developmental cyst

发育性囊肿
  • 文章类型: Journal Article
    背景:由于潜在的感染或恶性肿瘤,建议完全切除骶前表皮样囊肿。经骶及经腹入路已用于治疗骶前肿瘤。然而,没有标准的手术切除方法。我们介绍了一名接受腹腔镜经腹切除术的肥胖男性患者的s前表皮样囊肿。
    方法:一名44岁男子被转诊到我院治疗盆底囊性肿瘤。对比增强计算机断层扫描显示直肠左腹侧有一个45×40-mm的肿瘤,坐骨脊柱的右侧,精囊的背侧,在第五骶骨的前面.增强的磁共振成像显示多房囊性肿瘤,在T2加权图像上具有高和低的信号强度。肿瘤被诊断为表皮样囊肿。我们考虑了经骶骨或腹腔镜入路,并决定进行腹腔镜辅助经腹切除术,因为肿瘤位于远离骶骨的前方,由于臀部厚度的可见度差,经骶骨入路会导致更大的疤痕。整个肿瘤在腹腔镜引导下安全切除,因为腹腔镜经腹入路即使在狭窄的盆腔和小的皮肤切口中也能提供良好的放大视野,可以安全切除盆腔器官,船只,和神经,同时观察肿瘤轮廓。
    结论:腹腔镜经腹手术是治疗肥胖患者骶前肿瘤的有效方法。
    BACKGROUND: Complete resection of presacral epidermoid cysts is recommended due to the potential for infection or malignancy. Transsacral and transabdominal approaches have been used to treat presacral tumors. However, there are no standard surgical approaches to resection. We present the case of a presacral epidermoid cyst in an obese male patient who underwent laparoscopic transabdominal resection.
    METHODS: A 44-year-old man was referred to our hospital for treatment of a cystic tumor on the pelvic floor. Contrast-enhanced computed tomography revealed a 45 × 40-mm tumor on the left ventral side of the rectum, right side of the ischial spine, dorsal side of the seminal vesicles, and in front of the 5th sacrum. Enhanced magnetic resonance imaging revealed a multilocular cystic tumor with high and low signal intensities on T2-weighted images. The tumor was diagnosed as an epidermoid cyst. We considered the transsacral or laparoscopic approach and decided to perform a laparoscopic-assisted transabdominal resection since the tumor was in front of away from the sacrum, and a transsacral approach would result in a larger scar due to poor visibility from the thickness of the buttocks. The entire tumor was safely resected under laparoscopic guidance, because the laparoscopic transabdominal approach can provide a good and magnified field of view even in a narrow pelvic cavity with small skin incisions, allowing safe resection of the pelvic organs, vessels, and nerves while observing the tumor contour.
    CONCLUSIONS: The laparoscopic transabdominal approach is an effective method for treating presacral tumors in obese patients.
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  • 文章类型: Review
    背景:用牙源性角化囊肿重建整个牙列是一个非常具有挑战性的难题。据报道,大多数牙源性角化囊肿是良性的,导致上颌和下颌牙列严重咬合差异。牙科X光片偶尔会显示一种罕见的,局部侵袭性发展中的囊肿称为牙源性角化囊肿,通常位于后颌。当这种囊肿发生在前部区域时,由于对牙髓活力测试缺乏反应,常被误诊为其他根尖周病变。
    方法:本临床病例描述了一名诊断为牙源性角化囊肿患者的牙髓治疗。一名37岁的印度男性患者向该部门报告,左下后牙的搏动性疼痛需要进行牙髓治疗。该患者还出现了颌骨前部区域的牙源性角化囊肿,为此他接受了手术康复。此病例报告重点介绍了诊断为牙源性角化囊肿的患者的牙髓治疗的临床方案。随访期后未发现咀嚼损伤,治疗结果成功。
    结论:本病例报告详细介绍了特征性射线照相发现,和牙源性角化囊肿极为罕见的患者的牙髓治疗。管理涉及康复的多学科方法。
    BACKGROUND: Reconstruction of the entire dentition with odontogenic keratocyst is a very challenging quandary. Most cases of odontogenic keratocyst are often reported to be benign, resulting in severe occlusal discrepancies with the maxillary and mandibular dentition. Dental radiographs occasionally reveal an uncommon, locally aggressive developing cyst termed as odontogenic keratocyst, which is typically located in the posterior jaw. When this cyst occurs in the anterior region, it is often misdiagnosed with other periapical lesions due to its lack of response to pulp vitality tests.
    METHODS: This clinical case scenario demarcates the endodontic management of a patient diagnosed with odontogenic keratocyst. A 37-year-old Indian male patient reported to the department with throbbing pain in the lower left posterior tooth requiring endodontic therapy. This patient also presented with odontogenic keratocyst in the anterior region of the jaw, for which he had undergone surgical rehabilitation. This case report highlights the clinical protocol for the endodontic therapy in patient diagnosed with ododntogenic keratocyst. Masticatory impairment was not visible after the follow-up period and the treatment outcome was successful.
    CONCLUSIONS: This case report details the presentation, characteristic radiographic findings, and endodontic management of a patient with an extremely rare condition of odontogenic keratocyst. The management involves multidisciplinary approach for the rehabilitation.
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  • 文章类型: Case Reports
    Dentigerous cysts are a common cystic pathology that develop between the first and third decade of life and are mainly associated with impacted or erupted mandibular third molars followed by maxillary canines and maxillary third molars. These kinds of cysts are the result of the proliferation of enamel epithelium after its formation, the pathogenesis of which is not clear. Few of these cysts have been reported in pediatric patients. The following case report presents the rare occurrence of a dentigerous cyst in a 6-year-old boy and describes the treatment administered.
    Los quistes dentígeros son una patología quística común que se desarrolla entre la primera y la tercera década de la vida, y se asocian principalmente con terceros molares mandibulares incluidos o erupcionados, seguidos de caninos superiores y terceros molares superiores. Este tipo de quistes son el resultado de la proliferación del epitelio del esmalte después de su formación, cuya patogenia no está clara. Se han informado pocos de estos quistes en pacientes pediátricos. El siguiente reporte de caso presenta la rara ocurrencia de un quiste dentígero en un niño de 6 años y describe el tratamiento administrado.
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  • 文章类型: Journal Article
    直肠后间隙的囊肿包括一组异质的罕见病变。大多数从胚胎遗留物发展,包括尾肠囊肿,皮样囊肿,直肠重复囊肿,肛管重复囊肿,骶尾部畸胎瘤和前脑膜囊肿。尾肠囊肿是最常见的发育起源囊肿,通常表现为多房性囊性肿块,有粘液样内容物,由多种上皮类型排列。与尾肠囊肿相比,直肠重复囊肿显示大肠壁的所有层,包括明确的固有肌层。非发育起源的直肠后囊肿很少见,代表的病变很少涉及直肠后间隙或经历广泛的囊性改变。这篇综述概述了直肠后间隙囊性病变的各种组织学类型,分为发育起源的囊肿和非发育起源的囊肿。提出了一种实用的病理学和多学科方法来诊断这些病变。
    Cysts of the retrorectal space comprise a heterogeneous group of rare lesions. Most develop from embryological remnants and include tailgut cysts, dermoid cysts, rectal duplication cysts, anal canal duplication cysts, sacrococcygeal teratomas and anterior meningocoele. Tailgut cyst is the most common cyst of developmental origin, usually presenting as a multilocular cystic mass with mucoid content and lined by multiple epithelial types. Compared with tailgut cysts, rectal duplication cysts display all layers of the large bowel wall including a well-defined muscularis propria. Retrorectal cysts of non-developmental origin are far less common and represent lesions that either infrequently involve the retrorectal space or undergo extensive cystic change. This review provides an overview of the various histological types of cystic lesions of the retrorectal space, divided into cysts of developmental origin and those of non-developmental origin. A practical pathological and multidisciplinary approach to diagnosing these lesions is presented.
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  • 文章类型: Case Reports
    背景:脊髓支气管囊肿是由胚胎发育错误引起的罕见实体,由呼吸道上皮细胞组成。迄今为止,还有其他三个关于髓内囊肿的报道,部分切除,因此需要密切随访和监测。作者介绍了一例患者出现Klippel-Feil异常和上颈椎大的髓内支气管囊肿的情况。
    方法:作者在进行C2-6椎板切除术时注意到C5-6椎板的融合。硬脑膜开放后,髓内病变有光滑,立即观察到从脊髓背侧出现的纤维成分。脊髓背侧未受累于该囊肿壁或其他较小的囊肿,都含有灰色液体。囊肿壁部分切除,送病理检查。
    结论:脊柱发育性囊肿与其他解剖异常有关,比如Klippel-Feil异常,胚胎发育中的错误引起的。对于髓内病变,例如该患者的支气管囊肿,部分切除和减压是手术的目标,因为积极的减积可能导致神经系统受损。密切成像随访是必要的。
    BACKGROUND: Spinal bronchogenic cysts are rare entities arising from errors in embryogenesis and consisting of respiratory epithelial cells. To date, there are three other published accounts of intramedullary cysts, which were partially resected and thereby warrant close follow-up and monitoring. The authors present an illustrative case of a patient presenting with Klippel-Feil anomaly and a large intramedullary bronchogenic cyst in the upper cervical spine.
    METHODS: The authors noted fusion of the C5-6 laminae as they performed the C2-6 laminectomy. After dural opening, an intramedullary lesion with a smooth, fibrous component emerging from the dorsal spinal cord was immediately observed. The dorsal spinal columns were not involved with this cyst wall or the other smaller cysts, which all contained gray fluid. The cyst walls were partially resected and sent for pathological examination.
    CONCLUSIONS: Spinal developmental cysts are associated with other anatomical anomalies, such as Klippel-Feil anomaly, arising from errors in embryogenesis. For intramedullary lesions such as this patient\'s bronchogenic cyst, partial resection and decompression are the goals of surgery because aggressive debulking may lead to neurological compromise. Close imaging follow-up is warranted.
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  • 文章类型: Journal Article
    OBJECTIVE: Retrorectal masses are abnormalities located anatomically in the retrorectal space. A significant proportion are asymptomatic with no malignant potential while others cause symptoms due to mechanical pressure or malignant infiltration. We reviewed and categorised the retrorectal masses encountered over a 30-year time period in a specialist colorectal hospital and describe our management algorithm for consideration by other multidisciplinary teams (MDT).
    METHODS: This was a retrospective analysis of consecutive patients referred between 1984-2019. A detailed review of clinical presentation, imaging features, postoperative histology and impact on morbidity and anorectal function is reported.
    RESULTS: A total of 143 patients with median age of 46 years and female preponderance (74%) were reviewed. The commonest presenting symptom was pain (46%) and all malignant cases had symptoms (n = 17). Over the last decade, more asymptomatic patients have presented with a retrorectal mass (33%, p = 0.04) and more patients are opting for surveillance rather than resection (33%, p = 0.013). Increasing age and lesion size were associated with malignancy (p < 0.05). Radiological features associated with malignancy included: solid/heterogeneous component, lobulated borders or locally invasive. Following surgery, complications included chronic pain (40%), poor wound healing (23%) and bowel dysfunction (10%).
    CONCLUSIONS: The management of retrorectal masses remains complex. There are features, both clinical and radiological, that can help determine the best management strategy. Management should be in a high-volume tertiary centre and preferably through a complex rectal cancer MDT. Long-term sequelae such as chronic pain must be highlighted to patients. We advocate the establishment of an international registry to further record and characterise these rare, potentially troublesome lesions.
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  • 文章类型: Journal Article
    The oral lymphoepithelial cyst (OLC) is an uncommon lesion whose pathogenesis remains poorly understood. The aim of this study was to report the clinicopathologic features of the OLCs and to verify a possible association between OLCs and subgemmal neurogenous plaque (SNP) in the posterior lateral region of the tongue. A retrospective descriptive cross-sectional study was carried out. A total of 106,282 biopsy records of oral and maxillofacial lesions from six oral pathology services in Brazil were analyzed. All cases of OLCs were reviewed, and clinical and histopathological data were collected. Immunohistochemical reactions for S-100 protein were performed to confirm the diagnosis of SNP. Among all lesions, there were 132 (0.11%) cases of OLCs. The series comprised 83 females (62.9%) and 49 males (37.1%), with a 1.7:1 female-to-male ratio and a mean age of 45.8 ± 17.7 years. Most cases involved the tongue (n = 80; 62.0%) and presented clinically as asymptomatic papules or nodules with a yellow or whitish color. Microscopically, most of the cysts were entirely lined by parakeratinized stratified epithelium (n = 89; 67.4%) and filled with desquamated cells, keratin debris, amorphous eosinophilic material, and inflammatory cells in varying amounts. Connection with the epithelium of oral mucosa was observed in 18 cases (13.6%). SNP was found in 9/80 (11.2%) cases involving the tongue. The clinical and demographic features of OLCs were similar to those described in previous studies. Overall, this lesion has a predilection for the posterior region of the tongue of female adults. Clinicians must include the OLC in the differential diagnosis of yellow/white papules and nodules of the oral cavity.
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  • 文章类型: Case Reports
    BACKGROUND: Lateral Periodontal Cyst (LPC) is considered as a rare developmental odontogenic cyst. It is often diagnosed as an incidental radiographic finding, presenting as a circumscribed round radiolucent area between the roots of vital teeth. LPC usually does not present any clinical features. Differentiating the origin of the lesion from an endodontic or periodontal perspective presents as clinical challenge.
    METHODS: A female patient presented with an asymptomatic gingival swelling in the lingual aspect of mandibular anterior region. The associated tooth (#34) was endodontically treated 3 years back. A periapical radiograph showed a well-defined round radiolucency on the tooth. Cone beam computed tomography (CBCT) revealed extensive bone destruction. The lesion was surgically excised and histological examination confirmed the diagnosis of LPC. The site healed satisfactorily post-operatively. The case was followed up for a year without any recurrence seen.
    CONCLUSIONS: LPC is a very rare clinical entity, the diagnosis of which requires a detailed case history taking, clinical and radiographic examination are essential to get proper assessment of the pathology. It is said to originate from either the remnants of dental lamina, reduced enamel epithelium or rests of Malassez. LPC presents with a typical histological picture which ensures the confirmatory diagnosis. Surgical enucleation with thorough curettage is the treatment of choice.
    CONCLUSIONS: By reporting this rare case, we would like to stress to clinicians that there are a wide range of cysts and anatomic structures are present in the canine-premolar region of mandible of which LPC is a rare possibility.
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  • 文章类型: Case Reports
    Rectal mucinous adenocarcinoma is a subtype of colorectal adenocarcinoma, which is more aggressive and prone to invade adjacent normal organs or tissues compared with non-mucinous adenocarcinoma. Retrorectal dermoid cyst is a rare congenital disease, which usually are benign but with a potential for malignant degeneration. In this article, we report a case which presented a rectal mucinous adenocarcinoma invading into retrorectal dermoid cysts, indicating that besides adjacent normal organs or tissues, malignancies can also invade adjacent tumors, making their diagnosis and management more complicated. In such cases, double primary tumors should be considered, and they should be removed surgically.
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  • 文章类型: Journal Article
    BACKGROUND: The best approach for resecting epidermoid cysts is still controversial. We describe a case of an epidermoid cyst in which laparoscopic resection was performed successfully.
    METHODS: 63 × 55-mm well-defined cystic mass was incidentally detected by computed tomography in the presacral cavity of a 50-year-old woman during evaluation for upper abdominal pain. Magnetic resonance imaging showed a cystic tumor with a low signal intensity on T1-weighted images and, high signal on T2-weighted images in the left dorsal side of the rectum. This tumor was diagnosed as a developmental cyst, and laparoscopic resection was performed. Resection of the tumor was performed with negative margins. This tumor was histopathologically diagnosed as an epidermoid cyst. There was no evidence of malignancy, and no postoperative event or signs of recurrence occurred 6 months postoperatively.
    CONCLUSIONS: In our patient, there was no difficulty in the field of view and forceps operability during laparoscopic surgery. Furthermore, it is possible to perform laparoscopic surgery with minimal damage to the muscles, nerves, and rectum, leading to the preservation of anal function.
    CONCLUSIONS: Laparoscopic resection of an epidermoid cyst may be a better option in carefully selected cases with consideration of the tumor size and location.
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