■我们旨在探索简单有效的临床参数或组合,以预测川崎病(KD)儿科患者的冠状动脉扩张和动脉瘤形成。设计和方法:这项回顾性队列研究包括1月的KD患儿,2013年至12月,2022年。收集了多个人口统计学和临床数据,整理,并根据病历计算。然后将其分为冠状动脉扩张和动脉瘤形成组和非冠状动脉扩张和动脉瘤形成组。将淋巴细胞-C反应蛋白比率(LCR)转化为其自然对数并表示为lnLCR。
■在1:3倾向评分匹配(PSM)后,共有64名KD儿科患者纳入本队列研究。对于lnLCR的每个单位增加,冠状动脉扩张和动脉瘤形成的可能性下降到原始值的0.419倍。lnLCR结合白蛋白(ALB)的受试者工作特征(ROC)曲线下面积,ALB,将KD患儿分为冠状动脉扩张组和动脉瘤形成组的lnLCR分别为0.781,0.692和0.743.结论:入院时LCR联合ALB是KD患儿冠状动脉扩张和动脉瘤形成的有希望的预测指标。
UNASSIGNED: We aimed to explore simple and effective clinical parameters or combinations to predict coronary artery dilation and aneurysm formation in pediatric patients with Kawasaki disease (KD).
UNASSIGNED: This retrospective cohort study included pediatric patients with KD from January, 2013 to December, 2022. Multiple demographic and clinical data were collected, collated, and calculated from the medical records. Then they were divided into the coronary artery dilation and aneurysm formation group or the non-coronary artery dilation and aneurysm formation group. Lymphocyte-C-reactive protein ratio (LCR) was transformed into its natural logarithm and expressed as lnLCR.
UNASSIGNED: A total of 64 pediatric patients with KD were enrolled in this cohort study after 1:3 propensity score matching (PSM). For each unit increase in lnLCR, the possibility of coronary artery dilation and aneurysm formation decreased to 0.419 times the original value. The areas under the receiver operating characteristic (ROC) curves of lnLCR combined with albumin (ALB), ALB, and lnLCR to classify pediatric patients with KD into the coronary artery dilation and aneurysm formation group were 0.781, 0.692, and 0.743, respectively.
UNASSIGNED: LCR combined with ALB upon admission is a promising predictor of coronary artery dilation and aneurysm formation in pediatric patients with KD.