en bloc excision

整体切除
  • 文章类型: Case Reports
    动脉瘤样骨囊肿是良性的,最常见的非肿瘤性病变影响骨。在某些情况下报告了恶性转化,虽然罕见。它通常发生在年轻人中,大约75%的病例发生在前二十年,95%发生在前三十年。管理取决于个体病例参数,ABC发生在骨骼的负重区域,保证积极的治疗计划,同时考虑预防病理性骨折。
    一名20岁男性患者,没有其他合并症,向我们介绍了9个月的非创伤性右髋部疼痛。在X射线的初步临床检查和影像学研究中,CT扫描,MRI,患者被诊断为右股骨近端动脉瘤样骨囊肿(ABC)。该患者接受了病灶内切除术,并进行了长期刮治和DHS钢板预防性固定,并每年进行一次随访。10年的随访显示病变完全消退,然后进行植入物移除。
    从这种情况可以清楚地看出,动脉瘤样骨囊肿的治疗需要根据患者的年龄进行个体化,投诉,和肿瘤的侵袭性,尺寸,和它的程度。通常,需要进行全面刮除的整块切除以及植骨和预防性固定,以支持植骨并防止病理性骨折和进一步复发。如果需要,应在病变完全消退后进行植入物切除,患者意愿,和任何其他医学适应症。
    UNASSIGNED: Aneurysmal bone cyst is a benign, most often non-neoplastic lesion affecting the bone. Malignant transformation is reported in certain cases, although rare. It commonly occurs in young adults with around 75% of the cases occurring in the first two decades and 95% occurring in the first 3 decades. The management depends on the individual case parameters with ABC occurring in a weight-bearing area of a bone warranting an aggressive treatment plan with the consideration of preventing a pathological fracture.
    UNASSIGNED: A 20-year-old male patient with no other comorbidities presented to us with complaints of atraumatic right hip pain of 9-month duration. On preliminary clinical examination and imaging studies with X-rays, CT scan, and MRI, the patient was diagnosed to have an aneurysmal bone cyst (ABC) of the right proximal femur. The patient was operated with intra-lesional excision with extended curettage and prophylactic fixation with DHS plating and kept on yearly follow-up. 10-year follow-up showed complete resolution of the lesion and implant removal was done after that.
    UNASSIGNED: As is clear from this case, the treatment of an aneurysmal bone cyst needs to individualized based on the patient\'s age, complaints, and tumor behavior in terms of its aggressiveness, size, and its extent. Often, en bloc excision with extensive curettage is required along with bone grafting and prophylactic fixation to support the bone graft and to prevent a pathological fracture and further recurrence. Implant removal if indicated should be done after complete resolution of the lesion, patient willingness, and any other medical indication.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    表现为脊髓病变症状的椎体骨软骨瘤是非常罕见的脊柱骨软骨瘤实体,其起源于椎体的后表面并导致椎管狭窄和脊髓压迫。在这种情况下,早期明确的诊断和随后的成功治疗是必要的,以防止危及生命的并发症。
    在这种情况下,我们报告一例20岁女性出现机械性颈部疼痛,步态不稳定,在过去的3个月里,头晕与神经功能缺损。颈椎的MRI显示肿块从C6椎体的后部生长并向椎管延伸,导致明显的脊髓压迫.
    以下病例报告不仅描述了椎体骨软骨瘤的罕见表现,而且还强调了通过整块切除肿瘤和颈椎前路融合的手术治疗,结果良好,无任何复发。
    UNASSIGNED: Vertebral body osteochondroma presenting with myelopathic symptoms is exceptionally rare entity of spinal osteochondroma which arises from the posterior surface of vertebral body and leading to spinal canal stenosis and cord compression. Early definitive diagnosis and subsequent successful treatment is necessary in such cases to prevent life threatening complications.
    UNASSIGNED: In this context, we report a case of a 20-years old female presented with mechanical neck pain, unsteady gait, giddiness with neurological deficit for the past 3 months. An MRI of the cervical spine revealed a mass growing from the posterior aspect of the C6 vertebral body and extending toward the vertebral canal, causing marked spinal cord compression.
    UNASSIGNED: The following case report not only describes the rare presentations of vertebral body osteochondroma but also emphasizes on surgical management by en bloc resection of tumor and anterior cervical fusion, resulting in a favorable outcome without any recurrence.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    恶性周围神经鞘瘤(MPNST)是一种罕见的软组织肉瘤,复发率高,预后差。早期诊断和完整的手术切除是治疗的基本原则。良性表现和低临床怀疑通常会延迟明确诊断,根据肿瘤的大小和位置,整块切除可能不可行。我们描述了通过手术切除成功治疗的复发性MPNST的罕见病例。
    一名35岁的女性在前臂未完全切除MPNST3个月后出现了快速增长的疼痛肿块。分期调查显示没有转移的证据。病人接受了整块手术切除,劈裂植皮,和辅助放射治疗。组织学和免疫组织化学分析证实MPNST。手术五年后,患者没有复发的证据,并且功能良好。
    MPNST是罕见的软组织肉瘤,可以伪装成良性肿块。关于手术治疗复发性疾病的结果的文献很少。尽管肿瘤局部复发,完整的手术切除可以产生优异的临床效果。
    UNASSIGNED: A malignant peripheral nerve sheath tumor (MPNST) is a rare soft-tissue sarcoma with a high recurrence rate and poor prognosis. Early diagnosis and complete surgical excision are the fundamental principles of treatment. A benign presentation and low clinical suspicion often delay definitive diagnosis, and en bloc excision may not be feasible depending on the size and location of the tumor. We describe a rare case of a recurrent MPNST successfully treated by surgical excision.
    UNASSIGNED: A 35-year-old woman presented with a rapidly growing painful mass 3 months following incomplete removal of a MPNST from her forearm. Staging investigations showed no evidence of metastasis. The patient underwent en-bloc surgical excision, split skin grafting, and adjuvant radiation therapy. Histology and immunohistochemical analysis confirmed a MPNST. Five years after having surgery, the patient shows no evidence of recurrence and has excellent function.
    UNASSIGNED: MPNST are rare soft tissue sarcomas that can masquerade as benign lumps. There is a paucity of literature on the outcome of surgically-treated recurrent disease. Notwithstanding local recurrence of the tumor, complete surgical excision can yield excellent clinical results.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    骨软骨瘤是最常见的良性骨肿瘤之一。主要涉及长骨的骨端,涉及脊柱的情况很少见。它经常涉及竞争,其次是胸椎和腰椎,很少累及骶骨.我们报告了the骨孤立性骨软骨瘤的影像学发现。患者是一名37岁的女性,临床上表现为进行性腰痛,伴有左臀部疼痛和不适。CT和MRI显示病变起源于S1的左椎板,向前和向上生长,导致L5椎骨的压缩再吸收,左椎间孔狭窄及邻近神经根肿胀。患者接受了手术,肿块被完全切除,术后恢复良好。由骶骨引起的骨软骨瘤很少见,可导致相邻骨的压缩再吸收,和成像技术有利于病灶的定位和表征,为临床治疗提供有用的信息。
    Osteochondroma is one of the most common benign bone tumors, mainly involving the bone ends of long bones, and involving the spine is rare. It often involves the competing, followed by the thoracic and lumbar spine, and rarely involves the sacrum. We report the imaging findings of a solitary osteochondroma of the sacrum. The patient was a 37-year-old woman who presented clinically with progressive low back pain associated with left buttock pain and discomfort. CT and MRI showed that the lesion originated from the left lamina of S1 and grew anteriorly and superiorly, resulting in compressive resorption of the L5 vertebral bone, left foraminal stenosis and adjacent nerve root swelling. The patient underwent surgery and the mass was completely excised and recovered well postoperatively. Osteochondroma arising from the sacrum is rare and can lead to compressive resorption of adjacent bone, and imaging techniques are conducive to the localization and characterization of the lesion and provide useful information for clinical treatment.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    骨软骨瘤是最常见的良性骨肿瘤,其中软骨形成性病变源自软骨周环的异常软骨。虽然它通常来自长骨的生长末端,不太常见,它可能来自肩胛骨,骨盆,或椎骨。
    我们遇到了一位16岁的男性患者,患有3年无痛的左骨盆实性肿块,X线和磁共振成像结果提示骨软骨瘤。除了化妆品问题,手术的主要适应症是穿着裤子/短裤/腰带的持续不适。他接受了整体切除术,然后由两名独立的组织病理学家对手术标本进行活检,确认肿瘤为骨软骨瘤。随访2年,无术后并发症或复发迹象。这个病例是少数报道的影响髂翼的病例之一,切除是在骨骼成熟之前进行的。我们还对目前关于髂翼骨软骨瘤的文献进行了回顾,以更好地了解肿瘤,确定当前知识中的差距,并提出未来研究的领域。
    由于鉴别诊断之一包括继发性软骨肉瘤,这可能是骨软骨瘤的罕见进展,对此类异常病例的早期识别和综合评估需要高度怀疑,以避免误诊并提供有效的治疗。
    UNASSIGNED: Osteochondroma is the most common benign bone tumor where a chondrogenic lesion is derived from aberrant cartilage from the perichondral ring. Although it commonly arises from the growing ends of long bones, less commonly, it may arise from the scapula, pelvis, or vertebra.
    UNASSIGNED: We encountered a 16-year-old male patient with a painless left pelvic solid mass for 3 years, which was suggestive of osteochondroma on X-ray and magnetic resonance imaging findings. Besides cosmetic issues, the main indication for surgery was the constant discomfort in wearing pants/shorts/belts. He underwent en bloc excision followed by a biopsy of the surgical specimen by two independent histopathologists confirming the tumor to be osteochondroma. He was followed up for 2 years with no signs of post-operative complications or recurrence. This case represents one of the very few reported so affecting the iliac wing, where the excision was performed before skeletal maturation. We also performed a review of the current literature on iliac wing osteochondroma to understand the tumor better, identify gaps in current knowledge, and suggest areas for future research.
    UNASSIGNED: Since one of the differential diagnoses includes secondary chondrosarcoma, which could be a rare progression of osteochondroma, early recognition and comprehensive evaluation of such unusual cases needs to be dealt with a high index of suspicion to avoid misdiagnosis and to provide effective treatment.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    背景:去分化脂肪肉瘤(DDLS)的预后较差,最常见于腹膜后区域,很少发生在腹膜内区域。组织免疫化学和分子生物学的共同贡献彻底改变了组织学诊断。除了手术,对于这种化学耐药癌症的最佳治疗方法尚无共识。
    方法:一名30岁的黑人女性出现了一个巨大的腹部疼痛肿块,几乎占据了整个腹部,并接受了手术治疗。腹部计算机断层扫描显示肠系膜有很大的异质性肿块,大小为18cm×16cm,对比度增强不均匀。在剖腹手术中,整块切除大且多小叶的胃结肠韧带肿块。术后最初的组织病理学诊断为未分化肉瘤。最后,免疫组织化学和分子生物学的结果使我们能够确认DDLS的诊断。肿瘤伴随着弥漫性转移的侵袭性发展,导致患者在手术后不到5个月死亡。
    结论:去分化脂肪肉瘤是罕见的肿瘤,通常起源于腹膜后,但可能出现在意外部位。
    BACKGROUND: Dedifferentiated liposarcoma (DDLS) has a worse prognosis and occurs most commonly in the retroperitoneal region and rarely in the intraperitoneal region. Histological diagnosis was revolutionized by the combined contributions of histo-immuno-chemistry and molecular biology. Aside from surgery, there is no consensus on the optimal treatment for this chemoresistant cancer.
    METHODS: A thirty-year-old black female presented with a large painful abdominal mass occupying nearly the entire abdomen and progressive weight loss was admitted for surgery. Abdominal computed tomography showed a large heterogeneous mass of the mesentery that was sized 18 cm × 16 cm in size and had heterogeneous contrast enhancement. During laparotomy, en bloc excision of the large and multilobulated gastrocolic ligament mass was performed. The initial postoperative histopathological diagnosis was undifferentiated sarcoma. Finally, the results of immunohistochemistry and molecular biology allowed us to confirm the diagnosis of DDLS. The tumour followed an aggressive evolution with diffuse metastasis, causing the death of the patient less than 5 mo after the operation.
    CONCLUSIONS: Dedifferentiated liposarcomas are rare tumours that typically originate in the retroperitoneum but may arise in unexpected locations.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Video-Audio Media
    血管母细胞瘤是良性的,WHO1级肿瘤相对罕见。[1]它们可能是散发性的或与vonHippel-Lindau病(VHL)有关。后颅窝血管母细胞瘤出现在小脑半球,在其他网站不太常见,如髓样血管母细胞瘤。[2-4]它们的特征性放射学特征,包括囊实性形态和突出血管有助于术前诊断。[5]在这个手术视频中,我们讨论了在对大型髓样血管母细胞瘤进行手术时避免并发症的技术细微差别和步骤。一位19岁的女士出现头痛,呕吐和视力恶化2个月的持续时间。在检查中,她的右侧视力为4/60,6/60左侧,双侧乳头水肿,躯干和步态共济失调。由于她出现在感觉改变和CT头部显示脑积水,在紧急情况下进行了脑室-腹腔分流术.进行了适当的放射学检查。根据放射学发现,她被暂时诊断为血管母细胞瘤,并计划进行手术。术前血管造影显示肿瘤有强烈的腮红,但栓塞被认为是不可行的,因为肿瘤有多个供血血管。分流手术后五天进行了明确的肿瘤切除手术。患者家属同意手术,并使用图像和临床数据发表。手术视频突出了肿瘤的位置,其突出的血液供应和静脉引流,术中神经监测的使用,以及整体切除的技术细微差别。患者术后即刻出现左外侧凝视(第6神经)麻痹,在接下来的三个月里解决了。术后及随访影像学证实肿瘤完整切除。现代显微外科技术和对肿瘤脉管系统的透彻了解有助于对此类肿瘤进行安全和完整的切除。[1-2]整块切除仍然是血管母细胞瘤手术的主要方法。
    Hemangioblastomas are benign World Health Organization grade 1 tumors that are relatively rare.1 They may be sporadic or found in association with von Hippel-Lindau disease. Posterior fossa hemangioblastomas arise in the cerebellar hemisphere and, less commonly, at other sites such as medullary hemangioblastomas.2-4 Their characteristic radiologic features including solid-cystic morphology and prominent vessels aid in the preoperative diagnosis.5 In this operative video, we discuss the technical nuances and steps to avoid complications while operating on a large medullary hemangioblastoma. A 19-year-old lady presented with headache, vomiting, and visual deterioration of 2 months\' duration. On examination, she had visual acuity of 4/60 right side, 6/60 left side, bilateral papilledema, and truncal and gait ataxia. Since she had presented in altered sensorium and a computed tomography head scan showed hydrocephalus, a ventriculoperitoneal shunt was placed on an emergency basis. Proper radiologic workup was done. On the basis of radiologic findings, she was provisionally diagnosed to have hemangioblastoma and surgery was planned. Preoperative angiogram showed an intense tumoral blush, but embolization was deemed infeasible since the tumor had multiple feeding vessels. Definitive surgery for tumor excision was performed 5 days after the shunt surgery. The patient\'s family consented to the procedure and the use of images and clinical data for publication. Video 1 highlights the tumor location, its prominent blood supply and venous drainage, use of intraoperative neuromonitoring, and the technical nuances for an en bloc excision. The patient had a left lateral gaze (sixth nerve) palsy in the immediate postoperative period, which resolved over the next 3 months. Postoperative and follow-up imaging confirmed complete tumor excision. Modern microsurgical techniques and a thorough understanding of the tumor vasculature help in performing safe and complete excision of such tumors.1,2 En bloc excision remains the mainstay of surgery for hemangioblastomas.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    动静脉畸形(AVM)是发育性血管畸形,由中央眼窝周围的异常动静脉分流组成。这些病变相对不常见,仅占所有良性软组织肿块的7%。大多数AVM发生在大脑中,脖子,骨盆,和下肢,很少出现在脚上。当它们在脚上形成时,非特异性疼痛和缺乏临床特征导致初次就诊时误诊率高。尽管手术切除联合栓塞治疗已成为大型AVM的首选治疗方法,关于足部小病变的最佳治疗方法存在争议。
    一名36岁的非洲裔加勒比男子被转诊到诊所,有2年的前脚疼痛加剧,影响他舒适站立或行走的能力。没有外伤史,尽管换了鞋,患者继续有明显的疼痛。临床检查不明显,除了前脚背部有轻度压痛,X光片正常.磁共振扫描报告了meta骨间血管肿块,但不能排除恶性肿瘤。手术探查和整体切除证实肿块为AVM。手术后一年,患者保持无痛状态,无复发迹象.
    AVM在脚下的稀有性,结合正常的X线片和非特异性临床体征,导致这些病变的诊断和治疗延误。在诊断不确定的情况下,外科医生获得磁共振成像的阈值应该很低。整块手术切除是治疗足部小的适当位置病变的一种选择。
    UNASSIGNED: Arteriovenous malformations (AVM) are developmental vascular malformations consisting of abnormal arteriovenous shunts surrounding a central nidus. These lesions are relatively uncommon, comprising just 7% of all benign soft-tissue masses. Most AVMs occur in the brain, neck, pelvis, and lower extremity and rarely manifest in the foot. When they do form in the foot, non-specific pain and the absence of clinical features contribute to the high rate of misdiagnosis on initial presentation. Although surgical excision combined with embolotherapy has emerged as the preferred treatment for large AVM, controversy exists over the best treatment for small lesions in the foot.
    UNASSIGNED: A 36-year-old Afro-Caribbean man was referred to the clinic with a 2-year history of increasing pain in his forefoot, affecting his ability to stand or walk comfortably. There was no history of trauma, and despite changing his footwear, the patient continued to have significant pain. Clinical examination was unremarkable except for mild tenderness over the dorsum of his forefoot, and radiographs were normal. A magnetic resonance scan reported an intermetatarsal vascular mass but could not exclude malignancy. Surgical exploration and en bloc excision confirmed the mass to be an AVM. One year post-surgery, the patient remains pain-free with no evidence of recurrence.
    UNASSIGNED: The rarity of AVM in the foot, combined with normal radiographs and non-specific clinical signs, contributes to the long delay in diagnosing and treating these lesions. Surgeons should have a low threshold for obtaining magnetic resonance imaging in cases of diagnostic uncertainty. En bloc surgical excision is an option for treating small suitably located lesions in the foot.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    巨大的颈性甲状腺肿,定义为直径大于8厘米的甲状腺肿块,通常是结节性或腺瘤性甲状腺肿。巨大的颈性甲状腺肿也可能是由甲状腺功能亢进引起的(即,桥本甲状腺炎)。桥本病患者的手术指征包括疑似恶性肿瘤,与疾病相关的持续症状,或甲状腺肿的持续扩大。我们在此描述了一名从甲状腺肿瘤中出现压迫症状的女性,其数量几乎是迄今为止相关文献报道的最大数量。通过完全整块切除切除巨大甲状腺肿瘤的双侧叶。我们保护了双侧喉返神经,并保留了双侧上,下甲状旁腺原位。切除左叶肿瘤16×9×5.5cm,而右叶肿瘤为12×8×4厘米。病理诊断为桥本甲状腺炎。虽然手术切除很困难,目前仍是桥本氏甲状腺炎患者巨大甲状腺肿的主要治疗方式,有助于减少并发症的发生。
    A giant cervical goiter, defined as a thyroid mass larger than 8 cm in diameter, is usually a nodular or adenomatous goiter. A giant cervical goiter can also be caused by hyperthyroidism (i.e., Hashimoto\'s thyroiditis). The surgical indications for patients with Hashimoto\'s disease include suspected malignant tumors, persistent symptoms related to the disease, or persistent enlargement of the goiter. We herein describe a woman who developed symptoms of compression from a thyroid tumor, the volume of which was almost the largest reported in the relevant literature to date. The bilateral lobes of the giant thyroid tumor were removed by total en bloc excision. We protected the bilateral recurrent laryngeal nerve and preserved the bilateral upper and lower parathyroid glands in situ. The excised left lobe tumor was 16 × 9 × 5.5 cm, whereas the right lobe tumor was 12 × 8 × 4 cm. The pathological diagnosis was Hashimoto\'s thyroiditis. Although surgical excision is difficult, it is still the main treatment modality for giant goiters in patients with Hashimoto\'s thyroiditis and can help to reduce the occurrence of complications.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    未经证实:上尿路尿路上皮癌(UTUC)是一种高度系统性侵袭性疾病,具有快速淋巴结浸润和转移的趋势,肿瘤预后较差。肿瘤的输尿管定位导致肾积水和早期侵入肌壁,被归类为高危肿瘤。
    方法:一名70岁女性被诊断为左输尿管下段尿路上皮肿瘤,伴有肾积水和主动脉旁和髂旁淋巴结肿大。该疾病被分层为高风险的上尿路尿路上皮癌。治疗包括根治性肾输尿管切除术,使用机器人和3D腹腔镜联合方法进行膀胱袖状切除术和宽淋巴结清扫。
    UNASSIGNED:使用微创方法可以提供精确的解剖和组织操作以及快速的术后恢复和早期辅助肿瘤治疗,从而克服了手术挑战。全面完整的淋巴结清扫术以及精确的膀胱袖套切除可改善分期,可能影响疾病预后。
    结论:整体微创肾癌根治术,膀胱袖状切除术和宽淋巴结清扫术提供了改进的手术时间和淋巴结清扫术,更好地管理输尿管远端和膀胱袖状切除术,水密性膀胱手术和最佳疾病分期。在这种情况下,主要外科医生使用3D腹腔镜检查的经验来优化手术肾脏步骤的手术时间。达芬奇机器人的轻柔而精确的运动允许精确的整体解剖(pN2,N4/15),这对分期以及可能的肿瘤学结果都有影响。
    UNASSIGNED: Upper tract urothelial carcinoma (UTUC) is a highly systemic aggressive disease with a tendency of rapid lymph node invasion and metastasis presenting poor oncologic outcomes. Ureteral localization of tumors leads to hydronephrosis and early invasion of the muscle wall, being categorized as high risk tumors.
    METHODS: A 70 years old female was diagnosed with lower left ureteral urothelial tumor associated with hydronephrosis and paraaortic and iliac enlarged lymph nodes. The disease was stratified as high risk upper tract urothelial carcinoma. Treatment consisted in en bloc radical nephroureterectomy, bladder cuff excision and wide lymph node dissection using a combined robotic and 3D laparoscopic approach.
    UNASSIGNED: Surgical challenges are surpassed by the use of minimal invasive approaches that offer precise dissection and tissue manipulation with a fast postoperative recovery and early adjuvant oncologic treatment. Comprehensive and complete lymph node dissection along with precise bladder cuff excision offers improved staging, possibly impacting disease prognosis.
    CONCLUSIONS: En bloc minimal invasive radical nephroureterectomy, bladder cuff excision and wide lymph node dissection offer improved surgery time and lymph node dissection, better management of distal ureteral and bladder cuff excision, watertight cystorrhaphy and optimal disease staging. The experience of the main surgeon with 3D laparoscopy was used in the hereby case to optimize operatory time for the renal step of the surgery. The gentle and precise movements of the Da Vinci robot allowed an accurate en bloc dissection (pN2, N4+/15) with implications in staging and possibly also in oncologic outcomes.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号