背景:在注意缺陷/多动障碍(ADHD)中,抑制性控制不良是其主要特征之一,眼球运动抑制受损被认为是该疾病的潜在生物标志物。虽然听觉白噪声已经证明了在这个群体中增强工作记忆的能力,视觉白噪声仍未被探索,两种类型的白噪声刺激对动眼抑制的影响也是如此。
目的:这项交叉研究旨在探讨听觉和视觉白噪声对ADHD儿童和典型发育(TD)儿童动眼抑制的影响。该研究将调查不同噪声水平的影响(25%和50%的视觉,78dB听觉),和性能将在有和没有噪声刺激的情况下进行评估。我们假设暴露于白噪声会改善多动症儿童的表现,并损害TD儿童的表现。
方法:记忆引导扫视和长时间注视,以检测ADHD中动眼神经抑制的敏感性而闻名,将用于评估性能。被诊断患有多动症的儿童,停药24小时,并招募了没有精神疾病的TD儿童进行研究。
结果:数据收集于2023年10月启动,并于2024年2月结束。共有97名参与者报名参加,第一个结果预计在2024年9月至11月之间。
结论:这项研究将检查跨模态感觉刺激是否可以增强执行功能,特别是眼球运动控制,患有ADHD的儿童。此外,这项研究将探讨两组听觉和视觉噪声效应之间的潜在差异。我们的目标是确定理解如何使用噪声来提高认知能力的含义。
背景:ClinicalTrials.govNCT06057441;https://clinicaltrials.gov/study/NCT06057441。
■DERR1-10.2196/56388。
BACKGROUND: In attention-deficit/hyperactivity disorder (ADHD), poor inhibitory control is one of the main characteristics, with oculomotor inhibition impairments being considered a potential biomarker of the disorder. While auditory white noise has demonstrated the ability to enhance working memory in this group, visual white noise is still unexplored and so are the effects of both types of white noise stimulation on oculomotor inhibition.
OBJECTIVE: This crossover study aims to explore the impact of auditory and visual white noise on oculomotor inhibition in children with ADHD and typically developing (TD) children. The study will investigate the impact of different noise levels (25% and 50% visual, 78 dB auditory), and performance will be evaluated both with and without noise stimulation. We hypothesize that exposure to white noise will improve performance in children with ADHD and impair the performance for TD children.
METHODS: Memory-guided saccades and prolonged fixations, known for their sensitivity in detecting oculomotor disinhibition in ADHD, will be used to assess performance. Children diagnosed with ADHD, withdrawing from medication for 24 hours, and TD children without psychiatric disorders were recruited for the study.
RESULTS: Data collection was initiated in October 2023 and ended in February 2024. A total of 97 participants were enrolled, and the first results are expected between September and November 2024.
CONCLUSIONS: This study will examine whether cross-modal sensory stimulation can enhance executive function, specifically eye movement control, in children with ADHD. In addition, the study will explore potential differences between auditory and visual noise effects in both groups. Our goal is to identify implications for understanding how noise can be used to improve cognitive performance.
BACKGROUND: ClinicalTrials.gov NCT06057441; https://clinicaltrials.gov/study/NCT06057441.
UNASSIGNED: DERR1-10.2196/56388.