背景:纤维瘤(DF)是一种以肌成纤维细胞和成纤维细胞的强克隆性增殖为特征的疾病。我们描述了一个模仿乳腺肿瘤的DF病例,同时回顾了临床表现的文献,诊断过程,以及这种战斗疾病的治疗过程。
方法:一名34岁女性患者,在左乳房上象限的交界处有乳房肿块。DF诊断后,决定进行与象限后重建相关的左乳房切片切除术,免疫组织化学和结果与DF相容。
结论:临床表现为实性肿块,通常无痛,偶尔粘附在胸壁上。每个患者的治疗策略应该是理想化的。因此,有可能进行根治性手术切除和/或放疗,手术后可进行放疗。
BACKGROUND: Desmoid fibroma (DF) is a disorder characterized by strong clonal proliferation of myofibroblasts and fibroblasts. We describe a case of DF that mimicked a breast tumor, along with a review of the literature on the clinical manifestation, diagnostic process, and course of therapy for this combative disease.
METHODS: A 34-year-old female patient with breast lump at the junction of the upper quadrants of the left breast. After the diagnosis of DF, it was decided to perform a sectorectomy of the left breast associated with post-quadrant reconstruction, with immunohistochemistry and findings compatible with DF.
CONCLUSIONS: Clinically manifests as a solid mass that is often painless and occasionally adherent to the chest wall. A treatment strategy should be idealized for each patient. Thus, there is the possibility of performing radical surgery for resection and/or radiotherapy, and surgery may be followed by radiotherapy.