incisional hernia

切口疝
  • 文章类型: Journal Article
    我们的研究解决了腹侧疝修补术文献中的空白,关于机器人经腹直肌后脐假体修复(r-TARUP)治疗原发性和切口腹侧疝的长期有效性。本研究旨在报告3年复发率和总体患者预后,包括生活质量。
    对2018年8月至2022年1月的101例择期r-TARUP患者进行前瞻性收集数据的回顾性分析。收集的数据包括人口统计,疝气大小,网格类型,术后结局和手术前后的欧洲疝学会生活质量问卷(EuraHS-QoL)。
    该组患者的平均年龄为53岁,平均体重指数(BMI)为32kg/m,54%的切口疝和46%的原发性疝,平均长度和宽度分别为4.4厘米和6.1厘米,利用合成的58%和生物可吸收的42%网眼类型。大多数被归类为疾病控制和预防中心(CDC)一级伤口。术后并发症包括血清肿(2%),血肿(3%),这需要手术干预,与网格类型没有显著相关性。腹横肌释放(TAR)与住院时间增加之间存在强正相关(相关系数:0.731,p<0.001)。与术后3年的评估相比,术前生活质量评估显示出统计学上的显着改善。平均值(±SD)为61.61±5.29与13.84±2.6(p<0.001)。平均随访34.4个月,1年无疝气复发,2-3年随访3次复发(3.2%)。
    r-TARUP技术已被证明对修复原发性和切口腹侧疝是安全有效的,随访期间复发率低,生活质量(QoL)明显改善。
    UNASSIGNED: Our study addresses the gap in ventral hernia repair literature, regarding the long-term effectiveness of robotic transabdominal retrorectus umbilical prosthetic repair (r-TARUP) for primary and incisional ventral hernias. This study aimed to report the 3-year recurrence rates and overall patient outcomes including quality of life.
    UNASSIGNED: A retrospective review of prospective collected data analyzed 101 elective r-TARUP patients from August 2018 to January 2022. Data collected included demographics, hernia sizes, mesh types, postoperative outcomes and the European Hernia Society Quality of Life questionnaire (EuraHS-QoL) before and after surgery.
    UNASSIGNED: The average age of the group of patients was 53, having a mean body mass index (BMI) of 32 kg/m, with 54% incisional and 46% primary hernias, with mean length and width of 4.4 cm and 6.1 cm, utilizing synthetic 58% and bioabsorbable 42% mesh types. The majority were classified as Centers of Disease Control and Prevention (CDC) class I wounds. Postoperative complications included seroma (2%), hematoma (3%), which required surgical intervention, with no significant correlation to mesh type. A strong positive correlation was found between Transversus Abdominis Release (TAR) and increased length of hospital stay (correlation coefficient: 0.731, p < 0.001). Preoperative quality of life assessments demonstrated statistically significant improvements when compared to postoperative assessments at 3 years, with a mean (±SD) of 61.61 ± 5.29 vs. 13.84 ± 2.6 (p < 0.001). Mean follow up of 34.4 months with no hernia recurrence at 1 year and 3 recurrence at the 2-3 years follow up (3.2%).
    UNASSIGNED: The r-TARUP technique has proven to be safe and effective for repairing primary and incisional ventral hernias, with a low recurrence rate during this follow up period with a noticeable improvement in quality of life (QoL).
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  • 文章类型: Journal Article
    背景:会阴疝(PH)是腹部手术切除(APR)的晚期并发症,可能会损害患者的生活质量。机器人APR采用近期直肠癌治疗策略后PH的频率和危险因素仍不清楚。
    方法:对2011年12月至2022年6月接受机器人APR治疗的直肠癌患者进行回顾性检查。从2020年7月开始,骨盆加固程序,例如骨盆腹膜和肛提肌的机器人闭合,在可行的情况下作为PH的预防程序进行。手术后1年使用计算机断层扫描诊断有或无症状的患者的PH。我们检查了PH的频率,有PH(PH+)和无PH(PH-)患者之间的比较特征,并确定了PH的危险因素。
    结果:我们评估了142例患者,其中PH+53(37.3%),PH-89(62.6%)。PH+的术前放化疗率明显较高(26.4%对10.1%,p=0.017),并且接受骨盆加固手术的比率显着降低(1.9%对14.0%,p=0.017)。PH+侧方淋巴结清扫率较低(47.2%对61.8%,p=0.115)和更短的手术时间(340分钟对394分钟,p=0.110)。根据多变量分析,PH的独立危险因素为术前放化疗,没有进行外侧淋巴结清扫术,也没有接受骨盆加固手术.
    结论:在最近的直肠癌治疗策略下,机器人APR治疗直肠癌后的PH并不是罕见的并发症,应考虑对PH进行预防性操作。
    BACKGROUND: Perineal hernia (PH) is a late complication of abdominoperineal resection (APR) that may compromise a patient\'s quality of life. The frequency and risk factors for PH after robotic APR adopting recent rectal cancer treatment strategies remain unclear.
    METHODS: Patients who underwent robotic APR for rectal cancer between December 2011 and June 2022 were retrospectively examined. From July 2020, pelvic reinforcement procedures, such as robotic closure of the pelvic peritoneum and levator ani muscles, were performed as prophylactic procedures for PH whenever feasible. PH was diagnosed in patients with or without symptoms using computed tomography 1 year after surgery. We examined the frequency of PH, compared characteristics between patients with PH (PH+) and without PH (PH-), and identified risk factors for PH.
    RESULTS: We evaluated 142 patients, including 53 PH+ (37.3%) and 89 PH- (62.6%). PH+ had a significantly higher rate of preoperative chemoradiotherapy (26.4% versus 10.1%, p = 0.017) and a significantly lower rate of undergoing pelvic reinforcement procedures (1.9% versus 14.0%, p = 0.017). PH+ had a lower rate of lateral lymph node dissection (47.2% versus 61.8%, p = 0.115) and a shorter operative time (340 min versus 394 min, p = 0.110). According to multivariate analysis, the independent risk factors for PH were preoperative chemoradiotherapy, not undergoing lateral lymph node dissection, and not undergoing a pelvic reinforcement procedure.
    CONCLUSIONS: PH after robotic APR for rectal cancer is not a rare complication under the recent treatment strategies for rectal cancer, and performing prophylactic procedures for PH should be considered.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    目的:我们旨在评估切口疝修补术后术后前30天的手术伤口并发症对患者长期生活质量的影响。此外,还将评估手术技术和术前合并症对患者生活质量的影响.
    方法:前瞻性队列研究,该研究使用onlay和后肌技术评估了2019年至2020年间接受切口疝修补术的115例患者。这些患者最初在术后前30天评估手术伤口结果(手术部位感染(SSI)或手术部位发生(SSO))。然后,三年后评估,通过一份特定的生活质量问卷,疝相关生活质量调查(HerQLes)。
    结果:一些患者在研究期间失去随访,由于死亡,接触困难,拒绝回答问卷,对80例患者进行了评估。其中,11例患者(13.8%)在术后前30天有SSI,37例(46.3%)有某种类型的SSO。未发现SSI和SSO对生活质量指数的影响。在分析其他变量时,我们观察到体重指数(BMI)对患者的生活质量有显著影响.同样,疝大小和网孔大小被确定为与较差生活质量结局相关的变量.在使用的手术技术方面没有观察到差异。
    结论:在本研究中,使用HerQLes评分未发现手术伤口结局(SSO和SSI)与较差的生活质量结果之间的关系.我们观察到BMI以及网眼和疝气的大小与生活质量指数呈成反比关系。然而,应开展更多的研究评估术前生活质量指数,并将其与术后指标进行比较,以评估这些相关性。
    OBJECTIVE: We aim to evaluate the impact of surgical wound complications in the first 30 postoperative days after incisional hernia repair on the long-term quality of life of patients. In addition, the impact of the surgical technique and preoperative comorbidities on the quality of life of patients will also be evaluated.
    METHODS: Prospective cohort study, which evaluates 115 patients who underwent incisional hernioplasty between 2019 and 2020, using the onlay and retromuscular techniques. These patients were initially assessed with regard to surgical wound outcomes in the first 30 postoperative days (surgical site infection (SSI) or surgical site occurrence (SSO)), and then, assessed after three years, through a specific quality of life questionnaire, the Hernia Related Quality of Life Survey (HerQLes).
    RESULTS: After some patients were lost to follow-up during the study period, due to death, difficulty in contact, refusal to respond to the questionnaire, eighty patients were evaluated. Of these, 11 patients (13.8%) had SSI in the first 30 postoperative days and 37 (46.3%) had some type of SSO. The impact of both SSI and SSO on quality of life indices was not identified. When analyzing others variables, we observed that the Body Mass Index (BMI) had a significant impact on the patients\' quality of life. Likewise, hernia size and mesh size were identified as variables related to a worse quality of life outcome. No difference was observed regarding the surgical techniques used.
    CONCLUSIONS: In the present study, no relationship was identified between surgical wound outcomes (SSO and SSI) and worse quality of life results using the HerQLes score. We observed that both BMI and the size of meshes and hernias showed an inversely proportional relationship with quality of life indices. However, more studies evaluating preoperative quality of life indices and comparing them with postoperative indices should be carried out to evaluate these correlations.
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  • 文章类型: Journal Article
    饮食因素与疝气之间的关系目前尚不清楚。
    英国生物库用于提取用作暴露的饮食因素,包括酒精的摄入,非油性鱼,牛肉,新鲜水果,油性鱼,沙拉/生蔬菜,干果,咖啡,麦片,盐,茶,水,煮熟的蔬菜,奶酪,羊肉/羊肉,猪肉,家禽,加工肉,和面包。FinnGen生物库用于获得关于疝气的GWAS数据作为结果。这项研究的主要分析是使用加权中位数进行的,MR-Egger,和IVW方法。Cochran的Q检验用于评估异质性。为了找到潜在的异常值,使用MR-PRESSO方法。采用留一法分析评估IVW方法的稳健性。
    每周饮酒(OR:0.614;p=0.00614)可降低腹股沟疝的风险。饮酒频率(OR:1.309;p=0.0477)增加了腹侧疝(主要包括切口疝和造口旁疝)的风险。摄入非油性鱼(OR:2.945;p=0.0214)会增加腹股沟疝的风险。添加到食物中的盐(OR:1.841;p=0.00267)会增加脐疝的风险。奶酪摄入量(OR:0.434;p=0.000536)和干果摄入量(OR:0.322;p=0.00716)降低了腹壁疝的风险,而摄入煮熟的蔬菜(OR:4.475;p=0.0380)会增加腹侧疝的风险。未发现其他饮食因素与疝气的因果关系。
    腹股沟,脐带缆,脐带缆腹侧疝都与饮食因素有关。
    UNASSIGNED: The relationship between dietary factors and hernias is currently unclear.
    UNASSIGNED: The UK Biobank was used to extract dietary factors that were used as exposures, including intake of alcohol, non-oily fish, beef, fresh fruit, oily fish, salad/raw vegetables, dried fruit, coffee, cereal, salt, tea, water, cooked vegetables, cheese, Lamb/mutton, pork, poultry, processed meat, and bread. The FinnGen biobank was used to obtain GWAS data on hernias as outcomes. The main analysis of this study was performed using the weighted median, MR-Egger, and IVW methods. Cochran\'s Q test was utilized to assess heterogeneity. To find potential outliers, the MR-PRESSO method was used. Leave-one-out analysis was employed to assess the IVW method\'s robustness.
    UNASSIGNED: Alcoholic consumption per week (OR: 0.614; p = 0.00614) reduced the risk of inguinal hernia. Alcohol intake frequency (OR: 1.309; p = 0.0477) increased the risk of ventral hernia (mainly including incisional hernia and parastomal hernia). The intake of non-oily fish (OR: 2.945; p = 0.0214) increased the risk of inguinal hernia. Salt added to food (OR: 1.841; p = 0.00267) increased the risk of umbilical hernia. Cheese intake (OR: 0.434; p = 0.000536) and dried fruit intake (OR: 0.322; p = 0.00716) decreased the risk of ventral hernia, while cooked vegetable intake (OR: 4.475; p = 0.0380) increased the risk of ventral hernia. No causal relationships were found with hernias from other dietary factors.
    UNASSIGNED: Inguinal, umbilical, and ventral hernias are all related to dietary factors.
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  • 文章类型: Case Reports
    用不可吸收的网状物修复腹壁切口疝是普外科中最常见的手术之一。网状物迁移到肠道是罕见的,但严重的并发症。它可以在手术后数月甚至数年发生,并且经常表现为模糊的腹痛,让诊断变得棘手.
    方法:我们报告了一例罕见的病例,一例52岁的女性出现小肠梗阻,继发于网状物从腹壁迁移到肠道,腹侧切口疝反复手术修复10年后。在手术中,一个网眼被迁移到一个小碗里。患者进行了小肠切除术。术后病程简单,5天后出院。
    方法:带网片的切口疝修补术是全世界最常用的外科手术之一。许多并发症与网状物的使用有关;其中最常见的是血清肿,血肿,和感染。网状物迁移在切口疝修补术后仍然是一个罕见的事件,当考虑在肠腔内完全迁移时,甚至更罕见。这种并发症的确切原因仍然未知。对于网格迁移已经提出了多种假设。腹痛,间歇性或持续性肠梗阻,质量形成,内脏穿孔是最常见的临床表现。建议通过腹腔镜或剖腹手术完全去除网孔,以及器官的部分或全部切除。
    结论:在切口疝网片修补术的情况下,网片迁移是一种罕见的并发症,通常需要手术干预。
    UNASSIGNED: Repairing incisional abdominal wall hernia with nonabsorbable meshes is one of the most common procedures in general surgery. Mesh migration into the intestine is rare but a serious complication. It can occur months or even years after surgery and often presents with vague abdominal pain, making diagnosis tricky.
    METHODS: We report a rare case of a 52-year-old female presenting a small bowel obstruction secondary to mesh migration from the abdominal wall into the intestine, 10 years after repeated surgical repair of a ventral incisional hernia. At surgery, a mesh was migrated into a small bowl. The patient had a small bowel resection. The postoperative course was simple and the patient was discharged after 5 days.
    METHODS: Incisional hernia repair with mesh is one of the most commonly performed surgical procedures worldwide. Many complications have been linked to the use of mesh; among the most frequently reported are seromas, hematomas, and infections. Mesh migration remains an uncommon event after incisional hernia repair, and even rarer when considering complete migration within the intestinal lumen. The exact cause of this complication remains unknown. Multiple hypotheses have been proposed for mesh migration. Abdominal pain, intermittent or persistent intestinal obstruction, mass formation, and viscus perforation represent the most common clinical manifestation. Total removal of the mesh via laparoscopy or laparotomy is recommended, along with either partial or entire resection of the organ.
    CONCLUSIONS: Mesh migration is a an uncommon possible complication in case of incisional hernia mesh repair and it requires often surgical intervention.
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  • 文章类型: Journal Article
    背景:通过分离腹壁,腹横肌释放(TAR)允许重建腹壁并放置大网孔,以治疗许多类型的疝。然而,在临界情况下,层的流动性不足,和额外的桥接技术可能需要无张力闭合。我们现在提供这方面的数据。患者和方法:2023年,作为疝修补术的一部分,我们对50例患者进行了腹横肌松解术。该程序是使用开放式(n=25)进行的,机器人(n=24),和腹腔镜(n=1)技术。疝囊总是整合到前缝线中,在内侧疝的情况下,用于lineaalba重建。结果:对于内侧疝,22例进行了开放性TAR。在这些病例中,有7例进行了额外的后路桥接。在没有桥接的患者中,TAR平面中的网孔尺寸与缺损面积(中位数,厘米)的比率为1200cm2/177cm2=6.8,和1750cm2/452cm2=3.8的那些桥接。手术时间(以分钟为中位数)为139和222分钟,住院时间为6和10天,分别。机器人TAR主要用于外侧和造口旁疝。这些手术的中位数为143和242分钟,住院时间是2天和3天,分别。对于机器人修复,3例进行后路桥接。讨论:使用TAR技术,即使是复杂的疝气也可以安全修复。额外的后部桥接提供了后部平面与肠的可靠分离。因此,疝囊始终可用于白线的前部重建。该技术可以实施为开放式或微创手术。
    Background: By separating the abdominal wall, transversus abdominis release (TAR) permits reconstruction of the abdominal wall and the placement of large mesh for many types of hernias. However, in borderline cases, the mobility of the layers is inadequate, and additional bridging techniques may be required for tension-free closure. We now present our own data in this regard. Patients and Methods: In 2023, we performed transversus abdominis release on 50 patients as part of hernia repair. The procedures were carried out using open (n = 25), robotic (n = 24), and laparoscopic (n = 1) techniques. The hernia sac was always integrated into the anterior suture and, in the case of medial hernias, was used for linea alba reconstruction. Results: For medial hernias, open TAR was performed in 22 cases. Additional posterior bridging was performed in 7 of these cases. The ratio of mesh size in the TAR plane to the defect area (median in cm) was 1200cm2/177 cm2 = 6.8 in patients without bridging, and 1750cm2/452 cm2 = 3.8 in those with bridging. The duration of surgery (median in min) was 139 and 222 min and the hospital stay was 6 and 10 days, respectively. Robotic TAR was performed predominantly for lateral and parastomal hernias. These procedures took a median of 143 and 242 min, and the hospital stay was 2 and 3 days, respectively. For robotic repair, posterior bridging was performed in 3 cases. Discussion: Using the TAR technique, even complex hernias can be safely repaired. Additional posterior bridging provides a reliable separation of the posterior plane from the intestines. Therefore, the hernia sac is always available for anterior reconstruction of the linea alba. The technique can be implemented as an open or minimally invasive procedure.
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  • 文章类型: Case Reports
    背景技术切口腹侧疝代表腰椎外侧手术后的并发症。考虑到腰椎外侧椎间融合率的增加,腹侧疝的发生率会增加。由于没有使用术前肉毒杆菌注射进行开放性巨大腹侧疝修补术的报道,我们试图发表这项技术,为外科医生提供一种创新的方法,用于术前治疗巨大腹侧疝患者.病例报告一名有冠状动脉疾病史的75岁男子,慢性肾病,并提出了腹部疝修补术,以评估左外侧腹部和左下背部膨出5个月。症状在L2-L4腰椎外侧融合后开始。体格检查显示左后侧腹隆起。计算机断层扫描(CT)显示左后外侧腹部疝。患者计划在CT引导下进行腹壁外侧肉毒杆菌注射,然后是开放性腹侧疝修补术.他很好地忍受了手术,因为控制疼痛而入院,并在第二天出院。在3个月时进行CT重复成像,未发现患者先前的疝缺损。结论开放性腹侧疝修补术,术前注射肉毒杆菌毒素,允许最佳可视化和重新逼近侧腹疝缺损的肌筋膜成分。未能达到足够的肌筋膜和皮肤闭合,随着网格加固,在开放性腹侧疝修补术可导致各种手术部位并发症,包括切口侧腹疝复发。我们建议进一步研究肉毒杆菌注射作为治疗巨大腹侧疝的辅助手段的益处。
    BACKGROUND Incisional flank hernias represent a complication after lateral lumbar spine surgery. Given the increasing rate of lateral lumbar interbody fusions, the rate of incisional flank hernias will increase. Since there are no reports of open massive flank hernia repair utilizing preoperative botulinum injections, we sought to publish this technique to provide surgeons with an innovative method for preoperatively treating patients with massive flank hernias. CASE REPORT A 75-year-old man with a history of coronary artery disease, chronic kidney disease, and abdominal hernia repair presented for evaluation of left lateral abdominal and left lower back bulging for 5 months. The symptoms began after an L2-L4 lateral lumbar spinal fusion. Physical examination revealed a left posterior lateral flank bulge. Computed tomography (CT) showed a fat-containing left posterolateral abdominal hernia. The patient was scheduled for CT-guided lateral abdominal wall botulinum injections, followed by open flank hernia repair. He tolerated the surgery well, was admitted for pain control, and discharged on day 2. Repeat imaging with CT at 3 months showed no evidence of patient\'s prior hernia defect. CONCLUSIONS Open flank hernia repair, in conjunction with preoperative botulinum toxin injections, allows for optimal visualization and re-approximation of the myofascial components of flank hernia defects. Failure to achieve adequate myofascial and skin closure, along with mesh reinforcement, in open flank hernia repair can result in various surgical site complications, including incisional flank hernia recurrence. We recommend further investigation on the benefits of botulinum injections as an adjunct in management of massive flank hernias.
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  • 文章类型: Journal Article
    目的:切口疝(IH)是腹部中线闭合后的常见并发症,具有显著的相关发病率。随机对照试验表明,小叮咬技术(SBT)和预防性网状增强(PMA)可以减少IH相比,但是缺乏有关其在当代外科手术中实施的数据。这项调查旨在评估SBT和PMA的使用情况,并确定与采用SBT和PMA相关的因素。
    方法:在2023年1月22日至2023年3月16日之间,英国各地的顾问外科医生被要求完成一项25个问题的关于选择性初级中线切口闭合的调查。
    结果:在38个NHS信托基金中,675名合格外科医生中的267名(39.6%)收到了回复。受访者平均分为三级中心(47.6%)和地区综合医院(49.4%)。19.9%和3.0%的受访者使用了SBT和PMA,分别。与其他技术相比,使用SBT的外科医生更有可能仅闭合前腱膜层,使用单缝线,2-0号缝线和锋利的针尖,并常规解剖腹部以帮助闭合(所有p<0.001)。参加有关SBT的讲座/会议(p=0.043)和基于现有证据的实践(p<0.001)与SBT的使用独立相关。采用SBT最常见的障碍是缺乏证据(23.8%)和认为个人IH率低(16.8%)。
    结论:英国少数顾问外科医生采用了SBT或PMA。实践变革应由当前证据和程序信息的更广泛传播来驱动。
    OBJECTIVE: Incisional herniation (IH) is a frequent complication following midline abdominal closure with significant associated morbidity. Randomized controlled trials have demonstrated that the small bites technique (SBT) and prophylactic mesh augmentation (PMA) may reduce IH compared to mass closure techniques, but data are lacking on their implementation in contemporary surgical practice. This survey aimed to evaluate the use of the SBT and PMA and to identify factors associated with their adoption.
    METHODS: Between 22 January 2023 and 16 March 2023, consultant surgeons across the UK were asked to complete a 25-question survey on closure of an elective primary midline incision.
    RESULTS: Responses were received from 267 of 675 eligible surgeons (39.6%) in 38 NHS Trusts. Respondents were evenly split between tertiary centres (47.6%) and district general hospitals (49.4%). SBT and PMA were used by 19.9% and 3.0% of respondents, respectively. Compared to other techniques, surgeons using the SBT were more likely to close the anterior aponeurotic layer only, use single suture filaments, 2-0 gauge sutures and sharp needle points and routinely dissect abdominal layers to aid closure (all p < 0.001). Attendance at lectures/conferences on SBT (p = 0.043) and basing practice on available evidence (p < 0.001) were independently associated with use of the SBT. The commonest barriers to adopting SBT were a perceived lack of evidence (23.8%) and belief that personal IH rates were low (16.8%).
    CONCLUSIONS: A minority of UK consultant surgeons have adopted the SBT or PMA. Practice change should be driven by more widespread dissemination of current evidence and procedural information.
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  • 文章类型: Journal Article
    许多国家已经提出了活体肝移植(LDLT)以减少器官短缺。虽然早期的术后结果已经得到了很好的研究,对活体捐献者的长期随访知之甚少。我们,因此,设计了一项系统的文献综述,以探讨活体捐献者的长期并发症和生活质量.我们搜索了MEDLINE和EMBASE注册自2013年以来发表的研究,这些研究专门针对活体肝脏捐赠后的长期随访。涉及生理和心理方面。随访时间短于1年或未明确说明结果时机的出版物被排除在外。最初确定了总共2505篇论文。经过彻底的选择,17篇文章被确定为符合资格标准。所选文章主要来自北美和东方国家。随访期为1至11.5年。最常见的并发症是切口部位不适(13.2-38.8%)和精神疾病(1-22%)。胆道狭窄发生在1-14%的病例中。微创供肝切除术可改善患者生活质量,但长期数据有限。在首次报道LDLT大约30年后,关于活体捐献者的长期后续行动的报道很少。不同的因素可能会导致这种差距,包括事实,作为健康的个体,在中期随访期间,活体捐献者经常丢失。尽管报道的研究似乎证实了长期的供体安全性,需要进一步的研究来解决该手术的实际长期影响.
    Living donor liver transplantation (LDLT) has been proposed in many countries to reduce organ shortage. While the early postoperative outcomes have been well investigated, little is known about the long-term follow-up of the living donors. We, therefore, designed a systematic review of the literature to explore long-term complications and quality of life among living donors. We searched MEDLINE and EMBASE registries for studies published since 2013 that specifically addressed long-term follow-up following living-donor liver donation, concerning both physical and psychological aspects. Publications with a follow-up shorter than 1 year or that did not clearly state the timing of outcomes were excluded. A total of 2505 papers were initially identified. After a thorough selection, 17 articles were identified as meeting the eligibility criteria. The selected articles were mostly from North America and Eastern countries. Follow-up periods ranged from 1 to 11.5 years. The most common complications were incision site discomfort (13.2-38.8%) and psychiatric disorders (1-22%). Biliary strictures occurred in 1-14% of cases. Minimally invasive donor hepatectomy could improve quality of life, but long-term data are limited. About 30 years after the first reported LDLT, little has been published about the long-term follow-up of the living donors. Different factors may contribute to this gap, including the fact that, as healthy individuals, living donors are frequently lost during mid-term follow-up. Although the reported studies seem to confirm long-term donor safety, further research is needed to address the real-life long-term impact of this procedure.
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