enostosis

enostosis
  • 文章类型: Journal Article
    小儿良性骨肿瘤包括骨瘤,enostosis,骨样骨瘤,和骨母细胞瘤。在儿科人群中,良性骨肿瘤比恶性肿瘤更常见。良性骨细胞肿瘤可能具有独特的临床表现,有助于缩小鉴别诊断范围。应使用系统成像方法来达到诊断并指导临床医生进行管理。射线照片是最普遍和最具成本效益的成像模式。横截面成像可用于组织表征和评估涉及复杂解剖区域(例如骨盆和脊柱)的病变。计算机断层扫描(CT)是诊断骨样骨瘤的首选方式。CT扫描也可用于指导射频消融,已发现其在治疗骨样骨瘤和成骨细胞瘤方面非常有效。结瘤是一种非接触病变。骨瘤通常位于鼻旁窦。如果骨瘤由于质量效应而引起并发症,则需要切除。
    Pediatric benign osteocytic tumors include osteoma, enostosis, osteoid osteoma, and osteoblastoma. In pediatric populations, benign bone tumors are more common than malignancies. Benign osteocytic tumors may have a unique clinical presentation that helps narrow the differential diagnosis. A systemic imaging approach should be utilized to reach the diagnosis and guide clinicians in management. Radiographs are the most prevalent and cost-effective imaging modality. Cross-sectional imaging can be utilized for tissue characterization and for evaluation of lesions involving complex anatomical areas such as the pelvis and spine. Computed Tomography (CT) is the modality of choice for diagnosis of osteoid osteoma. CT scan can also be utilized to guide radiofrequency ablation, which has been found to be highly effective in treating osteoid osteoma and osteoblastoma. Enostosis is a no-touch lesion. Osteoma is commonly located in the paranasal sinuses. Osteoma needs an excision if it causes complications due to a mass effect.
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  • 文章类型: Case Reports
    骨岛(BI;烯酮)可能是孤立的或发生在骨质疏松(多个骨岛)的背景下,有时与Gardner综合征(骨质疏松和结肠息肉病)相关。骨岛的特征是(1)没有疼痛或局部压痛,(2)典型的无线电密集的中心外观,外围辐射针状(玫瑰刺),(3)平均CT(计算机断层扫描)衰减值高于885Hounsfield单位(HU)(4)在骨扫描中没有摄取和(5)随时间的射线照相稳定性。然而,当结骨显示出非典型的疼痛特征时,不寻常的射线照相外观,异常的HU,增加的放射性示踪剂摄取,和/或扩大,它们可能很难与更险恶的骨性病变区分开来,如成骨细胞转移,低级中央骨肉瘤,骨样骨瘤和骨母细胞瘤。在这个回顾性案例系列中,人口统计,临床,射线照相,介绍了10例具有11个非典型骨岛(ABI)的患者的治疗和结果,一些显示相关的疼痛(5),有些具有非典型的射线照相外观(3),一些在BS上的活性增加(4),一些随着时间的推移有记录的扩大(7),一个异常的CT衰减值,一些在骨质疏松的背景下(2),一个在加德纳综合症的背景下,一个模拟骨岛的骨样骨瘤。这个系列代表了ABI的表现谱。对文献的综合回顾表明,先前最大的ABI系列表现为非典型特征的增大是在较年轻的下颌BI患者中。因此,这是成人所有类型ABI报告的最大系列之一.
    Bone islands (BI; enostoses) may be solitary or occur in the setting of osteopoikilosis (multiple bone islands) and are sometimes associated with Gardner\'s Syndrome (osteopoikilosis and colonic polyposis). Characteristic features of bone islands are (1) absence of pain or local tenderness, (2) typical radio dense central appearance with peripheral radiating spicules (rose thorn), (3) Mean CT (computerized tomography) attenuation values above 885 Hounsfield units (HU) (4) absence of uptake on bone scan and (5) radiographic stability over time. However, when enostoses display atypical features of pain, unusual radiographic appearance, aberrant HU, increased radiotracer uptake, and/or enlargement, they can be difficult to differentiate from more sinister bony lesions such as osteoblastic metastasis, low grade central osteosarcoma, osteoid osteoma and osteoblastoma. In this retrospective case series, the demographic, clinical, radiographic, treatment and outcome for ten patients with eleven atypical bone islands (ABI) are presented, some showing associated pain (5), some with atypical radiographic appearance (3), some with increased activity on BS (4), some with documented enlargement over time (7), one with abnormal CT attenuation value, some in the setting of osteopoikilosis (2), one in the setting of Gardner\'s Syndrome and one osteoid osteoma simulating a bone island. This series represents the spectrum of presentations of ABI. Comprehensive review of the literature reveals that the previous largest series of ABI showing enlargement as the atypical feature was in younger patients with jaw BI. Hence, this represents one of the largest series reported of ABI of all types in adults.
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  • 文章类型: Case Reports
    致密骨岛(DBIs)通常无症状,不需要任何治疗。此病例报告提供了一个不寻常的DBI,这是一名15岁正畸患者的X光片上偶然发现的。DBI病灶大小为24mm,占据右上犬齿和侧切牙之间至少50%的肺泡突,向上延伸右鼻窝前缘的外侧。一般来说,DBIs的大小为2-3毫米,更常见于磨牙和前磨牙区域的下颌骨中。本文进一步讨论了DBI对正畸治疗的影响,例如难以实现空间闭合和足够的根尖或扭矩。我们还研究了DBI的潜在医学意义。这在临床上很重要,特别是如果有多个DBI,或与DBIs具有相似影像学表现的骨瘤,在患者中发现,因为它们可能与腺瘤性肠息肉有关,which,如果不治疗,有100%的机会变成恶性转化.
    Dense bone islands (DBIs) are usually asymptomatic and do not require any treatment. This case report presents a DBI of an unusual presentation, which was an incidental finding on a radiograph of a 15-year-old orthodontic patient. The DBI lesion was 24 mm in size, occupying at least 50% of the alveolar process between the upper right canine and lateral incisor, extending up the lateral aspect of the anterior margin of the right nasal fossa. Generally, DBIs are 2-3 mm in size and more commonly found in the mandible in the molar and premolar region. This article further discusses the impact of DBIs on orthodontic treatment such as difficulty with achieving space closure and adequate root tip or torque. We also examine the potential medical implications of DBIs. This is clinically important, especially if multiple DBIs, or osteomas which have a similar radiographic appearance to DBIs, are found in a patient as they may be associated with adenomatous intestinal polyps, which, if not treated, have a 100% chance of becoming malignant transformation.
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  • 文章类型: Journal Article
    OBJECTIVE: The objective of our study was to assess whether the maximum and mean CT attenuations are accurate for differentiating between enostoses and treated sclerotic metastases.
    METHODS: We retrospectively reviewed CT studies of 165 patients (167 lesions) that included 49 patients with 49 benign lesions, 69 patients with 71 sclerotic treated lesions, and 47 patients with 47 untreated lesions, and calculated the mean and maximum CT attenuations of each lesion. ROC curves were used to identify thresholds for differentiating enostoses from treated sclerotic metastases and from untreated sclerotic metastases.
    RESULTS: The maximum CT attenuation of enostoses (1212.0 HU) was higher from that of untreated (754.7 HU) (p = 9.7 × 10-16) and that of treated (891.7 HU) (p = 9.9 × 10-10) sclerotic metastases. The maximum CT attenuation of treated sclerotic metastases (891.7 HU) was higher than that of untreated sclerotic metastases (754.7 HU) (p = 0.003). Enostoses had higher mean CT attenuation (1123.0 HU) than untreated (602.0 HU) (p < 2.2 × 10-16) and treated (731.7 HU) (p = 9.6 × 10-15) sclerotic metastases. A threshold mean CT attenuation of 885 HU had an accuracy of 91.7% and 81.7% to differentiate enostoses from untreated and treated metastases, respectively, whereas a threshold maximum CT attenuation of 1060.0 HU had an accuracy of 81.3% and 72.5% to differentiate enostoses from untreated and treated metastases.
    CONCLUSIONS: The mean and maximum CT attenuations can differentiate between enostoses and sclerotic metastases; however, the accuracy of both metrics decreases after treatment.
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  • 文章类型: Journal Article
    目的:这项研究的目的是确定CT衰减阈值是否可用于区分未经治疗的成骨细胞转移和成骨结瘤。
    方法:研究组包括62例患者,在CT上发现279例硬化骨病变(37例患者中有126例结骨,25例患者中有153例转移)。通过组织学或临床和影像学随访评估硬化性病变的原因。没有患者接受过转移的预先治疗。以Hounsfield单位测量平均和最大衰减。进行ROC分析以确定灵敏度,特异性,AUC,95%CIs,和CT衰减的截止值,以区分转移瘤和结瘤瘤。使用具有95%CI的组内相关系数评估互读再现性。
    结果:烯酮的平均和最大CT衰减值分别为1190±239HU和1323±234HU,分别,骨转移瘤为654±176HU和787±194HU,分别。使用885HU的截止值作为平均衰减,AUC为0.982,灵敏度为95%,特异性为96%。使用1060HU的截止值作为最大CT衰减,AUC为0.976,灵敏度为95%,特异性为96%。烯酮的平均衰减组内相关系数为0.987,转移为0.81。烯酮的最大衰减组内相关系数为0.814,转移灶的最大衰减组内相关系数为0.980。
    结论:CT衰减测量可用于区分未治疗的成骨细胞转移和成骨结瘤。885HU的平均衰减和1060HU的最大衰减提供了可靠的阈值,在该阈值以下,转移性病变是有利的诊断。
    OBJECTIVE: The purpose of this study was to determine whether CT attenuation thresholds can be used to distinguish untreated osteoblastic metastases from enostoses.
    METHODS: The study group comprised 62 patients with 279 sclerotic bone lesions found at CT (126 enostoses in 37 patients and 153 metastases in 25 patients). The cause of sclerotic lesions was assessed histologically or by clinical and imaging follow-up. None of the patients had undergone prior treatment for the metastases. The mean and maximum attenuation were measured in Hounsfield units. ROC analysis was performed to determine sensitivity, specificity, AUC, 95% CIs, and cutoff values of CT attenuation to differentiate metastases from enostoses. Interreader reproducibility was assessed using an intraclass correlation coefficient with 95% CI.
    RESULTS: The mean and maximum CT attenuation values of enostoses were 1190 ± 239 HU and 1323 ± 234 HU, respectively, and those of osteoblastic metastases were 654 ± 176 HU and 787 ± 194 HU, respectively. Using a cutoff of 885 HU for mean attenuation, the AUC was 0.982, sensitivity was 95%, and specificity was 96%. Using a cutoff of 1060 HU for maximum CT attenuation, the AUC was 0.976, sensitivity was 95%, and specificity was 96%. The mean attenuation intraclass correlation coefficient was 0.987 for enostoses and 0.81 for metastases. The maximum attenuation intraclass correlation coefficient was 0.814 for enostoses and 0.980 for metastases.
    CONCLUSIONS: CT attenuation measurements can be used to distinguish untreated osteoblastic metastases from enostoses. A mean attenuation of 885 HU and a maximum attenuation of 1060 HU provide reliable thresholds below which a metastatic lesion is the favored diagnosis.
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  • 文章类型: Case Reports
    一名29岁的男性患者报告更换缺失的牙齿。该患者有右下后牙未萌出的病史,正像图显示下颌第二磨牙向下颌骨下缘的迁移,正好在第二前磨牙的根尖下方,并伴随着内生症向下颌骨的远端,尺寸约为21毫米×20毫米。这种罕见的骨间缺损在决定缺失牙齿的修复治疗方案中起着至关重要的作用,在此类手术期间应格外小心以保护患者的健康。
    A 29-year-old male patient reported for replacement of missing teeth. The patient gave history of unerupted right lower posterior teeth and the orthopantomogram revealed transmigrated mandibular second molar to the inferior border of mandible just below the root apices of second premolar associated with enostosis distally toward the ramus of mandible with size of about 21 mm Χ 20 mm. This rare interosseous defect plays a vital role in deciding prosthetic treatment options for missing teeth and utmost care should be taken to preserve the health of the patient during such procedures.
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  • DOI:
    文章类型: Case Reports
    “致密骨岛”(DBI)是一种不透射线的病变,在Leterature中被称为特发性骨硬化,enostosis,局灶性骨硬化,根尖骨症,和骨疤。DBI是在骨骼结构的常规X射线中偶然发现的。在上颌骨中,通常位于下颌骨,特别是在磨牙区,报告的发病率为2.3%至9.7%。DBI似乎直到青春期的第一阶段才发展,通常在青少年和年轻人中发现。在40%的病例中,经过10年的随访,DBI的规模似乎增加,因为在颌骨和长骨中发现的DBI似乎与骨骼生长成比例增加。介绍了一例26岁的患者,并进行了手术治疗。这是第一例报道的病例,完整的X射线直视摄影随访显示病变自发作以来的演变。
    The \"Dense Bone Island\" (DBI) is a radiopaque lesion referred in leterature as idiopathic osteosclerosis, enostosis, focal osteosclerosis, periapical osteopetrosis, and bone scar. The DBI are accidentally found in routinary Xray of bone structures. In the maxillary bones, often localized in the mandible, especially in the molar region, with a reported incidence ranging from 2.3 to 9.7%. DBI does not seem to develop until the first phase of adolescence and it is usually found in adolescents and in young adults. In 40% of cases DBI seems to increase in size after a 10 year follow-up, because the DBI found in jaws and in long bones seem to increase proportionally to the bone growth. A case of a 26 years old patient and the surgical treatment is presented. This is the first reported case where complete X-ray Orthopantomography follow-up showed the evolution of the lesion since its onset.
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