PDF(Pubmed)
Abstract：
BACKGROUND: Primary spinal melanoma is extremely rare, accounting for ∼1% of all primary melanomas. Typically presenting insidiously in the thoracic spinal cord, primary spinal melanomas can have an acute presentation due to their propensity to hemorrhage.
METHODS: Despite its rarity, primary spinal melanoma should be included in the differential diagnosis when a hemorrhagic pattern of T1 and T2 intensities is seen on magnetic resonance imaging. Furthermore, the complete diagnosis is crucial because the prognosis of a primary spinal melanoma is considerably more favorable than that of a primary cutaneous melanoma with metastatic spread.
CONCLUSIONS: Resection is the treatment of choice, with some authors advocating for postoperative chemotherapy, immunotherapy, and/or radiation. We describe a case of acute quadriplegia from hemorrhagic primary spinal melanoma requiring resection.
METHODS: Despite its rarity, primary spinal melanoma should be included in the differential diagnosis when a hemorrhagic pattern of T1 and T2 intensities is seen on magnetic resonance imaging. Furthermore, the complete diagnosis is crucial because the prognosis of a primary spinal melanoma is considerably more favorable than that of a primary cutaneous melanoma with metastatic spread.
CONCLUSIONS: Resection is the treatment of choice, with some authors advocating for postoperative chemotherapy, immunotherapy, and/or radiation. We describe a case of acute quadriplegia from hemorrhagic primary spinal melanoma requiring resection.
摘要：
背景：原发性脊柱黑色素瘤极为罕见，占所有原发性黑色素瘤的1%。通常阴险地出现在胸脊髓中，原发性脊髓黑素瘤可因出血倾向而急性表现.
方法：尽管它很少，当在磁共振成像中看到T1和T2强度的出血模式时，应将原发性脊柱黑色素瘤包括在鉴别诊断中。此外，完整的诊断至关重要，因为原发性脊柱黑色素瘤的预后比具有转移性扩散的原发性皮肤黑色素瘤的预后更有利。
结论：切除是首选治疗方法，一些作者主张术后化疗，免疫疗法，和/或辐射。我们描述了一例出血性原发性脊柱黑色素瘤引起的急性四肢瘫痪，需要切除。
方法：尽管它很少，当在磁共振成像中看到T1和T2强度的出血模式时，应将原发性脊柱黑色素瘤包括在鉴别诊断中。此外，完整的诊断至关重要，因为原发性脊柱黑色素瘤的预后比具有转移性扩散的原发性皮肤黑色素瘤的预后更有利。
结论：切除是首选治疗方法，一些作者主张术后化疗，免疫疗法，和/或辐射。我们描述了一例出血性原发性脊柱黑色素瘤引起的急性四肢瘫痪，需要切除。
