目的:意大利汽车与运动科学学会(SocietàItalianadiScienzeMotorieeSportive,SISMeS)和意大利人口学学会(SocietàItalianadiFlebologia,SIF)提供了关于运动作为非药理学方法在脂水肿中的作用的官方观点。详细来说,这份共识声明SISMeS-SIF旨在全面概述lipedema,聚焦,特别是,关于体育锻炼(PE)在其临床特征管理中的作用。
结果:脂肪水肿是一种以脂肪积累异常为特征的慢性疾病。常被误诊为肥胖,尽管呈现出不同的病理机制。的确,最近的证据报道了脂肪组织组织学的差异,代谢组学概况,以及与这种情况相关的基因多态性,为复杂的脂水肿病理生理学难题增加新的部分。虽然根据定义,脂水肿是一种对饮食和PE有抵抗力的疾病,后者因其在脂脉管理中的关键作用而出现,为多种福利做出贡献,包括线粒体功能的改善,淋巴引流,减少炎症。各种类型的运动,例如水上运动和力量训练,已被证明可以缓解症状并改善患者的生活质量。然而,缺乏PE处方和脂肪水肿患者长期管理的标准化指南,强调需要在这一领域提出建议和进一步研究,以优化治疗策略。
OBJECTIVE: This consensus statement from the Italian Society of Motor and Sports Sciences (Società Italiana di Scienze Motorie e Sportive, SISMeS) and the Italian Society of Phlebology (Società Italiana di Flebologia, SIF) provides the official view on the role of exercise as a non-pharmacological approach in
lipedema. In detail, this consensus statement SISMeS - SIF aims to provide a comprehensive overview of
lipedema, focusing, in particular, on the role played by physical exercise (PE) in the management of its clinical features.
RESULTS: Lipedema is a chronic disease characterized by abnormal fat accumulation. It is often misdiagnosed as obesity, despite presenting distinct pathological mechanisms. Indeed, recent evidence has reported differences in adipose tissue histology, metabolomic profiles, and gene polymorphisms associated with this condition, adding new pieces to the complex puzzle of lipedema pathophysiology. Although by definition
lipedema is a condition resistant to diet and PE, the latter emerges for its key role in the management of lipedema, contributing to multiple benefits, including improvements in mitochondrial function, lymphatic drainage, and reduction of inflammation. Various types of exercise, such as aquatic exercises and strength training, have been shown to alleviate symptoms and improve the quality of life of patients with lipedema. However, standardized guidelines for PE prescription and long-term management of patients with
lipedema are lacking, highlighting the need for recommendations and further research in this area in order to optimise therapeutic strategies.