collision

碰撞
  • 文章类型: Journal Article
    与架空线碰撞和电死造成的鸟类死亡,如电源线和电话线,其中,与全球各种鸟类物种的减少有关。具体来说,架空线碰撞对Canarianhoubarawast(Chlamydotisundulatafuertaventurae)的保护构成了重大威胁,加那利群岛特有的濒危亚种。这项研究的重点是与架空线相撞的Canarianhoubara芽的事后发现,为这些鸟类提供碰撞后结果的见解。对9个Canarianhoubara芽进行的完整标准化尸检显示,在所有情况下,创伤都是死亡原因。与创伤相关的最显著的总体病变包括骨折,软组织撕裂,出血,脱位,和血液腔。腹股沟区,胸部,和翅膀是更频繁受到影响的身体区域。组织病理学,免疫组织化学,昆虫学分析证实,许多鸟类在最初的创伤中幸存下来。我们得出的结论是,当哈巴拉·赫斯特德与架空线相撞时,它经常在最初的创伤中幸存下来,存活时间从几分钟到几小时不等。组织病理学,免疫组织化学,或昆虫学分析可能有助于估计创伤和死亡之间的时间间隔。
    The mortality of birds resulting from collisions and electrocutions with overhead lines, such as power lines and phone lines, among others, has been implicated in the decline of various avian species globally. Specifically, overhead line collisions pose a significant threat to the conservation of the Canarian houbara bustard (Chlamydotis undulata fuertaventurae), an endangered subspecies endemic to the Canary Islands. This study centers on the postmortem findings of Canarian houbara bustards that have collided with overhead lines, providing insights into the post-collision outcomes for these birds. A complete standardized necropsy of nine Canarian houbara bustards revealed that trauma was the cause of death in all cases. The most notable gross lesions associated with trauma included bone fractures, soft tissue lacerations, hemorrhages, luxations, and hemocoelom. The inguinal area, chest, and wings were the body regions more frequently affected. A histopathology, immunohistochemistry, and entomology analysis confirmed that numerous birds survived the initial trauma. We concluded that when a houbara bustard collides with an overhead line, it frequently survives the initial trauma, with a survival time ranging from minutes to hours. The histopathology, immunohistochemistry, or entomologic analysis may be helpful to approximate the timing interval between trauma and death.
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  • 文章类型: Journal Article
    姿势稳定对于有效地与我们的环境互动至关重要。人类先发制人地调整自己的姿势以抵消即将发生的干扰,例如在与移动物体交互期间遇到的那些,一种被称为预期姿势调整(APAs)的现象。APA被认为受到预测模型的影响,该模型通过视网膜运动和视网膜外信号结合了对象运动。在我们以前的工作的基础上,研究了与移动物体的感知动量相关的APA,在这里,我们探索了不同视野区域内物体运动对人类预测运动的能力的影响,并为虚拟运动物体和肢体之间的接触准备了APA。参与者在不同的注视条件下与向他们移动的物体进行交互。在一个条件下,参与者固定在运动物体的中心点(中央固定)或左右(外围固定),而在另一个,他们以平滑的追踪眼球运动(SPEM)跟随移动的物体。我们发现APA在中央固定条件下的幅度最小,并且在SPEM和外周固定条件之间APA没有显着差异。这表明视觉系统可以准确地感知周围视觉中物体的运动,以实现姿势稳定。使用贝叶斯模型平均,我们还评估了不同凝视变量的贡献,例如眼睛速度和增益(眼睛和物体速度的比率),并表明眼睛速度和增益信号都是APA的重要预测因子。一起来看,我们的研究强调了动眼信号在调节APA中的作用。
    Postural stabilization is essential to effectively interact with our environment. Humans preemptively adjust their posture to counteract impending disturbances, such as those encountered during interactions with moving objects, a phenomenon known as anticipatory postural adjustments (APAs). APAs are thought to be influenced by predictive models that incorporate object motion via retinal motion and extra-retinal signals. Building on our previous work that examined APAs in relation to the perceived momentum of moving objects, here we explored the impact of object motion within different visual field sectors on the human capacity to anticipate motion and prepare APAs for contact between virtual moving objects and the limb. Participants interacted with objects moving towards them under different gaze conditions. In one condition, participants fixated on either a central point (central fixation) or left-right of the moving object (peripheral fixation), while in another, they followed the moving object with smooth pursuit eye movements (SPEM). We found that APAs had the smallest magnitude in the central fixation condition and that no notable differences in APAs were apparent between the SPEM and peripheral fixation conditions. This suggests that the visual system can accurately perceive motion of objects in peripheral vision for posture stabilization. Using Bayesian Model Averaging, we also evaluated the contribution of different gaze variables, such as eye velocity and gain (ratio of eye and object velocity) and showed that both eye velocity and gain signals were significant predictors of APAs. Taken together, our study underscores the roles of oculomotor signals in modulation of APAs.
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  • 文章类型: Journal Article
    背景:在密闭水域,船只有很高的着陆风险,联系人,沉没和险些失踪。在这样的水域,海上交通密集,水道狭窄,深度有限,潮汐和水流不断变化。
    方法:从2009年至2019年,在塞纳河河口调查了75起事故。研究了天气条件和感知的疲劳。2020年5月至6月,114名海员,34名飞行员和80名机长,答复了一份调查问卷,重点是使用试点便携式设备(PPU)和电子海图显示信息系统(ECDIS)。
    结果:75起事故相当于每年平均6.8±3.2起事故。环境是最常见的事故(35%,n=26)其次是与码头的接触事故(25%,n=19),操纵时在船只或拖船之间(8%,n=6)或航行时(1%,n=1)。没有船只损失,也没有船员死亡。在恶劣的天气条件下,事故比正常情况下多76%(4.4±2.5事故/10,000运动与2.5±1.9事故/10,000运动,p<0.03)。几乎所有的事故(96%)都与人为判断失误(81%)有关,或疏忽(53%),或两者(39)。感觉疲劳可能是6起事故的原因。只有3起事故与机械原因有关。通过问卷调查,69%的飞行员抱怨在掌握设备和软件方面存在困难。他们在导航时被影响注意力的警报分散了注意力。他们要求在模拟器上训练。关于船长,83%的人对ECDIS设备感到满意,但只有20%的人能够正确配置ECDIS。
    结论:在塞纳河河口,在11年的研究中发生了75起事故。危险因素是恶劣的天气条件和人为错误。PPU和ECDIS被认为是预防事故的有用工具。然而,飞行员和机长要求对他们的使用进行更彻底的培训。
    BACKGROUND: In confined waters, ships run a high risk of groundings, contact, sinkings and near misses. In such waters the maritime traffic is dense, the waterway is narrow, the depth is limited, and tides and currents are constantly changing.
    METHODS: From 2009-2019, 75 accidents were investigated in the estuary of the Seine. Weather conditions and perceived fatigue were studied. From May to June 2020, 114 seafarers, 34 pilots and 80 captains, responded to a questionnaire focusing on the use of Pilot Portable Units (PPU) and Electronic Chart Display Information Systems (ECDIS).
    RESULTS: The 75 accidents corresponded to an average of 6.8 ± 3.2 accidents per year. Groundings were the most frequent accidents (35%, n = 26) followed by contact accidents with the quayside (25%, n = 19), between ships or tugs while manoeuvring (8%, n = 6) or while sailing (1%, n = 1). There was no loss of vessels nor fatalities of crew members. In poor weather conditions, there were 76% more accidents than in normal conditions (4.4 ± 2.5 accidents/10,000 movements versus 2.5 ± 1.9 accidents/10,000 movements, p < 0.03). Almost all the accidents (96%) were related to human errors of judgment (81%), or negligence (53%), or both (39). Perceived fatigue was probably in cause in 6 accidents. Only 3 accidents were related to mechanical causes. Through the questionnaires, 69% of the pilots complained of difficulties in mastering the devices and software. They felt distracted by alarms which affected their attention while navigating. They requested training on a simulator. Concerning ship captains, 83% felt comfortable with ECDIS devices yet only 20% were able to configure the ECDIS correctly.
    CONCLUSIONS: In the Seine estuary, 75 accidents occurred within the 11 year-study. Risk factors were poor weather conditions and human error. PPU and ECDIS were considered as useful tools in the prevention of accidents. However, pilots and captains requested more thorough training in their use.
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  • 文章类型: Journal Article
    目的:天然提取多糖,如瓜尔胶,是环保浮选试剂的有希望的候选人。假设亚毫米气泡与疏水性石墨表面的碰撞动力学,泡沫和表面之间形成的薄液膜的稳定性受瓜尔胶吸附层的影响。
    方法:使用重量分析(带有耗散的石英晶体微天平)和成像(原子力显微镜)技术的组合来研究瓜尔胶在石墨表面的吸附,而高速相机成像允许以毫秒分辨率直接观察瓜尔胶改性石墨表面的气泡碰撞过程。
    结果:原子力显微镜形貌图像揭示了吸附在石墨表面的瓜尔胶分子的瓜尔胶浓度依赖性互连网络。这些吸附分子在低表面覆盖率下,改变了石墨表面的润湿性,导致薄膜排水时间延长一个数量级,在较高的表面覆盖率下成功地防止气泡附着到石墨表面。最重要的是,吸附层改变了气泡从石墨表面反弹的强度。这种增强的气泡弹跳可以与薄膜排水时间相关,并用于预测成功的气泡颗粒附着。
    OBJECTIVE: Naturally extracted polysaccharides, such as guar gum, are promising candidates for environmentally friendly flotation reagents. It is hypothesized that the kinetics of collision of sub- to millimeter gas bubbles with a hydrophobic graphite surface, and the stability of thin liquid film formed between the bubble and surface is affected by an adsorbed layer of guar gum.
    METHODS: A combination of gravimetric (quartz crystal microbalance with dissipation) and imaging (atomic force microscopy) techniques was used to investigate the adsorption of guar gum on graphite surface, while high-speed camera imaging allowed for direct observation of the bubble collision process with guar gum-modified graphite surfaces with millisecond resolution.
    RESULTS: Atomic force microscope topography images revealed a guar gum concentration-dependent interconnected network of guar gum molecules adsorbed at graphite surface. These adsorbed molecules at low surface coverage, changed the wettability of the graphite surface, resulting in a film drainage time longer by an order of magnitude, while at higher surface coverage successfully prevented bubble attachment to the graphite surface. Most importantly, the adsorbed layer changed the strength of the bubble\'s bouncing off the graphite surface. This enhanced bubble bouncing can be correlated with the film drainage time and used to predict a successful bubble-particle attachment.
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  • 文章类型: Journal Article
    概述了人类转向和避免碰撞的行为研究,包括光流的处理,光学隐现和人类移动注视系统的作用。然后考虑自动驾驶汽车(AV)从网格型道路网络移动到复杂的城市内街道并与人类驾驶员互动时可能出现的问题。行人和骑自行车的人。对这些相互作用的人类处理和AV处理进行了比较。这就提出了AV控制系统是否需要更紧密地模仿人类视觉处理的问题,并强调了AV系统需要开发一种“道路使用者理论”,允许将意图归因于其他驾驶员,骑自行车的人或行人。建议为AVs制定“道路使用者理论”的指南。
    An overview is provided of behavioral research into human steering and collision avoidance including the processing of optic flow, optical looming and the role of the human mobile gaze system. A consideration is then made of the issues that may occur for autonomous vehicles (AV) when they move from grid-type road networks into complex inner-city streets and interact with human drivers, pedestrians and cyclists. Comparisons between human processing and AV processing of these interactions are made. This raises issues as to whether AV control systems need to mimic human visual processing more closely and highlights the need for AV systems to develop a \"theory of road users\" that allows attribution of intent to other drivers, cyclists or pedestrians. Guidelines for the development of a \"theory of road users\" for AVs are suggested.
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  • 文章类型: Journal Article
    背景:评估姿势控制对于评估脑震荡后的运动功能很重要。用于姿势控制评估的数据通常不采用所进行的运动,年龄,或者考虑运动员的性别。在做出回归决策时,这些变量可能很重要。
    目的:本研究使用BTrackS数据库来检查不同类型运动的运动员在姿势控制方面的差异以及性别和年龄的差异。
    方法:采用单向方差分析和事后检验对9093名高中至大学运动员(14-22岁)的BTrackS数据进行了检查,以比较运动类型之间的CoP路径长度。适度分析用于测试性别和年龄对CoP/BMI比率的交互影响。
    结果:在运动类型之间观察到显着差异,F(3,9089)=42.4,p<.001,η2=0.014。事后测试表明,与接触(M=23.4,SD=7.4)相比,碰撞(M=25.0,SD=7.6)运动运动员表现出明显更高的CoP指标,有限接触(M=22.9,SD=6.9),非接触(M=23.0,SD=7.4)运动员。其他运动类型之间没有差异(p>.20)。显著的平均性别差异(Mmale=0.924,Mfemale=0.898,p<.001)和与年龄的二次关联,观察到(β=-0.042,p<.001)。Further,这些年龄差异的大小随着年龄的增加而减小(β=0.011,p<.001)。对于线性项(β=0.020,p<.001)和二次项(β=-0.006,p<.001),年龄和性别的交互作用显着。
    结论:运动员在运动类型时表现出不同的姿势控制,年龄,考虑到了性。该数据具有临床意义,因为这表明碰撞运动运动员的规范姿势控制数据应根据所进行的运动类型从数据中得出,年龄,和运动员的性别。
    Assessing postural control is important for the assessment of motor function after concussion. Data used for postural control assessment typically do not take the sport played, age, or sex of the athlete into consideration. It is plausible these variables may be significant when making return-to-play decisions.
    This study used the BTrackS database to examine differences in postural control in athletes playing different types of sports and across sex and age.
    BTrackS data from 9093 high school to college-aged athletes (aged 14-22 years) were examined employing a One-way ANOVA with a post-hoc test to compare CoP path length between sport types. A moderation analysis was used to test interaction effects of sex and age on a CoP/BMI ratio.
    Significant differences were observed between sport types, F(3,9089) = 42.4, p <.001, η2 = 0.014. Post hoc tests indicated that collision (M = 25.0, SD = 7.6) sport athletes exhibited significantly higher CoP measures compared to the contact (M = 23.4, SD = 7.4), limited contact (M = 22.9, SD = 6.9), and non-contact (M = 23.0, SD = 7.4) athletes. There was no difference between other sport types (p >.20). A significant mean sex difference (Mmale = 0.924, Mfemale = 0.898, p <.001) and a quadratic association with age, (β = -0.042, p <.001) was observed. Further, magnitude of those age differences decreased with age (β = 0.011, p <.001). An interaction of age and sex was significant for linear (β = 0.020, p <.001) and quadratic terms (β = -0.006, p <.001).
    Athletes exhibited different postural control when the type of sport, age, and sex was taken into consideration. This data possess clinical significance as this suggests that normative postural control data for collision sport athletes should be derived from data based upon type of sport played, age, and sex of the athlete.
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  • 文章类型: Journal Article
    BACKGROUND: Impaired driving is a public health issue, yet little is known concerning the prevalence of substance use in drivers involved in off-road vehicle crashes. The goal of the present study was to describe the demographics and prevalence of alcohol and drug use in drivers of off-road vehicle crashes.
    METHODS: In this observational substudy, we collected clinical and toxicological data on all moderately or severely injured off-road vehicle drivers who had blood samples obtained within 6 h of the crash. Clinical data were extracted from patients\' medical charts and toxicology analyses were performed for blood alcohol, cannabinoids, recreational drugs, and impairing medications.
    RESULTS: Thirty-three injured drivers met the inclusion criteria. The mean age was 37.6 ± 13.4 years and 79% were male. Blood alcohol was detected in 58% of drivers and 42% of these were above the legal limit. Tetrahydrocannabinol was positive in 12% of drivers, and 18% were positive for recreational drugs. Opiates were detected in 21% of drivers. Overall, 85% were positive for at least one substance and 39% tested positive for multiple substances.
    CONCLUSIONS: This study presents the first evidence of alcohol and drug use in off-road vehicle drivers after cannabis legalization in Canada. Our results show that over half of drivers in off-road vehicle crashes test positive for alcohol and 30% tested positive for THC, cocaine, or amphetamines. Opiates are also commonly detected in off-road vehicle drivers. Emergency department (ED) visits resulting from drug driving of off-road vehicles serve as an opportunity for screening, initiating treatment, and connecting patients to interventions for substance use disorders.
    UNASSIGNED: CONTEXTE: La conduite avec facultés affaiblies est un problème de santé publique, mais on sait peu de choses sur la prévalence de la toxicomanie chez les conducteurs impliqués dans des accidents de la route. L’objectif de la présente étude était de décrire la démographie et la prévalence de la consommation d’alcool et de drogues chez les conducteurs de véhicules hors route. MéTHODES: Dans le cadre de cette sous-étude observationnelle, nous avons recueilli des données cliniques et toxicologiques sur tous les conducteurs de véhicules hors route ayant subi des blessures modérées ou graves qui avaient reçu des échantillons de sang dans les 6 heures suivant l’accident. Les données cliniques ont été extraites des dossiers médicaux des patients et des analyses toxicologiques ont été effectuées pour l’alcool dans le sang, les cannabinoïdes, les drogues récréatives et les médicaments pour les facultés affaiblies. RéSULTATS: Trente-trois conducteurs blessés répondaient aux critères d’inclusion. L’âge moyen était de 37,6 13,4 ans et 79 % étaient des hommes. L’alcool dans le sang a été détecté chez 58 % des conducteurs et 42 % d’entre eux dépassaient la limite légale. Le tétrahydrocannabinol était positif chez 12 % des conducteurs et 18 % étaient positifs aux drogues récréatives. Des opiacés ont été détectés chez 21 % des conducteurs. Dans l’ensemble, 85 % étaient positifs pour au moins une substance et 39 % étaient positifs pour plusieurs substances.
    CONCLUSIONS: Cette étude présente les premières preuves de la consommation d’alcool et de drogues chez les conducteurs de véhicules hors route après la légalisation du cannabis au Canada. Nos résultats montrent que plus de la moitié des conducteurs de véhicules hors route ont un résultat positif au test de dépistage de l’alcool et 30 % ont un résultat positif au test de dépistage du THC, de la cocaïne ou des amphétamines. Les opiacés sont également couramment détectés chez les conducteurs de véhicules hors route. Les visites aux services d’urgence (SU) découlant de la conduite de véhicules hors route avec facultés affaiblies par la drogue constituent une occasion de dépistage, d’amorcer un traitement et de mettre les patients en contact avec des interventions pour les troubles liés à la consommation de substances.
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  • 文章类型: Journal Article
    本研究旨在评估使用微传感器技术(MST,弹射器矢量)在一级国家橄榄球联盟(RU)小队的背景下,由44名球员组成。在八次测试匹配中评估了MST单位对检测CI和Scrums的敏感性,通过与视频分析获得的匹配数据进行比较。本文首次评估了MST对RU中发生的全部技能CI的敏感性,包括评估“非性能”冲突,例如偶然的碰撞或犯规。对铲球的敏感性(52.9-84.9%)和落球命中率(53.3-87.2%)低于先前的研究,尽管球携带(71.9-93.5%)对既定结果的敏感性大致相似。MST检测Scrums的灵敏度大大低于以前的发现,明显的位置变化(51.4-91.5%)。应考虑进一步改进MST软件,以促进对RU性能和伤害风险的有效监控。另一个发现是,视频分析通常证明了令人满意的内部可靠性。此结果支持使用视频分析作为评估RU性能的可靠方法,包括CI。
    This study sought to assess the validity of contact involvement (CI) detection using microsensor technology (MST, Catapult Vector) within the context of a Tier One national rugby union (RU) squad, consisting of 44 players. Sensitivity of MST units to detect CI and scrums was assessed in eight test matches, by comparison with match data obtained by video analysis. This paper is the first to assess the sensitivity of MST to the full range of skilled CI which occur in RU, including evaluating \"non-performance\" collisions, such as incidental collisions or foul play. Sensitivity to tackles made (52.9-84.9%) and ruck hits (53.3-87.2%) was lower than previous research, although ball carries (71.9-93.5%) showed broadly similar sensitivity to established results. The sensitivity of the MST to detect scrums was substantially lower than previous findings, with large positional variation evident (51.4-91.5%). Further refinement of MST software should be considered in order to facilitate valid monitoring of RU performance and injury risk. An additional finding was that video analysis generally demonstrated satisfactory intrarater reliability. This result supports the use of video analysis as a reliable method of assessing RU performance, including CI.
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  • 文章类型: Journal Article
    随着许多大型鲸鱼种群的大量增加,伴随着全球航运和娱乐船只活动的增长,鲸鱼和船只之间的负面互动正在增加,这并不奇怪。这里,通过确定它们的运动轨迹响应于迎面而来的船只的变化是否转化为船只回避来评估座头鲸(Megapteranovaeangliae)的迁徙群体与船只之间的碰撞风险。假设团体会实施逃避应对策略,使用诸如船速之类的线索,轨迹,接近度,并接收到噪声水平以告知其响应幅度。然而,许多团体对接近的船只没有反应,因此船只不得不采取回避行动。这项研究表明,当船只和鲸鱼有可能相撞时,座头鲸不太可能采取足够的回避行动。因此,在制定风险管理战略时,减少鲸鱼和船只相遇率的缓解措施可能是最有效的。
    With the substantial increase in many large whale populations, paired with the rise in global shipping and recreational vessel activity, it is not surprising that negative interactions between whales and vessels are increasing. Here, the collision risk between migrating groups of humpback whales (Megaptera novaeangliae) and vessels was assessed by determining if changes in their movement trajectories in response to an oncoming vessel translated to vessel avoidance. It was assumed groups would implement an escape response strategy, using cues such as the vessel speed, trajectory, proximity, and received level of noise to inform their response magnitude. However, many groups were unresponsive to an approaching vessel such that the vessel had to take evasive action. This study shows that humpback whales are not likely to take sufficient avoidance action when there is a potential for a vessel and whale to collide. Therefore, when developing a risk management strategy, mitigation measures that reduce the encounter rate between whales and vessels are likely to be the most effective.
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  • 文章类型: Journal Article
    背景:多种肿瘤从不同的细胞类型产生并在脑内同时发生是极不寻常的。尚不清楚脑膜瘤和胶质母细胞瘤的共存是否以任何方式联系在一起,或者它们的同时出现仅仅是巧合。
    目的:我们对并发脑膜瘤和胶质母细胞瘤的发生进行了全面的文献综述,以阐明可能构成这种共存的基本概念。
    方法:我们在GoogleScholar中搜索了关于胶质母细胞瘤与脑膜瘤共存的文章,PubMed,还有Scopus.首先,最初的文献检索是针对研究选择和数据收集过程进行的.评价标题和摘要后,论文被选中。
    结果:我们分析了21项研究,描述了23例同时患有胶质母细胞瘤和脑膜瘤的患者。男性患者10例(47.6%),女性患者13例(61.9%)。诊断时患者的平均年龄为61岁(30至86岁)。在17个案例中,两种肿瘤均位于同一半球(80.9%).在5个案例中,他们在另一个半球(23.8%),在一个案例中,胶质母细胞瘤位于左半球,嗅觉脑膜瘤5例,他们在另一个半球(23.8%),在一个案例中,胶质母细胞瘤位于左半球,嗅脑膜瘤位于前颅窝。在61.9%的病例中,头痛是主要症状。
    结论:了解胶质母细胞瘤和脑膜瘤共存带来的独特挑战对于制定有效的治疗策略至关重要。对这一罕见事件中涉及的潜在分子机制和遗传因素的进一步调查可以为针对每个患者的特定需求量身定制的个性化治疗铺平道路。
    It is extremely unusual for multiple tumors to arise from different cell types and occur at the same time inside the brain. It is still unknown whether or not the coexistence of meningioma and glioblastoma is connected in any way or if their simultaneous appearance is merely a coincidence.
    We conduct a comprehensive literature review on cases of concurrent meningioma and glioblastoma occurrence to elucidate the underlying concepts that may constitute this coexistence.
    We searched for articles on the topic of glioblastoma coexisting with meningioma in Google Scholar, PubMed, and Scopus. First, the initial literature searches were conducted for study selection and the data collection processes. After evaluating the title and abstract, the papers were selected.
    We analyzed 21 studies describing 23 patients who had both glioblastoma and meningioma. There were ten male patients (47.6 %) and thirteen female patients (61.9 %). The mean age of patients at diagnosis was 61 years old (the range 30 to 86). In 17 cases, both tumors were in the same hemisphere (80.9 %). In 5 cases, they were in the other hemisphere (23.8 %), and in one case, the glioblastoma was in the left hemisphere and the olfactory meningioma was In 5 cases, they were in the other hemisphere (23.8 %), and in one case, the glioblastoma was in the left hemisphere and the olfactory meningioma was in the anterior cranial fossa. In 61.9 % of cases, headache was the predominant symptom.
    Understanding the unique challenges posed by the coexistence of glioblastoma and meningioma is crucial for developing effective treatment strategies. Further investigation into the underlying molecular mechanisms and genetic factors involved in this rare occurrence could pave the way for personalized therapies tailored to each patient\'s specific needs.
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