背景:传染性软疣(MC)是由痘病毒引起的皮肤病毒感染,表现为离散,丘疹,珠状病变伴中央脐带化。生殖器病变主要通过性传播。直到日期,已经使用了几种形式的医学和外科疗法,取得了不同的成功。在本研究中,尝试审查所有在皮肤科性传播感染(STI)诊所就诊的生殖器MC女性患者,性病,和GuruNanakDev医院的麻风病,阿姆利则.
目的:在本研究中,对局部使用10%和20%氢氧化钾(KOH)的疗效和对比评价进行了研究.
方法:本研究共纳入30名18-50岁年龄段的女性患者,临床诊断为MC和10个以上病变。将每位患者的病变分为A和B两个相等的组。在26G针的帮助下,在A组的病变上局部应用10%KOH,在B组的病变上局部应用20%KOH。首先,医生做了两次申请,随后的应用每周两次,由患者自己在家睡觉,直到结痂。这些病例在第4天随访,1st,2nd,3rd,第四,6th,8th,第十,第12周。在每次随访和研究结束时,对结果进行客观和照相分析。
结果:正常患者的平均治疗时间±标准差,HIV阳性患者,有相关性传播感染的患者,患有相关非性传播感染的患者,A组和B组孕妇分别为6.83±2.692、9.33±1.633、6.83±2.887、8.20±3.347和8.75±2.121周和5.2±2.156、7.33±1.633、5.25±2.050、6.20±2.864和6.50±1.414周,分别。
结论:外用20%KOH治疗女性生殖器MC优于10%KOH。
BACKGROUND: Molluscum contagiosum (MC) is a cutaneous viral infection caused by a poxvirus, manifested by discrete, papular, pearly lesions with central umbilication. Genital lesions are mainly transmitted sexually. Till date, several forms of medical and surgical therapies have been used with variable success. In the present study, an attempt was made to review all the female patients of genital MC attending the sexually transmitted infection (STI) clinic of the Department of Dermatology, Venereology, and Leprosy of Guru Nanak Dev Hospital, Amritsar.
OBJECTIVE: In the present study, therapeutic efficacy and comparative evaluation of topical 10% and 20% of potassium hydroxide (KOH) were undertaken.
METHODS: A total of 30 female patients of age group 18-50 years with clinically diagnosed MC and more than ten lesions were enrolled in this study. The lesions in each patient were divided into two equal Groups A and B. Topical 10% KOH was applied over lesions of Group A and 20% over lesions of Group B with the help of 26G needle. First, two applications were done by the doctor, and subsequent applications were done twice a week at bedtime at home by the patient herself until crusting. These cases were followed up at 4th day, 1st, 2nd, 3rd, 4th, 6th, 8th, 10th, and 12th week. Results were analyzed objectively and photographically at each follow-up and at the end of the study statistically.
RESULTS: Mean duration of treatment ± standard deviation in normal patients, HIV-positive patients, patients with associated STIs, patients with associated non-STIs, and pregnant patients in Group A and Group B was 6.83 ± 2.692, 9.33 ± 1.633, 6.83 ± 2.887, 8.20 ± 3.347, and 8.75 ± 2.121 weeks and 5.2 ± 2.156, 7.33 ± 1.633, 5.25 ± 2.050, 6.20 ± 2.864, and 6.50 ± 1.414 weeks, respectively.
CONCLUSIONS: Topical 20% KOH is better than 10% KOH in genital MC in females.