在过去的30年中,消化系统疾病的全球负担一直在上升。发病率和趋势,死亡,需要调查消化系统疾病的残疾调整寿命年(DALYs)。
■我们从全球疾病负担2019网站提取了1990-2019年之间的总体消化系统疾病和病因数据,包括绝对数量和相应的年龄标准化发病率(ASIR),死亡(ASDR),和DALYs(ASDALYs)。
■全球,事件案例,死亡,和2019年消化系统疾病DALYs分别增长74.44、37.85和23.46%,分别,与1990年相比,ASIR增加了0.09%,以及每年减少1.38%和1.32%的ASDR和ASDALYs。总体消化系统疾病的社会人口统计学指数(SDI)显示ASIR从低到中低地区略有增加。在所有SDI地区都发现了ASDR和ASDALYs的下降趋势。女性发病率较高,而男性的总体消化系统疾病和大多数原因的死亡和DALYs负担较高。估计的年度百分比变化与基线ASIR显著相关,ASDR,以及整个消化系统疾病的ASDALYS,和ASDR之间的负相关,ASDALYs,1990年(R=-0.68,R=-0.69)和2019年(R=-0.71,R=-0.73)的人类发展指数均被注意到。
■研究结果表明,消化系统疾病仍然是重大的公共卫生负担,各国差异很大,性别,和年龄组。因此,执行年龄,性别,以及针对特定国家的早期筛查政策和有针对性的干预措施可以显着减轻消化系统疾病的全球负担。
The global burden of digestive diseases has been rising in the last 30 years. The rates and trends of incidence, deaths, and disability-adjusted life-years (DALYs) for digestive diseases need to be investigated.
We extracted the data on overall digestive diseases and by cause between 1990-2019 from the Global Burden of Diseases 2019 website, including the absolute number and the corresponding age-standardized rates of incidence (ASIR), deaths (ASDR), and DALYs (ASDALYs).
Globally, the incident cases, deaths, and DALYs of digestive diseases in 2019 increased by 74.44, 37.85, and 23.46%, respectively, compared with that in 1990, with an increasing ASIR of 0.09%, as well as decreasing ASDR and ASDALYs of 1.38 and 1.32% annually. The sociodemographic index (SDI) of overall digestive diseases showed a slight increase in ASIR from low to middle-low regions. The downtrend in ASDR and ASDALYs was found in all SDI regions. The burden of incidence was higher in females, while the burden of deaths and DALYs was higher in males for the overall digestive diseases and most causes. The estimated annual percentage changes were significantly associated with the baseline ASIR, ASDR, and ASDALYs for the overall digestive diseases, and the negative correlations between ASDR, ASDALYs, and human development index both in 1990 (R = -0.68, R = -0.69) and 2019 (R = -0.71, R = -0.73) were noticed.
The findings indicate that digestive diseases remain a significant public health burden, with substantial variation across countries, sexes, and age groups. Therefore, implementing age, gender, and country-specific policies for early screening and targeted interventions could significantly reduce the global burden of digestive diseases.