从陈年的普通鼠尾草渗出物和糖(ACSE)的汁液中分离出19种化合物,包括一种新的黄烷酮。通过NMR和MS分析鉴定分离的化合物为左旋多巴甲酯(1),3,4-二羟基苯甲酸(2),(S)-8-羟基-4-羟基-苯基丙酸(3),4-羟基苯甲酸乙酯(4),顺式咖啡酸(5),反式咖啡酸(6),esculetin(7),(S)-8-羟基-3,4-二羟基-苯基丙酸乙酯(8),顺式迷迭香酸(9),反式迷迭香酸(10),反迷迭香酸甲酯(11),6-甲氧基-7,8,3\',5'-四羟基黄烷酮(12),Nepetin(13),反式咖啡酸乙酯(14),木犀草素(15),顺式咖啡酸乙酯(16),6-甲氧基柚皮素(17),1α-乙酰氧基-2-氧代-Eudesman-3,7(11)-dien-8β,12-内酯(18),和hispidulin(19)。化合物12为首次从自然界中分离得到,7个化合物(1、3、4、7、8、14和18)为新鉴定的化合物。其中,在ACSE果汁中检测到15种分离的酚类化合物(1-3、5-8、10-15、17和19),而在新鲜的普通鼠尾草中只检测到10只。
Nineteen compounds including one new flavanone were isolated from the juice of aged common sage exudate with sugar (ACSE). The isolated compounds were identified by NMR and MS analyses as levodopa methyl ester (1), 3,4-dihydroxybenzoic acid (2), (S)-8-hydroxy-4-hydroxy-phenylpropanoic acid (3), 4-hydroxybenzoic acid ethyl ester (4), cis-caffeic acid (5), trans-caffeic acid (6), esculetin (7), (S)-8-hydroxy-3,4-dihydroxy-phenylpropanoic acid ethyl ester (8), cis-rosmarinic acid (9), trans-rosmarinic acid (10), trans-rosmarinic acid methyl ester (11), 6-methoxy-7,8,3\',5\'-tetrahydroxyflavanone (12), nepetin (13), trans-caffeic acid ethyl ester (14), luteolin (15), cis-caffeic acid ethyl ester (16), 6-methoxynaringenin (17), 1α-acetoxy-2-oxo-eudesman-3,7(11)-dien-8β,12-olide (18), and hispidulin (19). Compound 12 was isolated for the first time from nature and seven compounds (1, 3, 4, 7, 8, 14, and 18) were newly identified from common sage. Of them, 15 isolated phenolic compounds (1-3, 5-8, 10-15, 17, and 19) were detected in ACSE juice, while only 10 was detected in the fresh common sage.