关键词: CT attenuation bone island enostosis osteoid osteoma osteopoikilosis

Mesh : Adult Bone Diseases Bone Neoplasms / diagnostic imaging Humans Retrospective Studies Tomography, X-Ray Computed

来  源:   DOI:10.3390/medicina56100534   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Bone islands (BI; enostoses) may be solitary or occur in the setting of osteopoikilosis (multiple bone islands) and are sometimes associated with Gardner\'s Syndrome (osteopoikilosis and colonic polyposis). Characteristic features of bone islands are (1) absence of pain or local tenderness, (2) typical radio dense central appearance with peripheral radiating spicules (rose thorn), (3) Mean CT (computerized tomography) attenuation values above 885 Hounsfield units (HU) (4) absence of uptake on bone scan and (5) radiographic stability over time. However, when enostoses display atypical features of pain, unusual radiographic appearance, aberrant HU, increased radiotracer uptake, and/or enlargement, they can be difficult to differentiate from more sinister bony lesions such as osteoblastic metastasis, low grade central osteosarcoma, osteoid osteoma and osteoblastoma. In this retrospective case series, the demographic, clinical, radiographic, treatment and outcome for ten patients with eleven atypical bone islands (ABI) are presented, some showing associated pain (5), some with atypical radiographic appearance (3), some with increased activity on BS (4), some with documented enlargement over time (7), one with abnormal CT attenuation value, some in the setting of osteopoikilosis (2), one in the setting of Gardner\'s Syndrome and one osteoid osteoma simulating a bone island. This series represents the spectrum of presentations of ABI. Comprehensive review of the literature reveals that the previous largest series of ABI showing enlargement as the atypical feature was in younger patients with jaw BI. Hence, this represents one of the largest series reported of ABI of all types in adults.
摘要:
骨岛(BI;烯酮)可能是孤立的或发生在骨质疏松(多个骨岛)的背景下,有时与Gardner综合征(骨质疏松和结肠息肉病)相关。骨岛的特征是(1)没有疼痛或局部压痛,(2)典型的无线电密集的中心外观,外围辐射针状(玫瑰刺),(3)平均CT(计算机断层扫描)衰减值高于885Hounsfield单位(HU)(4)在骨扫描中没有摄取和(5)随时间的射线照相稳定性。然而,当结骨显示出非典型的疼痛特征时,不寻常的射线照相外观,异常的HU,增加的放射性示踪剂摄取,和/或扩大,它们可能很难与更险恶的骨性病变区分开来,如成骨细胞转移,低级中央骨肉瘤,骨样骨瘤和骨母细胞瘤。在这个回顾性案例系列中,人口统计,临床,射线照相,介绍了10例具有11个非典型骨岛(ABI)的患者的治疗和结果,一些显示相关的疼痛(5),有些具有非典型的射线照相外观(3),一些在BS上的活性增加(4),一些随着时间的推移有记录的扩大(7),一个异常的CT衰减值,一些在骨质疏松的背景下(2),一个在加德纳综合症的背景下,一个模拟骨岛的骨样骨瘤。这个系列代表了ABI的表现谱。对文献的综合回顾表明,先前最大的ABI系列表现为非典型特征的增大是在较年轻的下颌BI患者中。因此,这是成人所有类型ABI报告的最大系列之一.
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