■目的是检查在印度严重急性呼吸道综合症冠状病毒2(SARS-CoV-2)大流行期间因冠状病毒病-2019(COVID-19)感染而入住重症监护病房的孕妇的结局。该研究的主要结果是第30天的产妇死亡率。次要结果是重症监护病房(ICU)和住院时间,胎儿死亡率和早产。
■这是一项回顾性多中心队列研究。获得了道德许可。在2020年3月1日至10月31日期间,所有15-45岁的孕妇因SARS-CoV-2感染入院,包括2021年。
■数据来自9个中心和211例确诊为COVID-19的ICU产科患者。根据室内空气入院时的SpO2(外周血氧饱和度)水平将他们分为两组,也就是说,正常SpO2组(SpO2>90%)和低SpO2组(SpO2<90%)。平均年龄(30.06±4.25)岁,胎龄36±8周。孕产妇死亡率为10.53%。胎儿死亡和早产率分别为7.17和28.22%,分别。平均ICU和住院时间(LOS)分别为6.35±8.56和6.78±6.04天,分别。孕产妇死亡率(6.21比43.48%,p<0.001),早产(26.55vs52.17%,p=0.011)和胎儿死亡(5.08vs26.09%,p=0.003)在低SpO2组中明显更高。
感染COVID-19的危重孕妇的总体孕产妇死亡率为10.53%。早产和胎儿死亡率分别为28.22%和7.17%,分别。入院时低SpO2(<90%)的患者与正常SpO2的患者相比,这些不良的母体和胎儿结局明显更高。
■SinhaS,保罗·G,沙巴,KarmataT,PaliwalN,DobariyaJ,etal.回顾性分析印度重症监护病房(Preg-CoV)的SARS-CoV-2感染孕妇的临床特征和结局:一项多中心研究。印度J暴击护理中心2024;28(3):265-272。
UNASSIGNED: The aim was to examine the outcomes of pregnant women admitted to intensive care unit with coronavirus disease-2019 (COVID-19) infection during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in India. The primary outcome of the study was maternal mortality at day 30. The secondary outcomes were the intensive care unit (ICU) and hospital length of stay, fetal mortality and preterm delivery.
UNASSIGNED: This was a retrospective multicentric cohort study. Ethical clearance was obtained. All pregnant women of the 15-45-year age admitted to ICUs with SARS-CoV-2 infection during 1st March 2020 to 31st October, 2021 were included.
UNASSIGNED: Data were collected from nine centers and for 211 obstetric patients admitted to the ICU with a confirmed diagnosis of COVID-19. They were divided in to two groups as per their SpO2 (saturation of peripheral oxygen) level at admission on room air, that is, normal SpO2 group (SpO2 > 90%) and low SpO2 group (SpO2 < 90%). The mean age was (30.06 ± 4.25) years and the gestational age was 36 ± 8 weeks. The maternal mortality rate was10.53%. The rate of fetal death and preterm delivery was 7.17 and 28.22%, respectively. The average ICU and hospital length of stay (LOS) were 6.35 ± 8.56 and 6.78 ± 6.04 days, respectively. The maternal mortality (6.21 vs 43.48%, p < 0.001), preterm delivery (26.55 vs 52.17%, p = 0.011) and fetal death (5.08 vs 26.09%, p = 0.003) were significantly higher in the low SpO2 group.
UNASSIGNED: The overall maternal mortality among critically ill pregnant women affected with COVID-19 infection was 10.53%. The rate of preterm birth and fetal death were 28.22 and 7.17%, respectively. These adverse maternal and fetal outcomes were significantly higher in those admitted with low SpO2 (<90%) at admission compared with those with normal SpO2.
UNASSIGNED: Sinha S, Paul G, Shah BA, Karmata T, Paliwal N, Dobariya J, et al. Retrospective Analysis of Clinical Characteristics and Outcomes of Pregnant Women with SARS-CoV-2 Infections Admitted to Intensive Care Units in India (Preg-CoV): A Multicenter Study. Indian J Crit Care Med 2024;28(3):265-272.