intradural tumor

硬膜内肿瘤
  • 文章类型: Journal Article
    此视频的目的是通过高质量的手术视频演示硬膜内脊膜瘤(ISM)切除术的技术细微差别。作者描述了3例颈髓质ISM患者,子宫颈,和胸部区域。患者在俯卧位行椎板切除术,背侧硬骨切开术,然后切除肿块.病例1需要枕下开颅术和肿瘤远离椎动脉的解剖。在情况2中,特别强调用绳索旋转切开齿状韧带。案例3突出了细致的环状蛛网膜释放和超声的使用。患者术后神经功能明显改善。此视频提供了有关ISM移除的特定位置技术细微差别的清晰说明。
    The objective of this video was to demonstrate technical nuances of intradural spinal meningioma (ISM) resection through a high-quality surgical video. The authors describe 3 patients with ISM in the cervicomedullary, cervical, and thoracic regions. Patients underwent surgery in the prone position with laminectomy, dorsal durotomy, and then resection of the mass. Case 1 required a suboccipital craniectomy and dissection of the tumor away from the vertebral artery. In case 2, special emphasis is placed on sectioning the dentate ligament with cord rotation. Case 3 highlights meticulous circumferential arachnoid release and the use of ultrasound. Patients saw significant neurological improvement postoperatively. This video provides clear instruction on location-specific technical nuances of ISM removal.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    一名患有肾细胞癌(RCC)的60岁男性出现背痛,弱点,肠和膀胱急迫。MRI显示L2处有马尾肿瘤。L1-3层切除术后,术中超声定位肿瘤。硬脑膜开放后,血管肿瘤粘附在马尾。术中神经刺激有助于识别神经小根。以零碎的方式去除肿瘤。肿瘤解剖导致L1-3分布的周期性痉挛。神经监测检查表用于恢复平均动脉压升高的运动诱发电位信号。血管肿瘤的止血具有挑战性。术中超声证实肿瘤缩小。病理证实为转移性肾癌。
    A 60-year-old male with renal cell carcinoma (RCC) presented with back pain, weakness, and bowel and bladder urgency. MRI demonstrated a cauda equina tumor at L2. Following L1-3 laminectomies, intraoperative ultrasound localized the tumor. After dural opening, a vascular tumor was adherent to the cauda equina. Intraoperative nerve stimulation helped to identify the nerve rootlets. Tumor was removed in a piecemeal fashion. Tumor dissection caused periodic spasms in L1-3 distributions. A neuromonitoring checklist was used to recover motor evoked potential signals with elevated mean arterial pressures. Hemostasis was challenging with the vascular tumor. Intraoperative ultrasound confirmed tumor debulking. Pathology confirmed metastatic RCC.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    目的:脊髓神经鞘瘤(SS)和脊髓脑膜瘤(SM)占大多数硬膜内髓外(IDEM)肿瘤。这些肿瘤通常是良性病变,通常对手术切除反应良好。到目前为止,很少有研究试图确定IDEM肿瘤的微创手术(MIS)和多模式术中神经生理监测(IONM)后的长期结果。这项研究的目的是介绍最大的病例系列之一,特别是使用管状牵开器系统进行MIS锁孔手术后的IONM发现和长期结果。
    方法:回顾性分析了2013年1月至2018年8月在多模式IONM下,经MIS-锁孔入路行肿瘤切除手术的87例IDEM肿瘤患者。术前和术后使用改良的McCormick分级量表评估神经状态。多模态IONM由运动诱发电位(MEP)组成,体感诱发电位(SEP),和肌电图(EMG)。回顾性分析了短期和长期临床评估以及患者的医疗档案。
    结果:手术切除SS49例,SM38例。肿瘤部位为宫颈16.1%,胸廓占48.3%,胸腰椎占4.6%,腰椎31%。在有2个SEP的9个手术(10.3%)中检测到严重的IONM变化,5个欧洲议会议员,和2个EMG事件。三个IONM更改(2个MEP,1EMG)被证明是自然界中的瞬时变化,因为它们在立即采取纠正措施的短时间内得到解决。6例永久性IONM改变的患者(2SEPs,3MEPs,1EMG事件),所有缺陷均在住院期间或短期随访评估中得到解决.灵敏度,特异性,IONM的正预测值和负预测值分别为100%、96%、67%和100%,分别。总切除率为100%,所有患者均表现出稳定或改善的麦考密克等级。在长期随访评估中(平均术后5.2±2.9年),未发现肿瘤复发和脊柱不稳定。总的来说,94%的患者对他们的手术满意或非常满意,根据Odom的标准,93%的患者报告了优异或良好的一般临床结果。
    结论:MIS-锁孔手术联合多模式IONM治疗IDEM肿瘤可获得较高的满意度和令人满意的长期临床和手术结果。
    OBJECTIVE: Spinal schwannomas (SS) and spinal meningiomas (SM) account for most intradural extramedullary (IDEM) tumors. These tumors are usually benign lesions, which generally respond favorably to surgical excision. Few studies up to now tried to determine the long-term outcome after minimally invasive surgery (MIS) with multimodal intraoperative neurophysiological monitoring (IONM) for IDEM tumors. The aim of this study was to present one of the largest case series with special regard to IONM findings and long-term outcome after MIS-keyhole surgery with a tubular retractor system.
    METHODS: Between January 2013 and August 2018, 87 patients with IDEM tumors who underwent tumor removal surgery via MIS-keyhole approach under multimodal IONM were retrospectively reviewed. The neurological status was assessed using a modified McCormick grading scale pre- and postoperatively. Multimodal IONM consisted of motor evoked potentials (MEP), somatosensory evoked potentials (SEP), and electromyography (EMG). Both short-term and long-term clinical evaluations as well as patients\' medical files were retrospectively analyzed.
    RESULTS: Surgeries were performed for resection of SS in 49 patients and SM in 38 patients. Tumor locations were cervical in 16.1%, thoracic in 48.3%, thoracolumbar in 4.6%, lumbar 31%. Critical IONM changes were detected in 9 operations (10.3%) in which there were 2 SEPs, 5 MEPs, and 2 EMG events. Three IONM changes (2 MEPs, 1 EMG) were turned out to be transient change in nature since they were resolved in a short time when immediate corrective actions were initiated. Six patients with permanent IONM changes (2SEPs, 3MEPs, 1EMG event), all deficits had resolved during hospitalization or on short -term follow-up evaluation. Sensitivity, specificity, and positive and negative predicted values of IONM were 100, 96, 67, and 100%, respectively. Gross total resection rate was 100%, and a stable or improved McCormick grade exhibited in all patients. No tumor recurrence and no spinal instability were found in the long-term follow-up evaluation (mean 5.2 ± 2.9 years postoperatively). Overall, 94% of patients were either satisfied or very satisfied with their operation, and 93% patients reported excellent or good general clinical outcome according to Odom\'s criteria.
    CONCLUSIONS: MIS-keyhole surgery with multimodal IONM for IDEM tumors enables a high level of satisfaction and a satisfying long-term clinical and surgical outcome.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    背景:原发性脊柱黑色素瘤极为罕见,占所有原发性黑色素瘤的1%。通常阴险地出现在胸脊髓中,原发性脊髓黑素瘤可因出血倾向而急性表现.
    方法:尽管它很少,当在磁共振成像中看到T1和T2强度的出血模式时,应将原发性脊柱黑色素瘤包括在鉴别诊断中。此外,完整的诊断至关重要,因为原发性脊柱黑色素瘤的预后比具有转移性扩散的原发性皮肤黑色素瘤的预后更有利。
    结论:切除是首选治疗方法,一些作者主张术后化疗,免疫疗法,和/或辐射。我们描述了一例出血性原发性脊柱黑色素瘤引起的急性四肢瘫痪,需要切除。
    BACKGROUND: Primary spinal melanoma is extremely rare, accounting for ∼1% of all primary melanomas. Typically presenting insidiously in the thoracic spinal cord, primary spinal melanomas can have an acute presentation due to their propensity to hemorrhage.
    METHODS: Despite its rarity, primary spinal melanoma should be included in the differential diagnosis when a hemorrhagic pattern of T1 and T2 intensities is seen on magnetic resonance imaging. Furthermore, the complete diagnosis is crucial because the prognosis of a primary spinal melanoma is considerably more favorable than that of a primary cutaneous melanoma with metastatic spread.
    CONCLUSIONS: Resection is the treatment of choice, with some authors advocating for postoperative chemotherapy, immunotherapy, and/or radiation. We describe a case of acute quadriplegia from hemorrhagic primary spinal melanoma requiring resection.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    在这个案例报告中,我们提出了一个独特的原因,在患有多发性终丝副神经节瘤的患者中,由于硬膜内腰椎肿瘤引起的尾骨痛。我们强调症状学,临床过程,和放射学发现。我们对文献的回顾证明,我们的病例是英语文献中首次报道的硬膜内马尾肿瘤伴尾骨痛。根据结果和对治疗的临床反应,我们对他的尾骨痛的可能解剖机制提出了大胆的假设。
    In this case report, we present a unique cause of coccygodynia due to an intradural lumbar spinal tumour in a patient with multiple filum terminale paragangliomas. We highlight the symptomatology, the clinical course, and the radiological findings. Our review of the literature proved our case to be the first report of an intradural cauda equina tumour presenting with coccygodynia in English literature. Based on the outcome and clinical response to treatment we make a bold hypothesis on the possible anatomical mechanism of his coccygodynia.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    神经性疼痛表现出负担和损害性状况,有时可能在脊柱肿瘤手术后发生。虽然它已经在周围神经鞘瘤中被描述,其他硬膜内肿瘤患者的数据很少。我们在此介绍了接受不同硬膜内脊柱肿瘤手术的大型队列人群,评估术后早期和随访结果。关注神经性疼痛的发生。我们进行了一项回顾性单中心研究,包括2009年至2020年期间所有接受硬膜内脊柱肿瘤治疗的患者。我们从记录中提取了手术方面以及术前和术后临床过程。进行了潜在影响预后因素的统计分析,包括配对分析。总的来说,360名患者被纳入分析。在平均随访2年时,26/360例患者抱怨神经性疼痛综合征(7.2%)需要持续用药。在这些患者中,只有50%的患者在术前抱怨疼痛。肿瘤实体没有显着影响术后神经性疼痛的发生率(p=0.91)。带有神经根的肿瘤的牺牲和肿瘤复发也没有增加这种情况的风险。在我们的队列中,需要持续治疗的持续性神经性疼痛发生在接受硬膜内脊柱手术的患者中有7.2%。这种经常被低估的术后不良事件代表一种致残状况,导致受影响患者的生活质量严重受损。
    Neuropathic pain presents a burdening and impairing condition which may occasionally occur after spinal tumor surgery. While it has been described in peripheral nerve sheath tumors, data on other intradural tumor patients is sparse. We hereby present a large cohort population undergoing different intradural spinal tumor surgery with assessment of early postoperative and follow-up outcomes, focusing on the occurrence of neuropathic pain. We performed a retrospective monocentric study including all patients treated for intradural spinal tumors between 2009 and 2020. We extracted surgical aspects as well as pre- and postoperative clinical courses from the records. Statistical analysis of potential contributing prognostic factors was performed including matched pair analysis. In total, 360 patients were included for analysis. At a median follow-up of 2 years, 26/360 patients complained of a neuropathic pain syndrome (7.2%) requiring continuous medication. Of these patients only 50% complained preoperatively of pain. Tumor entity did not significantly influence the incidence of postoperative neuropathic pain (p = 0.91). Sacrifice of the tumor carrying nerve root and tumor recurrence also did not increase the risk for this condition. Persistent neuropathic pain requiring continuous treatment occurred in 7.2% of patients undergoing intradural spinal surgery in our cohort. This frequently underestimated postoperative adverse event represents a disabling condition leading to a substantial impairment in the quality of life among the affected patients.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    马尾神经鞘瘤是罕见的硬膜内原发性脊柱肿瘤。这些患者中许多最初出现马尾神经综合征,只有2.2%的患者出现临床复发。总切除是选择的程序。
    一名62岁女性5年前接受了马尾神经鞘瘤切除术。她新近出现了归因于复发性神经鞘瘤的马尾神经症状。在完全切除继发性肿瘤后,患者的术前缺陷完全解决,肿瘤从未复发.
    马尾神经鞘瘤的二次全切除对于避免肿瘤进一步复发至关重要。
    UNASSIGNED: Schwannomas of the cauda equina are rare intradural primary spinal tumors. Many of these patients initially present with cauda equina syndromes, and only 2.2% demonstrate clinical recurrence. Gross total excision is the procedure of choice.
    UNASSIGNED: A 62-year-old female had undergone resection of a cauda equina schwannoma 5 years previously. She newly presented with cauda equina symptoms attributed to a recurrent schwannoma. Following gross total secondary tumor resection, the patient\'s preoperative deficits fully resolved, and the tumor never recurred.
    UNASSIGNED: Secondary gross total excision of schwannomas of the cauda equina is critical to avoid further tumor recurrence.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    儿童广泛的多灶性硬膜内病变提出了巨大的挑战。此手术视频说明了我们对一个14岁的男孩的管理,该男孩在磁共振成像(MRI)上有两个硬膜内肿块:一个在T2-5,另一个从T12通过the囊。在一个单一的过程中,我们进行了T2-5椎板切除术和椎板成形术以及T12骶骨椎板切除术用于肿瘤切除术.为了重建,我们通过T11-L2后路脊柱固定和同种异体植骨融合在胸腰椎交界处进行了完整的椎板成形术。在这个视频中,我们说明了胸髓和马尾神经硬膜内肿瘤切除的显微外科挑战。在年轻患者中,术后脊柱畸形的预防是最重要的问题。我们讨论了青少年中长节段脊柱稳定的考虑因素,并描述了我们在胸腰椎交界处进行稳定以补充椎板成形术同时保留功能的决策。病人和他们的家人同意手术。0:51的文章图像来自McGirt等人,椎板成形术与椎板切除术切除硬膜内脊柱肿瘤后的短期进行性脊柱畸形:239例患者的分析,神经外科,2010,66(5),1005-1012,经神经外科医师大会许可。
    Extensive multifocal intradural lesions in children present a formidable challenge. This surgical video illustrates our management of a 14-yr=old boy with two intradural mass lesions on magnetic resonance imaging (MRI): one at T2-5 and the other from T12 through the sacral cul-de-sac. In a single procedure, we performed a T2-5 laminectomy and laminoplasty and T12-sacrum laminectomy for tumor resection. For reconstruction, we performed complete laminoplasty at all levels with supplementation at the thoracolumbar junction via T11-L2 posterior spinal fixation and allograft placement for fusion. In this video, we illustrate the microsurgical challenges of intradural tumor resection in both the thoracic cord and amidst the cauda equina. In young patients, prevention of postsurgical spinal deformity is of paramount concern. We discuss considerations for long-segment spinal stabilization in an adolescent and describe our decision-making to perform stabilization at the thoracolumbar junction to supplement laminoplasty while preserving function. The patient and their family consented to the procedure.  Image of the article at 0:51 is from McGirt et al, Short-term progressive spinal deformity following laminoplasty versus laminectomy for resection of intradural spinal tumors: analysis of 239 patients, Neurosurgery, 2010, 66(5), 1005-1012, by permission of the Congress of Neurological Surgeons.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    腰骶部Tarlov囊肿(TC)很少见破裂。这里,我们报告了一个不寻常的表现,即TC破裂伴椎管内出血,模仿癌病。通过经皮穿刺活检获得病理诊断。采用了保守的方法,取得了出色的结果。因此,在这种情况下,破裂的出血性TC应进行鉴别诊断,以推动适当的临床治疗决策.
    Lumbosacral Tarlov cysts (TCs) have rarely been seen to rupture. Here, we report an unusual presentation of a ruptured TC with intraspinal hemorrhage mimicking carcinomatosis. Pathological diagnosis was obtained using percutaneous biopsy. A conservative approach was utilized and an excellent outcome was achieved. Thus, in cases such as this, a ruptured hemorrhagic TC should be on the differential diagnosis to drive appropriate clinical management decisions.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号