关键词: Autoinoculation genital molluscum contagiosum molluscum contagiosum

来  源:   DOI:10.4103/ijstd.ijstd_102_22   PDF(Pubmed)

Abstract:
UNASSIGNED: Molluscum contagiosum (MC) typically presents as asymptomatic or itchy, discrete, smooth, flesh-colored, dome-shaped papules with central umbilication. Lesions on the genitals are often sexually transmitted and tend to be seen in young adults. Homologous auto implantation is a simple technique which helps in inducing a cell-mediated immune response to the antigens, aiding clearance of both local and distant lesions.
UNASSIGNED: The aim of the study is to evaluate the efficacy and side effect of the technique of autoinoculation for the treatment of genital MC in terms of reduction in number of lesions.
UNASSIGNED: Thirty-one patients having >5 genital molluscum attending skin outpatient department were enrolled out of which 30 remain. A well-defined mc lesion was approached using an insulin syringe (30 G) and pierced from a site just adjacent to the lesion. Results were assessed every 2 weeks for 2 months.
UNASSIGNED: 60% (n = 18) patients showed excellent response, 20% (n = 6) patients showed very good response, 6.6% (n = 2) patients showed good response and 13.3% (n = 4) showed poor response at the end of the study.
UNASSIGNED: The autoinoculation technique is an effective technique in terms of excellent clearance of MC lesions with fewer chances of recurrence, side effects, and shorter duration taken to achieve a complete response to distant lesions.
摘要:
传染性软疣(MC)通常表现为无症状或发痒,离散,光滑,肉色的,圆顶状的丘疹具中央脐状。生殖器上的病变通常是性传播的,并且倾向于在年轻人中看到。同源自体植入是一种简单的技术,有助于诱导对抗原的细胞介导的免疫反应。帮助清除局部和远处的病变。
该研究的目的是评估自体接种技术在减少病变数量方面治疗生殖器MC的功效和副作用。
招募了31名在皮肤门诊就诊的生殖器软体动物>5例的患者,其中30例仍然存在。使用胰岛素注射器(30G)接近明确定义的mc病变,并从病变附近的部位刺穿。结果每2周评估一次,为期2个月。
60%(n=18)的患者表现出极好的反应,20%(n=6)患者表现出非常好的反应,在研究结束时,6.6%(n=2)的患者表现出良好的反应,而13.3%(n=4)的患者表现出不良的反应。
自动接种技术是一种有效的技术,可以出色地清除MC病变,并且复发的机会更少,副作用,和较短的持续时间,以实现对远处病变的完全反应。
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