■参考间隔是识别异常实验室测试结果的重要方法工具。全血细胞计数参考值可用于解释全血细胞计数(CBC)结果并做出临床决策。但是这些价值还没有为Asella镇的老年病学确立。因此,这项研究旨在建立来自Asella镇的老年参与者/受试者的全血细胞计数(CBC)参数的参考间隔(RIs),埃塞俄比亚东南部。
■一项基于社区的横断面研究于2019年12月至2020年5月进行。使用面试官管理的问卷从342名符合条件的老年参与者中收集有关社会人口统计学和其他特征的数据。重量,高度,并测量了生命体征,收集8mL血样。筛查测试,如艾滋病毒,HBsAg,HCV,梅毒,大便检查,并进行尿液分析。使用Sysmexkx-21血液学分析仪测量血液学参数。数据采用SPSS21版软件进行分析。非参数独立Kruskal-Wallis检验和Wilcoxon秩和检验(Mann-WhitneyU检验)用于比较年龄组和性别之间的参数。97.5和2.5百分位数是该人群的参考上限和下限。
■根据研究结果,红细胞的参考间隔,白细胞,血小板计数,血红蛋白(HGB),男性老年患者的血细胞比容(HCT)为3.8-5.85×1012/L,3.1-9.66×109/L,115.8-353×109/L,12.4-17.76g/dL,35.06-50.2%,分别。女性各值为3.94-5.48×1012/L,3.13-8.4×109/L,137.5-406×109/L,12.5-16.4g/dL,和36.09-48.2%。大多数血液学参数显示两种性别之间的显着差异(p值<0.05)。
■准确的性别和年龄参考区间对于管理患者健康至关重要。目前的研究提供了必要的CBC血液学参数,可以帮助临床医生解释实验室结果,并可以提高老年人群的医疗质量。因此,在老年病学设置中使用当前的RI更相关。
UNASSIGNED: Reference intervals are an important method tool for identifying abnormal laboratory test results. Complete blood count reference values are useful to interpret complete blood count (CBC) results and make clinical decisions, but these values have not been established for geriatrics in Asella town. Therefore, this study aimed to establish reference intervals (RIs) for complete blood count (CBC) parameters from geriatric participants/subjects in Asella town, Southeast Ethiopia.
UNASSIGNED: A community-based cross-sectional study was conducted from December 2019 to May 2020. An interviewer-administered questionnaire was used to collect data on sociodemography and other characteristics from 342 eligible geriatric participants. Weight, height, and vital signs were measured, and 8 mL of blood sample was collected. Screening tests such as HIV, HBsAg, HCV, syphilis, stool examination, and urinalysis were performed. The hematological parameter was measured using a Sysmex kx-21 hematology analyzer. The data were analyzed using SPSS version 21 software. The non-parametric independent Kruskal-Wallis test and Wilcoxon rank-sum test (Mann-Whitney U test) were used to compare the parameters between age groups and genders. The 97.5 and 2.5th percentile were the upper and lower reference limit for the population.
UNASSIGNED: According to the study\'s findings, the reference intervals of red blood cell, white blood cell, platelet count, hemoglobin (HGB), and hematocrit (HCT) in male geriatrics were 3.8-5.85 × 1012/L, 3.1-9.66 × 109/L, 115.8-353 × 109/L, 12.4-17.76 g/dL, and 35.06-50.2%, respectively. The respective values for women were 3.94-5.48 × 1012/L, 3.13-8.4 × 109/L, 137.5-406 × 109/L, 12.5-16.4 g/dL, and 36.09-48.2%. Most of the hematological parameters showed significant differences between the two genders (p value <0.05).
UNASSIGNED: Accurate gender and age-specific reference intervals are crucial in managing patient health. The current study offers essential CBC hematological parameters that can assist clinicians in interpreting laboratory results and can improve healthcare quality in the geriatric population. Therefore, it is more relevant to use the current RIs in the geriatric set-up.