的快速原型提供开源选项,可以快速推进研究和监控程序。本文介绍了织机,低功耗Arduino可编程微控制器的开发环境。织机可容纳一系列集成组件,包括传感器,各种数据记录格式,互联网连接(包括Wi-Fi和4G长期演进(LTE)),无线电遥测,定时机制,调试信息,和节能功能。此外,织机包括科学的独特应用,技术,工程,数学(STEM)教育。通过建立模块化,可重构,和跨组件的可扩展功能,织机减少了新系统原型的开发时间。在一个项目中实现的错误修复和优化使所有使用织机的项目受益,提高效率。虽然不是一刀切的解决方案,这种方法使一小部分开发人员能够支持大型多学科团队为水设计各种环境传感应用程序,土壤,大气,农业,环境危害,科学监测,和教育。本文不仅概述了系统设计,还讨论了在织机开发中探索的替代方法和关键决策点。
    In the face of rising population, erratic climate, resource depletion, and increased exposure to natural hazards, environmental monitoring is increasingly important. Satellite data form most of our observations of Earth. On-the-ground observations based on in situ sensor systems are crucial for these remote measurements to be dependable. Providing open-source options to rapidly prototype environmental datalogging systems allows quick advancement of research and monitoring programs. This paper introduces Loom, a development environment for low-power Arduino-programmable microcontrollers. Loom accommodates a range of integrated components including sensors, various datalogging formats, internet connectivity (including Wi-Fi and 4G Long Term Evolution (LTE)), radio telemetry, timing mechanisms, debugging information, and power conservation functions. Additionally, Loom includes unique applications for science, technology, engineering, and mathematics (STEM) education. By establishing modular, reconfigurable, and extensible functionality across components, Loom reduces development time for prototyping new systems. Bug fixes and optimizations achieved in one project benefit all projects that use Loom, enhancing efficiency. Although not a one-size-fits-all solution, this approach has empowered a small group of developers to support larger multidisciplinary teams designing diverse environmental sensing applications for water, soil, atmosphere, agriculture, environmental hazards, scientific monitoring, and education. This paper not only outlines the system design but also discusses alternative approaches explored and key decision points in Loom\'s development.
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