iatrogenic

医源性
  • 文章类型: Journal Article
    婴儿配方奶粉是指使用到1岁,在这一点上,儿童过渡到非婴儿配方奶粉或牛奶,取决于他们剩余的饮食摄入量。非婴儿配方奶粉和牛奶适合于平均体重为1岁(9-9.5公斤)的儿童;然而,可以为体重不足的儿童提供大量的蛋白质和/或电解质,特别是如果他们仍然严重依赖配方喂养来摄取热量。在这个简短的交流中,我们介绍了几例患者,这些患者在1岁时的配方转换后,接受了过量的营养.我们还提供建议,供临床医生在面对体重过轻的婴儿时考虑。
    Infant formulas are meant to be used until 1 year of age, at which point children are transitioned to non-infant formulas or cow\'s milk, depending on their remaining dietary intake. Noninfant formulas and cow\'s milk are appropriate for children who have an average weight at that 1-year mark (9-9.5 kg); however, can contribute significant protein and/or electrolytes to children who are underweight for age, particularly if they still rely heavily on formula feeding for their caloric intake. In this short communication, we present several cases of patients who received excessive amounts of nutrients for age following the formula transition at the 1-year mark. We also provide recommendations for clinicians to consider when faced with underweight infants who are meant to be transitioning off infant formulas.
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  • 文章类型: Journal Article
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  • 文章类型: English Abstract
    医源性冠状动脉夹层很少见,但可能很严重。他们的管理很复杂,特别是如果在动脉腔中没有血管成形术引导的情况下进行解剖。在这种情况下,单靠血管造影是不够的,和冠状动脉内成像是必要的(使用光学相干或IVUS),以指导必要时的血管成形术(引导真腔,眼泪的覆盖范围)。我们在此报告在OFDI指导下治疗的右冠状动脉医源性解剖的情况。
    Iatrogenic coronary dissections are rare but potentially serious. Their management is complex, particularly if the dissection occurs without an angioplasty guide in the arterial lumen. In this context, angiography alone is insufficient, and endocoronary imaging is essential (using optical coherence or IVUS) to guide angioplasty when necessary (guide in the true lumen, coverage of the tear). We report here the case of an iatrogenic dissection of the right coronary artery treated with OFDI guiding.
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  • 文章类型: Journal Article
    噬血细胞性淋巴组织细胞增生症(HLH)可分为原发性(家族性,通常发生在婴儿中)或继发性(sHLH,发生在与各种疾病相关的任何年龄),主要是由感染引发的,自身免疫性疾病,和恶性状况。我们对sHLH病理生理学的理解仍在发展,以及与该综合征的原因和关联,由于这些实体的稀有性以及在报告这些实体的患者中经常出现的多种混杂因素,因此与医源性原因有关的那些被认为是最鲜为人知的。在这里,我们对文献进行了综述,以描述与医源性原因相关的sHLH的诊断和治疗挑战,并讨论了我们在更好地理解这些复杂情况以改善患者预后方面的一些挑战和未来方向.
    Hemophagocytic lymphohistiocytosis (HLH) can be categorized as either primary (familial, generally occurring in infants) or secondary (sHLH, occurring at any age in association with a variety of conditions) and is mainly triggered by infections, autoimmune diseases, and malignant conditions. Our understanding of the pathophysiology of sHLH is still evolving, and among the causes and associations with the syndrome, those putatively associated with iatrogenic causes remain among the most poorly understood due to the rarity of these entities and the multiple confounders so often present in the patients in whom they are reported. Herein, we present a review of the literature to describe the diagnostic and therapeutic challenges of sHLH associated with iatrogenic causes and discuss some of the challenges and future directions in our efforts to better understand these complex conditions for the advancement of patient outcomes.
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  • 文章类型: Case Reports
    在儿童腹股沟疝修补术中,医源性膀胱损伤是罕见的。对这些患者造成严重后果。由于这方面的信息匮乏,我们的目标是分享我们对这种罕见事件的治疗方法的经验。具体来说,一名22个月大的男性因呕吐入院,腹痛和无尿,腹股沟疝修补术后两天.该孩子腹股沟疝区域扩张,昏昏欲睡。诊断调查没有发现任何重大发现。在手术探查期间,我们发现膀胱损伤,而膀胱的大部分圆顶被结扎,随后坏死。在再次手术和持久的术后过程之后,病人终于康复了。目前,孩子正在观察中。因此,对于小儿外科医生来说,了解腹股沟疝修补术中膀胱损伤的可能性是至关重要的,管理这种并发症的方法,以及治疗过程中可能出现的各种问题。
    Iatrogenic injury of the bladder is a rare incidence during inguinal hernia repair in children, with serious consequences for such patients. Due to the scarcity of information on this matter, it is our goal to share our experience regarding the therapeutic approach to such a rare occurrence. Specifically, a 22-month-old male was admitted to our department with the complaint of vomiting, abdominal pain and anuria, two days after inguinal hernia repair. The child had distention of the inguinal hernia region and was lethargic. The diagnostic investigation did not reveal any significant findings. During surgical exploration, we discovered an injury to the bladder, while a large part of the dome of the bladder was ligated and subsequently became necrotic. After a reoperation and an enduring postoperative course, the patient finally recovered. Currently, the child is under observation. Therefore, it is of paramount importance for pediatric surgeons to be acquainted with the potential for bladder injury during inguinal hernia repair, ways to manage this complication, and various issues that may emerge during the therapeutic process.
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  • 文章类型: Journal Article
    研究在心脏外科手术过程中发生的医源性急性A型主动脉夹层(ATAD)的即时(表上)识别和手术治疗的短期和中期结果。
    从2016年1月至2020年12月在我们机构接受心脏外科手术的23,143名成年患者中,21名(0.09%)患有术中医源性ATAD并立即接受了主动脉修复。他们的临床特征,分析院内结局和随访结果.
    在21名患者中,13人(61.9%)患有高血压,14例(66.7%)升主动脉扩张。住院死亡率为9.5%,并记录了1例患者的永久性神经功能缺损新发.在36.0个月的中位随访中,所有18例随访患者均存活,没有重复手术.随访计算机断层扫描(CT)检查显示,3例患者的主动脉弓和8例的降主动脉中存在残留的假腔,其中1例存在残留的假腔灌注。
    在心脏外科手术中作为并发症发展的ATAD的立即识别和手术修复与低死亡率和高中期生存率相关。
    UNASSIGNED: To investigate short- and intermediate-term outcomes of immediate (on table) recognition and surgical treatment of iatrogenic acute type A aortic dissection (ATAD) that occurred during the course of the cardiac surgical procedures.
    UNASSIGNED: Of 23,143 adult patients undergoing cardiac surgical procedures at our institution from January 2016 to December 2020, 21 (0.09%) suffered from intraoperative iatrogenic ATAD and underwent immediate aortic repair. Their clinical characteristics, in-hospital outcomes and follow-up results were analyzed.
    UNASSIGNED: Among the 21 patients, 13 (61.9%) suffered from hypertension, and 14 (66.7%) had a dilated ascending aorta. In-hospital mortality was 9.5%, and new onset of permanent neurologic deficit was recorded in one patient. During a median follow-up of 36.0 months, all 18 follow-up patients survived without repeated surgeries. A follow-up computed tomography (CT) examination revealed a residual false lumen in the aortic arch in 3 patients and in the descending aorta in 8, with residual false lumen perfusion in one.
    UNASSIGNED: Immediate recognition and surgical repair of ATAD that developed as a complication during cardiac surgical procedures are associated with low mortality and high intermediate-term survival.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    本报告描述了一名虚弱的36岁患者的情况,该患者接受了右锁骨下动脉假性动脉瘤(SAP)的血管内治疗,并伴有继发于创伤性中心静脉导管插入的动静脉瘘。从无名处到右颈总动脉展开覆膜支架,结合SAP和乳内动脉的卷绕。另外两个覆膜支架从椎动脉部署到锁骨下动脉远端以保持右上肢循环。此案例强调了在不适合开放手术的候选人中对复杂SAP进行血管内治疗的可行性。
    This report describes the case of a frail 36-year-old patient who underwent an endovascular treatment of a right subclavian artery pseudoaneurysm (SAP) associated with an arteriovenous fistula secondary to a traumatic central venous catheter insertion. The deployment of a covered stent from the innominate to the right common carotid artery combined with coiling of the SAP and the internal mammary artery was performed. Two additional covered stents were deployed from the vertebral artery to the distal subclavian artery to preserve right upper extremity circulation. This case highlights the feasibility of an endovascular treatment of a complex SAP in a candidate unsuitable for open surgery.
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  • 文章类型: Case Reports
    脑膜囊肿(LMC)是小儿颅脑损伤的已知并发症,但除颅骨融合外,在开颅手术后尚未描述。我们介绍了一个20个月大的男孩因外伤性硬膜外血肿接受开颅手术的情况。硬脑膜意外撕裂,并用颅骨修补和硬脑膜密封剂修复。患者在手术后5个月出现进行性手术部位肿胀,CT扫描显示LMC,骨瓣抬高。他接受了硬脑膜缺损的水密修复和骨瓣的刚性固定的重新探索。与更常见的自发性创伤后LMC相比,这种医源性LMC提供了比较和确认发病机理的机会。我们的报告强调了颅骨仍在生长的儿童开颅手术后适当的硬脑膜闭合和骨固定的重要性。
    Leptomeningeal cyst (LMC) is a known complication of pediatric head injury but has not been described following a craniotomy other than for craniosynostosis. We present the case of a 20-month-old boy who underwent craniotomy for a traumatic epidural hematoma. There was an inadvertent tear of the dura which was repaired with a pericranial patch and dural sealant. The patient presented with a progressive surgical site swelling 5 months post-surgery and a CT scan revealed an LMC with elevation of the bone flap. He underwent re-exploration with watertight repair of the dural defect and rigid fixation of the bone flap. This iatrogenic LMC provides an opportunity to compare and confirm the pathogenesis vis a vis the more common spontaneous post-traumatic LMC. Our report highlights the importance of proper dural closure and bone fixation after craniotomy in children whose skulls are still growing.
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  • 文章类型: Journal Article
    越来越多的泌尿生殖系统疾病治疗可导致各种医源性并发症。术后设置的多模态成像对于早期和准确诊断以限制发病率和死亡率至关重要。我们通过基于病例的方法回顾了影响泌尿生殖系统的常见和罕见的治疗引起的病理。我们说明了影响肾脏的明显并发症,输尿管,膀胱,和经皮手术引起的尿道,外部光束辐射,免疫疗法,腹腔镜/机器人骨盆手术,和囊内BCG。最后,我们为最佳影像诊断技术提供指导,并强调影像引导干预在缓解并发症方面的作用.
    A growing number of treatments for genitourinary diseases can result in various iatrogenic complications. Multimodality imaging in the post-procedural setting is essential for early and accurate diagnosis to limit morbidity and mortality. We review common and uncommon treatment-induced pathologies affecting the genitourinary system via a case-based approach. We illustrate notable complications affecting the kidneys, ureters, bladder, and urethra induced by percutaneous procedures, external beam radiation, immunotherapy, laparoscopic/robotic pelvic surgery, and intravesicular BCG. Finally, we provide guidance on optimal imaging techniques for diagnosis and highlight the role of image-guided interventions for mitigation of complications.
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