geographical mapping

地理制图
  • 文章类型: Journal Article
    背景:全国范围内的母婴健康(MCH)服务覆盖率估计掩盖了地区级和社区级的地理不平等现象。这项研究的目的是使用机器学习技术估算尼日利亚基本MCH服务的网格级别覆盖率。
    方法:本研究中的基本MCH服务包括产前护理,基于设施的交付,儿童疫苗接种和儿童疾病的治疗。我们使用2003年至2018年尼日利亚五次国家代表性横断面调查的数据和地理空间社会经济数据,估计了每个基本MCH服务的广义累加模型(GAM)和梯度增强回归(GB)。环境和物理特征。使用每个服务的最佳性能模型,我们绘制了城市和农村地区1平方公里和5平方公里空间分辨率的预测覆盖率,分别。
    结果:在一系列基本MCH服务中,GAM的表现始终优于GB模型,显示较低的系统预测误差。高分辨率地图显示了MCH服务覆盖范围的明显地理差异,特别是在农村和城市地区之间以及不同的州和服务类型之间。时间趋势表明,从2003年到2018年,MCH服务覆盖范围总体增加,尽管服务类型和位置有所不同。确定了孕产妇和疫苗接种服务覆盖率较低的优先领域,大部分位于尼日利亚北部。
    结论:高分辨率空间估计可以指导地理优先级划分,并有助于为实施计划制定更好的策略,允许将有限的资源用于基本妇幼保健服务覆盖率较低的地区。
    BACKGROUND: National-level coverage estimates of maternal and child health (MCH) services mask district-level and community-level geographical inequities. The purpose of this study is to estimate grid-level coverage of essential MCH services in Nigeria using machine learning techniques.
    METHODS: Essential MCH services in this study included antenatal care, facility-based delivery, childhood vaccinations and treatments of childhood illnesses. We estimated generalised additive models (GAMs) and gradient boosting regressions (GB) for each essential MCH service using data from five national representative cross-sectional surveys in Nigeria from 2003 to 2018 and geospatial socioeconomic, environmental and physical characteristics. Using the best-performed model for each service, we map predicted coverage at 1 km2 and 5 km2 spatial resolutions in urban and rural areas, respectively.
    RESULTS: GAMs consistently outperformed GB models across a range of essential MCH services, demonstrating low systematic prediction errors. High-resolution maps revealed stark geographic disparities in MCH service coverage, especially between rural and urban areas and among different states and service types. Temporal trends indicated an overall increase in MCH service coverage from 2003 to 2018, although with variations by service type and location. Priority areas with lower coverage of both maternal and vaccination services were identified, mostly located in the northern parts of Nigeria.
    CONCLUSIONS: High-resolution spatial estimates can guide geographic prioritisation and help develop better strategies for implementation plans, allowing limited resources to be targeted to areas with lower coverage of essential MCH services.
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  • 文章类型: Journal Article
    背景:在温带世界中,莱姆病(LD)是影响人类的最常见的媒介传播疾病。在北美,LD的监视和研究显示,宿主的领土不断扩大,伴随着人类疾病发病率增加的细菌和媒介。为了更好地了解导致疾病传播的因素,预测模型可以使用当前和历史数据来预测人群中跨时间和空间的疾病发生。已经使用了各种预测方法,包括评估预测准确性和/或性能的方法,以及LD风险预测研究中的一系列预测因子。通过这次范围审查,我们的目标是记录不同的建模方法,包括预测和/或预测方法的类型,评估模型性能的预测因子和方法(例如,准确性)。
    方法:本范围审查将遵循系统审查的首选报告项目和范围审查指南的Meta分析扩展。电子数据库将通过关键词和主题词进行搜索(例如,医学主题标题术语)。搜索将在以下数据库中执行:PubMed/MEDLINE,EMBASE,CAB文摘,全球卫生和SCOPUS。以英语或法语报道的研究将通过空间预测和时间预测方法调查人类LD的风险,并进行筛选。资格标准将应用于文章列表,以确定要保留哪些文章。两名审稿人将筛选标题和摘要,然后是文章内容的全文筛选。数据将被提取并绘制成标准形式,合成和解释。
    背景:此范围界定审查基于已发表的文献,不需要伦理批准。研究结果将在同行评审的期刊上发表,并在科学会议上发表。
    BACKGROUND: In the temperate world, Lyme disease (LD) is the most common vector-borne disease affecting humans. In North America, LD surveillance and research have revealed an increasing territorial expansion of hosts, bacteria and vectors that has accompanied an increasing incidence of the disease in humans. To better understand the factors driving disease spread, predictive models can use current and historical data to predict disease occurrence in populations across time and space. Various prediction methods have been used, including approaches to evaluate prediction accuracy and/or performance and a range of predictors in LD risk prediction research. With this scoping review, we aim to document the different modelling approaches including types of forecasting and/or prediction methods, predictors and approaches to evaluating model performance (eg, accuracy).
    METHODS: This scoping review will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Review guidelines. Electronic databases will be searched via keywords and subject headings (eg, Medical Subject Heading terms). The search will be performed in the following databases: PubMed/MEDLINE, EMBASE, CAB Abstracts, Global Health and SCOPUS. Studies reported in English or French investigating the risk of LD in humans through spatial prediction and temporal forecasting methodologies will be identified and screened. Eligibility criteria will be applied to the list of articles to identify which to retain. Two reviewers will screen titles and abstracts, followed by a full-text screening of the articles\' content. Data will be extracted and charted into a standard form, synthesised and interpreted.
    BACKGROUND: This scoping review is based on published literature and does not require ethics approval. Findings will be published in peer-reviewed journals and presented at scientific conferences.
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  • 文章类型: Journal Article
    背景:在卫生系统政策和规划的国际标准中,使用医疗机构类型作为服务可用性的衡量标准是一种常用方法。然而,该代理可能无法准确反映特定卫生服务的实际可用性。
    目的:本研究旨在评估医疗机构类型学作为特定卫生服务可用性指标的可靠性,并探讨某些设施类型是否始终如一地提供特定服务。
    方法:我们分析了一个综合数据集,其中包含来自马里1725个医疗机构的信息。要发现和可视化数据集中的模式,我们使用了两种分析技术:多重对应分析和类间分析。这些分析使我们能够定量测量医疗机构类型对卫生服务供应变化的影响。此外,我们开发并计算了一致性指数,评估医疗机构类型在提供特定卫生服务方面的一致性。通过检查各种卫生设施和服务,我们试图确定设施类型作为服务可用性指标的准确性。
    方法:该研究以马里的卫生系统为案例研究。
    结果:我们的研究结果表明,使用医疗机构类型作为马里服务可用性的代理并不准确。我们观察到,服务提供的大部分差异并非源于设施类型之间的差异,而是源于设施类型之间的差异。这表明,仅依靠医疗机构类型可能会导致对卫生服务可用性的不完全理解。
    结论:这些结果对卫生政策和规划具有重要意义。应重新考虑将卫生设施类型作为卫生系统政策和计划的指标。对卫生服务的可获得性有更细致和基于证据的理解对于有效的卫生政策和规划至关重要,以及卫生系统的评估和监测。
    BACKGROUND: Using health facility types as a measure of service availability is a common approach in international standards for health system policy and planning. However, this proxy may not accurately reflect the actual availability of specific health services.
    OBJECTIVE: This study aims to evaluate the reliability of health facility typology as an indicator of specific health service availability and explore whether certain facility types consistently provide particular services.
    METHODS: We analysed a comprehensive dataset containing information from 1725 health facilities in Mali. To uncover and visualise patterns within the dataset, we used two analytical techniques: Multiple Correspondence Analysis and Between-Class Analysis. These analyses allowed us to quantitatively measure the influence of health facility types on the variation in health service provisioning. Additionally, we developed and calculated a Consistency Index, which assesses the consistency of a health facility type in providing specific health services. By examining various health facilities and services, we sought to determine the accuracy of facility types as indicators of service availability.
    METHODS: The study focused on the health system in Mali as a case study.
    RESULTS: Our findings indicate that using health facility types as a proxy for service availability in Mali is not an accurate representation. We observed that most of the variation in service provision does not stem from differences between facility types but rather within facility types. This suggests that relying solely on health facility typology may lead to an incomplete understanding of health service availability.
    CONCLUSIONS: These results have significant implications for health policy and planning. The reliance on health facility types as indicators for health system policy and planning should be reconsidered. A more nuanced and evidence-based understanding of health service availability is crucial for effective health policy and planning, as well as for the assessment and monitoring of health systems.
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  • 文章类型: Journal Article
    目的:及时获得安全和负担得起的手术对于全民健康覆盖至关重要。迄今为止,没有研究评估2小时接受Bellwether手术(剖腹产,剖腹手术,菲律宾的开放性骨折管理)。这项研究的目的是测量菲律宾能够在2小时内到达领头羊医院的人口比例,并确定该国手术服务最不足的地区。
    方法:所有具有领头羊能力的公立医院均来自菲律宾卫生部网站。ArcGISPro中的服务区域工具用于确定Bellwether设施2小时车程内的人口。最后,进行了适宜性建模,以确定针对菲律宾服务最薄弱地区的外科设施的潜在未来地点。
    结果:确定了428家具有领头羊能力的医院。85.1%的人口在其中一个设施的2小时内居住。然而,6个地区的人口不到80%的人口生活在具有领头羊能力的设施的2小时内:Bicol,东米沙亚,三宝颜,棉兰老岛穆斯林自治区,Caraga和Mimaropa.适宜性分析确定了四个区域-卡拉加,Mimaropa,卡拉巴松和三宝颜是建立具有手术能力的新医院的理想地点,可以提高接诊率。
    结论:菲律宾85.1%的人口能够在2小时内到达具有领头羊能力的医院,在接入率方面存在地区差异。然而,其他因素,如天气,交通状况,金融准入,还应考虑24小时手术服务的可用性和使用机动车辆的机会,因为它们也会影响实际的访问率。
    Timely access to safe and affordable surgery is essential for universal health coverage. To date, there are no studies evaluating 2-hour access to Bellwether procedures (caesarean section, laparotomy, open fracture management) in the Philippines. The objectives of this study were to measure the proportion of the population able to reach a Bellwether hospital within 2 hours in the Philippines and to identify areas in the country with the most surgically underserved populations.
    All public hospitals with Bellwether capacities were identified from the Philippines Ministry of Health website. The service area tool in ArcGIS Pro was used to determine the population within a 2-hour drive time of a Bellwether facility. Finally, suitability modelling was conducted to identify potential future sites for a surgical facility that targets the most underserved regions in the Philippines.
    428 Bellwether capable hospitals were identified. 85.1% of the population lived within 2 hours of one of these facilities. However, 6 regions had less than 80% of its population living within 2 hours of a Bellwether capable facility: Bicol, Eastern Visayas, Zamboanga, Autonomous region of Muslim Mindanao, Caraga and Mimaropa. Suitability analysis identified four regions-Caraga, Mimaropa, Calabarzon and Zamboanga-as ideal locations to build a new hospital with surgical capacity to improve access rates.
    85.1% of the population of the Philippines are able to reach Bellwether capable hospitals within 2 hours, with regional disparities in terms of access rates. However, other factors such as weather, traffic conditions, financial access, availability of 24-hour surgical services and access to motorised vehicles should also be taken into consideration, as they also affect actual access rates.
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  • 文章类型: Journal Article
    目的:我们的目标是探索撒哈拉以南非洲(SSA)在不同地理尺度的艾滋病毒检测中社会经济不平等的空间变化,以确定不平等的潜在地理热点。此外,评估艾滋病毒检测计划的潜在好处,我们评估当地的HIV检测水平是否与当地的HIV流行水平相匹配.
    方法:对SSA中基于人口的横断面调查的多国家分析。
    方法:我们分析了2011年至2019年25个SSA国家的人口与健康调查数据。
    方法:国家层面的分析包括473775名参与者(312104名女性和161671名男性),集群层面的分析包括328283名个体(241084名女性和87199名男性)。在过去12个月内接受艾滋病毒检测的选定家庭中,年龄在15-49岁的女性和年龄在15-54/59岁的男性符合资格。我们使用地理尺度上的不平等斜率指数(SII)和不平等相对指数(RII)对自我报告的最近HIV测试中的不平等进行了量化,以捕获特定性别的国内空间变化。我们还进行了本地Getis-OrdGi*统计,以考虑各国精细SII和RII的自相关。评估艾滋病毒检测计划的效率,我们通过跨地理尺度的Spearman相关性测量了近期HIV检测与HIV患病率之间的相关性.
    结果:我们观察到,在许多国家,在国家和国家以下各级,男女在绝对和相对尺度上,最近的艾滋病毒检测在幅度和空间分布上存在不同的不平等。绝对和相对不平等的热点主要出现在西非和中非以及东部和南部非洲的一些地区。尽管在国家一级评估时,所有国家的检测和流行率之间存在显著的性别特异性相关性,我们报告50个性别-国家组合中的17个在精细尺度上没有这种相关性.
    结论:我们强调了在不同地理水平上调查各种HIV指标的空间变异性和相关不平等的重要性。结果可能有助于公平分配艾滋病毒检测服务。
    We aim to explore spatial variations in socioeconomic inequalities in HIV testing uptake in sub-Saharan Africa (SSA) at different geographical scales to identify potential geographical hotspots of inequalities. Additionally, to evaluate the potential benefits of HIV testing programmes, we assess whether local levels of HIV testing match the local levels of HIV prevalence.
    A multi-country analysis of population-based cross-sectional surveys in SSA.
    We analysed data from 25 SSA countries with Demographic and Health Surveys between 2011 and 2019.
    Country-level analysis included 473 775 participants (312 104 women and 161 671 men) and cluster-level analysis included 328 283 individuals (241 084 women and 87 199 men). Women aged 15-49 years and men aged 15-54/59 years in selected households who were tested for HIV in the last 12 months were eligible. We quantified inequalities in self-reported recent HIV testing with the Slope Index of Inequality (SII) and the Relative Index of Inequality (RII) across geographical scales to capture sex-specific within-country spatial variations. We also conducted local Getis-Ord Gi* statistics to consider the autocorrelation in fine-scale SII and RII across countries. To assess the efficiency of HIV testing programmes, we measured the correlation between recent HIV testing and HIV prevalence through Spearman correlation across geographical scales.
    We observed varying inequalities in recent HIV testing in magnitude and spatial distribution on both absolute and relative scales in many countries for both sexes at national and subnational levels. Hotspots of absolute and relative inequalities were mostly observed in Western and Central Africa with a few regions in Eastern and Southern Africa. Despite significant sex-specific correlations between testing and prevalence in all countries when assessed at the national level, we report an absence of such a correlation at fine scale in 17 of 50 sex-country combinations.
    We highlight the importance of investigating the spatial variability of various HIV indicators and related inequalities across different geographical levels. Results may help inform an equitable distribution of HIV testing services.
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  • 文章类型: Journal Article
    背景:个人健康的风险应与环境一起考虑,他们生活的社会文化和社会政治背景。环境制图是一种确定社区内健康的推动者和障碍的方法。土著指标分类系统(IICS)框架已用于绘制澳大利亚土著社区的环境图。IICS是一个四级嵌套分层框架,主题组包括文化,社会政治,建立在层次结构的顶部,指标在底部。这次范围审查的目的是绘制文化地图,社会政治,环境和建筑资产,支持每个托雷斯海峡岛社区存在的健康和福祉。
    方法:此审查将根据JoannaBriggsInstitute(JBI)用于范围审查的方法进行。它将包括识别文化的来源,社会政治,环境和建筑资产,支持每个托雷斯海峡岛社区存在的健康和福祉。要搜索的数据库包括:Informit;Scopus;WebofScience;HealthInfoNet,BioOne完整和绿色文件。未出版和灰色文献的来源将使用Google和GoogleScholar进行定位。搜索将仅限于自2018年1月以来发布的英语语言和文献,以确保绘制的资产反映每个岛屿的当前状况。回答研究问题的数据将从来源中提取,并记录在IICS的改编中。数据的定量分析将包括对各个岛屿及其相关集群的每个资产进行求和。数据将以图形方式呈现,图解,或以表格形式,取决于哪种方法最能传达其含义。
    背景:远北昆士兰人类研究伦理委员会(参考HREC/2022/QCH/88155-1624)已批准本研究。研究小组的托雷斯海峡岛民成员将通过会议和同行评审的出版物来领导审查结果的传播。
    Risks to an individual\'s health should be considered alongside the environmental, sociocultural and sociopolitical context(s) in which they live. Environmental mapping is an approach to identifying enablers and barriers to health within a community. The Indigenous Indicator Classification System (IICS) framework has been used to map the environment in Australian Indigenous communities. The IICS is a four-level nested hierarchical framework with subject groups including culture, sociopolitical and built at the top of the hierarchy and indicators at the bottom. The objective of this scoping review is to map the cultural, sociopolitical, environmental and built assets that support health and well-being that exist in each Torres Strait Island community.
    This review will be conducted according the Joanna Briggs Institute (JBI) method for scoping reviews. It will include sources that identify cultural, sociopolitical, environmental and built assets that support health and well-being that exist in each Torres Strait Island community. Databases to be searched include: Informit; Scopus; Web of Science; HealthInfoNet, BioOne Complete and Green File. Sources of unpublished and grey literature will be located using Google and Google Scholar. Searches will be limited to the English language and literature published since January 2018 to ensure that the assets mapped reflect current conditions on each island. Data that answers the research question will be extracted from sources and recorded in an adaptation of the IICS. Quantitative analysis of the data will include summing each asset for individual islands and their associated clusters. Data will be presented graphically, diagrammatically, or in tabular form depending on what approach best conveys its meaning.
    The Far North Queensland Human Research Ethics Committee (reference HREC/2022/QCH/88 155-1624) has approved this study. Dissemination of the review\'s findings will be led by Torres Strait Islander members of the research team through conferences and peer-reviewed publications.
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  • 文章类型: Journal Article
    建立网络是促进健康的重要组成部分。然而,网络分析在这一领域仍然相对未被探索。这项研究引入了一种新技术,可以绘制主题议程和健康促进行为者的地理位置。
    本案例研究使用定量和定性方法来分析网络数据。我们使用了来自巴伐利亚两个网络的经验数据,德国的联邦州。
    我们在第一个网络中确定了总共55个参与者,在第二个网络中确定了64个参与者。我们根据参与者的主要工作领域对他们的主题议程进行了分类:“健康的儿童发展,“健康的中年阶段,“健康老龄化,生命各个阶段的健康公平。“一个网络显示,关注健康老龄化的参与者大量过剩。“我们将来自两个网络的数据进行了汇总和分析。确定了两个在其地理边界内没有健康促进行为者的地区。为了将地理差距纳入背景,包括有关剥夺和年龄的数据。
    结果确定了需要健康促进行为者支持的地理区域。通过将我们的结果与现有文献进行比较,我们得出了进一步成功建立网络的潜在网络策略。这项研究增加了一个新的视角,通过在主题和地理上绘制健康促进网络来表征它们。该概念可用于为健康促进组织提供对网络结构的相关见解。这可以改善有关伙伴关系战略的决策过程,并最终产生积极的健康影响。因此,我们的研究结果鼓励这一技术和其他网络方法在健康公平和健康促进领域的进一步发展.
    Building networks is an essential part of health promotion. However, network analysis remains relatively unexplored in this field. This study introduces a new technique that maps thematic agendas and geographical locations of health promotion actors.
    This case study used elements of quantitative and qualitative methods to analyse network data. We used empirical data from two networks in Bavaria, a federal state of Germany.
    We identified a total of 55 actors in the first network and 64 actors in the second. We categorized the thematic agenda of actors according to their main field of work: \"healthy childhood development,\" \"healthy middle age phase,\" \"healthy ageing,\" \"health equity in all phases of life.\" One network showed a significant surplus of actors that focus on \"healthy ageing.\" We combined and analysed data from both networks collectively. Two districts with no health promotion actors within their geographical borders were identified. To put geographical gaps into context, data about deprivation and age was included.
    Results identified geographical areas with high need for support from health promotion actors. Through comparison of our results with existing literature, we derived potential network strategies for further successful networking. This study adds a new perspective to characterize health promotion networks by mapping them thematically and geographically. The concept can be used to give health promotion organisations relevant insight into network structures. This can improve decision-making processes concerning partnership strategy and finally lead to a positive health impact. Hence, our findings encourage further development of this technique and other networking methods in the field of health equity and health promotion.
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  • 文章类型: Journal Article
    目的:该研究将印度开放性排便(OD)的空间异质性和相关驱动因素进行了研究。
    方法:本研究涉及印度2019-2021年进行的第五轮全国家庭健康调查的二级横断面调查数据。我们使用LISA聚类技术绘制了OD实践的空间异质性,并使用多元回归模型评估了OD的关键驱动因素。使用Fairlie分解模型来识别导致OD热点和冷点发展的因素。
    方法:该研究是在印度进行的,包括印度707个地区的36个州和联邦领土内的636699个抽样家庭。
    方法:结果测量是OD的患病率。
    结果:OD的患病率几乎是20%,热点地区主要位于该国中北部地带。农村-城市(26%对6%),文盲-受过高等教育(32%对4%)和穷人-富人(52%对2%)的OD差距非常高。在农村地区和没有供水服务的家庭中,OD的几率分别是同类家庭的2.7倍和1.9倍。空间误差模型将不识字的家庭(系数=0.50,p=0.001)确定为OD的主要空间联系预测因子,其次是最差的(系数=0.31,p=0.001)和印度教(系数=0.10,p=0.001)。OD的高低簇不平等为38%,家庭财富五分之一(67%)被认为是最重要的贡献因素,其次是宗教(22.8%)和教育水平(6%)。
    结论:OD的做法集中在印度的中北部地区,尤其是穷人,文盲和社会落后的群体。应采取政策措施改善卫生做法,特别是在重点地区和弱势群体中,通过采用多光谱和多部门方法。
    The study contextualises the spatial heterogeneity and associated drivers of open defecation (OD) in India.
    The present study involved a secondary cross-sectional survey data from the fifth round of the National Family Health Survey conducted during 2019-2021 in India. We mapped the spatial heterogeneity of OD practices using LISA clustering techniques and assessed the critical drivers of OD using multivariate regression models. Fairlie decomposition model was used to identify the factors responsible for developing OD hot spots and cold spots.
    The study was conducted in India and included 636 699 sampled households within 36 states and union territories covering 707 districts of India.
    The outcome measure was the prevalence of OD.
    The prevalence of OD was almost 20%, with hot spots primarily located in the north-central belts of the country. The rural-urban (26% vs 6%), illiterate-higher educated (32% vs 4%) and poor-rich (52% vs 2%) gaps in OD were very high. The odds of OD were 2.7 and 1.9 times higher in rural areas and households without water supply service on premises compared with their counterparts. The spatial error model identified households with an illiterate head (coefficient=0.50, p=0.001) as the leading spatially linked predictor of OD, followed by the poorest (coefficient=0.31, p=0.001) and the Hindu (coefficient=0.10, p=0.001). The high-high and low-low cluster inequality in OD was 38%, with household wealth quintile (67%) found to be the most significant contributing factor, followed by religion (22.8%) and level of education (6%).
    The practice of OD is concentrated in the north-central belt of India and is particularly among the poor, illiterate and socially backward groups. Policy measures should be taken to improve sanitation practices, particularly in high-focus districts and among vulnerable groups, by adopting multispectral and multisectoral approaches.
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  • 文章类型: Journal Article
    目标:在低收入/中等收入国家,维生素A缺乏影响到所有5岁以下儿童的估计29%。导致儿童死亡率和加重感染的严重程度。对于6-59个月的儿童,每半年补充维生素A(VAS)可以是满足维生素A需求的低成本干预措施。这项研究旨在提供一个框架,用于根据已知影响儿童营养的决定因素评估国家VAS计划的公平层面,并通过强调覆盖范围的地理差异来协助计划。
    方法:我们使用了来自49个国家的人口与健康调查的开源数据,以确定不同即时数据特征的亚人群之间的VAS覆盖率差异。维生素A状况和地理上的潜在和有利决定因素。这包括最近食用富含维生素A的食物,获得卫生系统和服务,国家行政区域,居住地(农村vs城市),社会经济地位,护理人员教育程度和护理人员赋权。
    结果:在大多数国家,最近没有食用富含维生素A的食物以及获得卫生系统和服务的机会较差的儿童接受VAS的可能性较小,尽管可能有更大的维生素A需求。按行政区(88%的国家)和城市与农村居住地(35%的国家)分类时,也观察到了覆盖率的差异。以维生素A状况的其他决定因素为特征的亚群之间的维生素A覆盖率差异很大。
    结论:VAS计划无法覆盖所有符合条件的婴儿和儿童,以维生素A状况的各种决定因素为特征的VAS覆盖率的亚种群差异表明,在许多国家,VAS计划可能无法公平运行。
    Vitamin A deficiency affects an estimated 29% of all children under 5 years of age in low/middle-income countries, contributing to child mortality and exacerbating severity of infections. Biannual vitamin A supplementation (VAS) for children aged 6-59 months can be a low-cost intervention to meet vitamin A needs. This study aimed to present a framework for evaluating the equity dimensions of national VAS programmes according to determinants known to affect child nutrition and assist programming by highlighting geographical variation in coverage.
    We used open-source data from the Demographic and Health Survey for 49 countries to identify differences in VAS coverage between subpopulations characterised by various immediate, underlying and enabling determinants of vitamin A status and geographically. This included recent consumption of vitamin A-rich foods, access to health systems and services, administrative region of the country, place of residence (rural vs urban), socioeconomic position, caregiver educational attainment and caregiver empowerment.
    Children who did not recently consume vitamin A-rich foods and who had poorer access to health systems and services were less likely to receive VAS in most countries despite potentially having a greater vitamin A need. Differences in coverage were also observed when disaggregated by administrative regions (88% of countries) and urban versus rural residence (35% of countries). Differences in vitamin A coverage between subpopulations characterised by other determinants of vitamin A status varied considerably between countries.
    VAS programmes are unable to reach all eligible infants and children, and subpopulation differences in VAS coverage characterised by various determinants of vitamin A status suggest that VAS programmes may not be operating equitably in many countries.
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  • 文章类型: Journal Article
    Limited monitoring data are available regarding the occurrence of emerging per- and polyfluoroalkyl substances (PFAS) in drinking water. Here, we validated an analytical procedure for 42 PFAS with individual detection limits of 0.001-0.082 ng/L. We also evaluated how different sample pH conditions, dechlorinating agents, and storage holding times might affect method performance. PFAS were analyzed in tap water samples collected at a large spatial scale in Quebec, Canada, covering 376 municipalities within 17 administrative regions. Target and nontarget screening revealed the presence of 31 and 23 compounds, respectively, representing 24 homolog classes. Overall, 99.3% of the tap water samples were positive for at least one PFAS, and the ƩPFAS ranged from below detection limits to 108 ng/L (95th percentile: 13 ng/L). On average, ƩPFAS was 12 times higher in tap water produced from surface water than groundwater; however, 6 of the top 10 contaminated locations were groundwater-based. Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) had high detection rates (88% and 80%, respectively). PFOS (median: 0.15 ng/L; max: 13 ng/L) and PFOA (median: 0.27 ng/L; max: 8.1 ng/L) remained much lower than current Health Canada guidelines but higher than USEPA\'s interim updated health advisories. Short-chain (C3-C6) perfluoroalkyl sulfonamides were also recurrent, especially the C4 homolog (FBSA: detection rate of 50%). The 6:2 fluorotelomer sulfonyl propanoamido dimethyl ethyl sulfonate (6:2 FTSO2PrAd-DiMeEtS) was locally detected at ∼15 ng/L and recurred in 8% of our samples. Multiple PFAS that are most likely to originate from aqueous film-forming foams were also reported for the first time in tap water, including X:3 and X:1:2 fluorotelomer betaines, hydroxylated X:2 fluorotelomer sulfonates, N-trimethylammoniopropyl perfluoroalkane sulfonamides (TAmPr-FHxSA and TAmPr-FOSA), and N-sulfopropyl dimethylammoniopropyl perfluoroalkane sulfonamidopropyl sulfonates (N-SPAmP-FPeSAPS and N-SPAmP-FHxSAPS).
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