clinical psychiatry

临床精神病学
  • 文章类型: Journal Article
    目标:COVID-19大流行要求全球精神卫生临床医生过渡到通过远程医疗提供护理。这项研究旨在了解客户对远程健康心理健康服务的满意度和态度。
    方法:70名曾因情绪和焦虑症就诊的成年人,并参加了至少一次与心理学家或精神科医生的远程医疗咨询,完成了匿名在线调查。
    结果:大多数参与者(81.5%)报告对COVID-19大流行期间提供的远程保健精神保健感到满意。然而,在接受远程保健和面对面精神保健的参与者中,总体满意度明显更高,与仅通过远程医疗接受护理的参与者相比。据报道,远程医疗保健的优势包括便利和更多接触心理健康临床医生的机会。然而,远程医疗的缺点包括与临床医生建立融洽关系和通过远程医疗表达自己的困难更大。
    结论:虽然客户对针对情绪和焦虑症的远程保健精神保健的满意度普遍较高,临床医生应该从客户的角度考虑远程医疗的局限性。特别是,可能需要在远程医疗会议期间加强治疗联系的策略,和客户对交付方式的偏好应在可能的情况下考虑在内。
    OBJECTIVE: The COVID-19 pandemic required mental health clinicians globally to transition to the delivery of care via telehealth. This study aimed to gain an understanding of clients\' satisfaction with and attitudes towards telehealth mental health services.
    METHODS: Seventy adults who had attended a clinic for mood and anxiety disorders, and participated in at least one telehealth consultation with a psychologist or psychiatrist, completed an anonymous online survey.
    RESULTS: The majority of participants (81.5%) reported satisfaction with telehealth mental health care provided during the COVID-19 pandemic. However, satisfaction overall was significantly higher amongst participants who had received both telehealth and face-to-face mental health care, compared to participants who received care via telehealth only. Advantages of telehealth care reported included convenience and increased access to mental health clinicians. However, disadvantages of telehealth care included greater difficulty developing a rapport with a clinician and expressing oneself via telehealth.
    CONCLUSIONS: Whilst client satisfaction with telehealth mental health care for mood and anxiety disorders is generally high, clinicians should consider the limitations of telehealth from clients\' perspectives. In particular, strategies to enhance therapeutic connection during telehealth sessions may be needed, and client preferences for mode of delivery should be taken into consideration when possible.
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  • 文章类型: Case Reports
    心身医学通过在身体疾病和心理困扰之间提供桥梁,在复杂的医疗病例的管理中发挥着关键作用。本案例研究的重点是一名42岁的沙特女性,被诊断患有乳腺癌和广泛性焦虑症。除了焦虑,病人有强迫性人格特质史,这导致她不愿接受乳房切除术。她不愿与医疗团队互动不足,导致了重大挑战和不遵守治疗。由于这种情况的复杂性,有必要采取包括心理肿瘤干预在内的综合多学科策略。通过专家小组的共同努力解决了沟通问题。建立了全面的患者-从业者理解,这使团队能够说服患者接受手术干预。克服她最初的阻力,患者最终遵守了治疗计划,导致手术成功.使用汉密尔顿焦虑量表进行的术后评估表明焦虑水平显着降低。这个案例强调了心身医学对医疗保健的重要贡献,特别是在需要额外资源分配的具有挑战性的情况下,进一步强调跨学科方法的重要性,高效沟通,以及患者与医生在医疗保健结果方面的融洽关系。
    Psychosomatic medicine has been known to play a pivotal role in the management of complex medical cases by providing a bridge between the physical disease and psychological distress. This case study focuses on a 42-year-old Saudi female diagnosed with breast cancer and generalized anxiety disorder. In addition to anxiety, the patient had a history of obsessive-compulsive personality traits, which contributed to her reluctance to undergo mastectomy. Significant challenges and noncompliance with treatment were caused by her unwillingness and inadequate interaction with the medical team. An integrated multidisciplinary strategy including psycho-oncological interventions was necessary because of the complexity of this case. Communication issues were addressed through the concerted efforts of the specialist teams. A comprehensive patient-practitioner understanding was established, which enabled the teams to persuade the patient to undergo surgical intervention. Overcoming her initial resistance, the patient eventually complied with the treatment plan, leading to a successful surgery. Postsurgical evaluations using the Hamilton Anxiety Scale indicated a significant reduction in anxiety levels. This case underscores the critical contribution of psychosomatic medicine to healthcare, especially in challenging situations that demand additional resource allocation, further highlighting the importance of an interdisciplinary approach, efficient communication, and patient-practitioner rapport in healthcare outcomes.
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  • 文章类型: Case Reports
    该病例报告描述了一名72岁男性的精神病和肿瘤病理学之间复杂的相互作用,该男性被诊断患有低度边缘区B细胞淋巴瘤和严重的精神障碍。包括紧张症.严重精神症状的出现最初掩盖了潜在的淋巴瘤,延迟诊断和复杂的临床管理。值得注意的是,淋巴瘤本身可能导致或加剧了精神疾病,强调肿瘤疾病可能表现为快速进行性痴呆和紧张症。采用了多学科方法,利用电惊厥治疗(ECT)快速解决紧张症,这促进了心理健康的显着改善和肿瘤基础的更清晰的轮廓。同时,患者接受了利妥昔单抗治疗,瞄准淋巴瘤.这个案例强调了对出现精神症状的患者进行全面评估的迫切需要,尤其是老年人,揭示潜在的医疗原因,并说明ECT在管理可能掩盖或使并发医疗问题复杂化的精神疾病方面的功效。
    This case report delineates the intricate interplay between psychiatric and oncological pathology in a 72-year-old male diagnosed with low-grade marginal zone B-cell lymphoma and severe psychiatric disturbances, including catatonia. The presentation of severe psychiatric symptoms initially obscured the underlying lymphoma, delaying diagnosis and complicating clinical management. Notably, the lymphoma itself may have precipitated or exacerbated the psychiatric condition, underscoring the potential for oncological diseases to manifest with rapidly progressive dementia and catatonia. A multidisciplinary approach was employed, utilizing electroconvulsive therapy (ECT) for rapid resolution of catatonia, which facilitated significant mental health improvements and clearer delineation of the oncological underpinnings. Concurrently, the patient was treated with rituximab, targeting the lymphoma. This case highlights the critical need for a comprehensive evaluation in patients presenting with psychiatric symptoms, particularly in the elderly, to uncover potential medical causes and illustrates the efficacy of ECT in managing psychiatric conditions that may overshadow or complicate concurrent medical issues.
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  • 文章类型: Preprint
    早期和准确的诊断对于有效治疗和改善预后至关重要。然而,由于精神病发作的复杂性和个体之间症状的不同表现,识别精神病发作提出了重大挑战。主要困难之一在于精神病的漏报和漏诊,再加上围绕心理健康和个体的耻辱,往往会削弱对他们状况的洞察力。利用电子健康记录(EHR)回顾性识别精神病的现有努力通常依赖于结构化数据,如医疗法规和患者人口统计,往往缺乏必要的信息。应对这些挑战,我们的研究利用自然语言处理(NLP)算法来分析精神病诊断的住院记录,提供基于规则的算法的详细评估,机器学习模型,和预先训练的语言模型。此外,这项研究调查了在训练和评估模型之前使用关键词简化大量笔记数据的有效性。分析了2005年至2019年的4,617份精神科初始入院记录(1,196例精神病病例与3,433例对照),我们发现XGBoost分类器采用术语频率-反向文档频率(TF-IDF)特征,这些特征来自由专家策划的关键词预先选择的笔记,F1得分为0.8881(AUROC[95%CI]:0.9725[0.9717,0.9733])。在同一组注释中,Bluebert表现出相当的功效,F1评分为0.8841(AUROC[95%CI]:0.97[0.9580,0.9820])。两种模型均明显优于传统的基于国际疾病分类(ICD)代码的出院摘要检测方法,F1得分为0.7608,因此将利润率提高了0.12。此外,我们的研究结果表明,关键词预选显著提高了机器学习和预训练语言模型的性能.这项研究说明了NLP技术在入院记录中改善精神病检测的潜力,旨在为将来在EHR记录中应用NLP进行精神病识别的研究提供基础参考。
    Early and accurate diagnosis is crucial for effective treatment and improved outcomes, yet identifying psychotic episodes presents significant challenges due to its complex nature and the varied presentation of symptoms among individuals. One of the primary difficulties lies in the underreporting and underdiagnosis of psychosis, compounded by the stigma surrounding mental health and the individuals\' often diminished insight into their condition. Existing efforts leveraging Electronic Health Records (EHRs) to retrospectively identify psychosis typically rely on structured data, such as medical codes and patient demographics, which frequently lack essential information. Addressing these challenges, our study leverages Natural Language Processing (NLP) algorithms to analyze psychiatric admission notes for the diagnosis of psychosis, providing a detailed evaluation of rule-based algorithms, machine learning models, and pre-trained language models. Additionally, the study investigates the effectiveness of employing keywords to streamline extensive note data before training and evaluating the models. Analyzing 4,617 initial psychiatric admission notes (1,196 cases of psychosis versus 3,433 controls) from 2005 to 2019, we discovered that the XGBoost classifier employing Term Frequency-Inverse Document Frequency (TF-IDF) features derived from notes pre-selected by expert-curated keywords, attained the highest performance with an F1 score of 0.8881 (AUROC [95% CI]: 0.9725 [0.9717, 0.9733]). BlueBERT demonstrated comparable efficacy an F1 score of 0.8841 (AUROC [95% CI]: 0.97 [0.9580,0.9820]) on the same set of notes. Both models markedly outperformed traditional International Classification of Diseases (ICD) code-based detection methods from discharge summaries, which had an F1 score of 0.7608, thus improving the margin by 0.12. Furthermore, our findings indicate that keyword pre-selection markedly enhances the performance of both machine learning and pre-trained language models. This study illustrates the potential of NLP techniques to improve psychosis detection within admission notes and aims to serve as a foundational reference for future research on applying NLP for psychosis identification in EHR notes.
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  • 文章类型: Preprint
    早期和准确的诊断对于有效治疗和改善预后至关重要。然而,由于精神病发作的复杂性和个体之间症状的不同表现,识别精神病发作提出了重大挑战。主要困难之一在于精神病的漏报和漏诊,再加上围绕心理健康和个体的耻辱,往往会削弱对他们状况的洞察力。利用电子健康记录(EHR)回顾性识别精神病的现有努力通常依赖于结构化数据,如医疗法规和患者人口统计,往往缺乏必要的信息。应对这些挑战,我们的研究利用自然语言处理(NLP)算法来分析精神病诊断的住院记录,提供基于规则的算法的详细评估,机器学习模型,和预先训练的语言模型。此外,这项研究调查了在训练和评估模型之前使用关键词简化大量笔记数据的有效性。分析了2005年至2019年的4,617份精神科初始入院记录(1,196例精神病病例与3,433例对照),我们发现XGBoost分类器采用术语频率-反向文档频率(TF-IDF)特征,这些特征来自由专家策划的关键词预先选择的笔记,F1得分为0.8881(AUROC[95%CI]:0.9725[0.9717,0.9733])。在同一组注释中,Bluebert表现出相当的功效,F1评分为0.8841(AUROC[95%CI]:0.97[0.9580,0.9820])。两种模型均明显优于传统的基于国际疾病分类(ICD)代码的出院摘要检测方法,F1得分为0.7608,因此将利润率提高了0.12。此外,我们的研究结果表明,关键词预选显著提高了机器学习和预训练语言模型的性能.这项研究说明了NLP技术在入院记录中改善精神病检测的潜力,旨在为将来在EHR记录中应用NLP进行精神病识别的研究提供基础参考。
    Early and accurate diagnosis is crucial for effective treatment and improved outcomes, yet identifying psychotic episodes presents significant challenges due to its complex nature and the varied presentation of symptoms among individuals. One of the primary difficulties lies in the underreporting and underdiagnosis of psychosis, compounded by the stigma surrounding mental health and the individuals\' often diminished insight into their condition. Existing efforts leveraging Electronic Health Records (EHRs) to retrospectively identify psychosis typically rely on structured data, such as medical codes and patient demographics, which frequently lack essential information. Addressing these challenges, our study leverages Natural Language Processing (NLP) algorithms to analyze psychiatric admission notes for the diagnosis of psychosis, providing a detailed evaluation of rule-based algorithms, machine learning models, and pre-trained language models. Additionally, the study investigates the effectiveness of employing keywords to streamline extensive note data before training and evaluating the models. Analyzing 4,617 initial psychiatric admission notes (1,196 cases of psychosis versus 3,433 controls) from 2005 to 2019, we discovered that the XGBoost classifier employing Term Frequency-Inverse Document Frequency (TF-IDF) features derived from notes pre-selected by expert-curated keywords, attained the highest performance with an F1 score of 0.8881 (AUROC [95% CI]: 0.9725 [0.9717, 0.9733]). BlueBERT demonstrated comparable efficacy an F1 score of 0.8841 (AUROC [95% CI]: 0.97 [0.9580, 0.9820]) on the same set of notes. Both models markedly outperformed traditional International Classification of Diseases (ICD) code-based detection methods from discharge summaries, which had an F1 score of 0.7608, thus improving the margin by 0.12. Furthermore, our findings indicate that keyword pre-selection markedly enhances the performance of both machine learning and pre-trained language models. This study illustrates the potential of NLP techniques to improve psychosis detection within admission notes and aims to serve as a foundational reference for future research on applying NLP for psychosis identification in EHR notes.
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  • 文章类型: Journal Article
    精神科的前线工作人员需要以非常高的专业水平执行,以确保患者和社区安全。与此同时,他们面临着高水平的压力和工作场所的创伤。这可能会对他们的职业生活质量产生严重后果。此外,卫生保健工作者总体上比一般人群有更高的儿童逆境发生率。CRITIC(护理者的标准事件和侵略)研究旨在提高对个人生活史(童年逆境和仁慈)之间相互作用的理解,个人能力,暴露于工作中的创伤和暴力以及职业生活质量(ProQOL)。
    评论家研究是对前线这些方面的横断面调查,临床和法医精神病学的治疗和管理人员。我们的目标是包括360名参与者。参与者将被要求完成关于童年逆境和童年仁慈的问卷(评估个人生活史),职业生活质量,目前的创伤和暴力暴露,当前的心理健康(抑郁症,焦虑和压力),应对,社会支持,工作参与度和韧性。在这项研究中,我们将研究不良和仁慈的童年经历在工作场所创伤暴露与职业生活质量之间的关系中的调节作用。最后,关于创伤之间关系的理论模型,将使用结构方程模型测试专业功能背景下的压力和应对。
    批评研究考察了哪些因素影响童年逆境和仁慈之间的复杂关系,和医护人员的ProQOL。它还旨在深入了解个人生活史之间的复杂关系,个体特征,在工作和ProQOL中暴露于创伤和暴力。该结果可用于设计干预措施,以增加对创伤的抵抗力,并改善医疗保健专业人员的专业生活质量。
    CRITIC研究已获得伊拉斯谟医学中心医学伦理委员会的批准,试验注册号为NL73417.078.20。
    UNASSIGNED: Frontline staff in psychiatry need to perform at a very high professional level in order to ensure patient and community safety. At the same time they are exposed to high levels of stress and workplace trauma. This may have severe consequences for their professional quality of life. In addition, health care workers in general have higher incidence levels of childhood adversity than the general population. The CRITIC (CRITical Incidents and aggression in Caregivers) Study aims to improve increased understanding of the interaction between personal life history (childhood adversity and benevolence), individual capabilities, exposure to trauma and violence at work and Professional Quality of Life (ProQOL).
    UNASSIGNED: The Critic Study is a cross-sectional survey of these aspects in frontline, treatment and administrative staff in clinical and forensic psychiatry. We aim to include 360 participants. Participants will be asked to complete questionnaires on childhood adversity and childhood benevolence (assessing personal life history), professional quality of life, current trauma and violence exposure, current mental health (depression, anxiety and stress), coping, social support, work engagement and resilience. In this study we will examine the moderating role of adverse and benevolent childhood experiences in the association between workplace trauma exposure and professional quality of life. Finally, a theoretical model on the relationships between trauma, stress and coping in the context of professional functioning will be tested using structural equation modelling.
    UNASSIGNED: The CRITIC study examines which factors influence the complex relationship between childhood adversity and benevolence, and ProQOL in healthcare workers. It also aims to provide insight into the complex relationship between personal life history, individual characteristics, exposure to trauma and violence at work and ProQOL. The results can be used for designing interventions to increase resilience to trauma and to improve professional quality of life among health care professionals.
    UNASSIGNED: The CRITIC study has been approved by the Medical Ethical Committee of the Erasmus Medical Centre, under trial registration number NL73417.078.20.
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  • 文章类型: Case Reports
    幻听是患者认为来自身体外部的声音。虽然引起幻听的机制还不完全清楚,有大量证据表明,幻听会对参与听觉处理的相同区域的大脑产生持久影响。突发性感觉神经性听力损失(SSNHL)是一种鲜为人知的疾病,患者通常在生命的第五个十年中失去听力。在这里,我们介绍了一例42岁的女性,该女性有精神分裂症伴幻听病史,在40岁时经历了SSNHL。由于患者没有已知的SSNHL危险因素,我们认为该患者的SSNHL与她的幻听史有关.通过这个案例的介绍,我们希望探讨幻听的发病机制,并研究幻听与SSNHL之间潜在的双向关联.这项研究要求进一步调查幻听对大脑的影响,SSNHL的可能病因,以及幻听可能是SSNHL的危险因素。
    Auditory hallucinations are sounds that patients perceive as coming from outside of their body. Though the mechanism causing auditory hallucinations is not entirely understood, there is a significant amount of evidence suggesting that auditory hallucinations leave lasting impacts on the brain in the same regions that are involved in auditory processing. Sudden sensorineural hearing loss (SSNHL) is a poorly understood condition in which patients lose their hearing typically in the fifth decade of life. Here we present a case of a 42-year-old female with a history of schizophrenia with auditory hallucinations who experienced SSNHL at age 40. As the patient had no known risk factors for SSNHL, we propose that this patient\'s SSNHL is linked to her history of auditory hallucinations. Through the presentation of this case, we hope to explore the pathogenesis of auditory hallucinations and investigate a potentially bidirectional association between auditory hallucinations and SSNHL. This study calls for further investigation into the impacts of auditory hallucinations on the brain, possible etiologies of SSNHL, and the possibility that auditory hallucinations serve as a risk factor for SSNHL.
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  • 文章类型: Journal Article
    In the wake of the COVID-19 pandemic, healthcare systems rapidly embraced technology as a means of providing care while adhering to social distancing protocols. In this brief article, we report on a new telehealth initiative recently implemented in an out-patient psychiatric setting and outline the novel role telehealth may serve in facilitating psychiatric care globally. The uptake of telehealth represents a new and exciting opportunity to increase both access to, and quality of, care for people with mental illness.
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  • 文章类型: Journal Article
    鉴于临床医生和研究人员在处理神经精神疾病方面面临的持续困难,越来越明显的是,有必要超越传统的学科界限。这项研究巩固了现有的材料,审视历史的变化,基本的神经生物学方面,以及神经病学和精神病学之间共有的临床表现。本调查考察了神经精神病学的历史发展,关注早期对精神疾病的理解与后来的神经病学和精神病学的划分之间的关系。重点是在理解共同的神经生物学途径和遗传因素方面的最新进展,这些因素突出了这些领域的合并。该研究通过分析重叠的认知,突出了神经精神疾病临床表现的复杂性,情感,和行为症状。文本批评了传统框架中的诊断问题,强调区分神经学和精神病学起源的局限性。这对实现正确的诊断和安排适当的治疗有影响。本文探讨了发展多学科护理方法,强调神经学家和精神科医生之间的成功合作。这项研究考察了执行计划的困难以及确定将不同要素结合起来的障碍的过程。它还强调迫切需要改进教学和学习,以便顺利合作。本文通过研究以共享途径为重点的药理疗法来研究治疗意义。它还讨论了管理一起发生的神经和精神疾病所涉及的困难。该研究还探讨了非药物疗法,如心理治疗和康复方法,作为综合治疗方法的一部分。预测未来,该报告确定了可以改进研究的领域,并预测了技术改进对该主题的影响。提出了鼓励进一步探索的建议,合作,独创性缩小了神经病学和精神病学之间的鸿沟,最终增强我们对神经精神疾病的理解和治疗。这种实时综合增加了正在进行的讨论,提供有价值的见解,与当代神经精神病学研究和治疗的不断变化的领域保持一致。
    Given the ongoing difficulties faced by clinicians and researchers in dealing with neuropsychiatric illnesses, it is becoming more and more evident that there is a need to go beyond traditional disciplinary boundaries. This research consolidates existing material, examining changes in history, the fundamental neurobiological aspects, and the shared clinical manifestations between neurology and psychiatry. This inquiry examines the historical development of neuropsychiatry, focusing on the relationship between early understandings of mental illness and the later division of neurology and psychiatry. The focus is on recent advancements in comprehending the common neurobiological pathways and genetic factors that highlight the merging of these fields. The research highlights the complexities of clinical presentations in neuropsychiatric illnesses by analyzing the overlapping cognitive, affective, and behavioral symptoms. The text critiques the diagnostic issues in traditional frameworks, emphasizing the limitations in differentiating between neurological and psychiatric origins. This has ramifications for achieving correct diagnosis and arranging appropriate treatment. The paper explores developing multidisciplinary care approaches, highlighting successful collaborations between neurologists and psychiatrists. This study examines the difficulties in carrying out a plan and the process of identifying obstacles to combining different elements. It also highlights the urgent need for improved instruction and learning for smooth cooperation. The paper examines the therapeutic implications by investigating pharmacological therapies focusing on shared pathways. It also discusses the difficulties involved in managing neurological and psychiatric diseases that occur together. The study also explores non-pharmacological therapies, such as psychotherapy and rehabilitation methods, as part of a comprehensive treatment approach. Anticipating the future, the report identifies areas where the study could be improved and forecasts the influence of technological improvements on the subject. Suggestions are put out to encourage additional exploration, cooperation, and originality to narrow the divide between neurology and psychiatry, ultimately augmenting our comprehension and treatment of neuropsychiatric illnesses. This real-time synthesis adds to the ongoing discussion, providing valuable insights that align with the ever-changing field of contemporary neuropsychiatric research and therapy.
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  • 文章类型: Journal Article
    目的本研究的目的是研究重度抑郁症(MDD)与广泛性焦虑症(GAD)相比,自我报告的疲劳症状严重程度的变异性。方法采用抑郁和焦虑问卷对100例疲劳患者进行回顾性分析。该研究检查了疲劳的评级是否根据患者在MDD与当同一患者在GAD的背景下评估疲劳时。使用相关样本Wilcoxon符号秩检验和Mann-WhitneyU检验比较抑郁和焦虑疲劳评分之间的中位数差异。使用的显著性水平为0.05。结果本研究发现,无论给药顺序如何,配对的抑郁疲劳和焦虑疲劳评分(抑郁评分-焦虑评分)的中位数差异均具有统计学意义(Wilcoxon符号秩检验统计量=135.500,p值=.008,N=100配对评分)。结论本研究的结论表明,尽管疲劳症状在诊断统计手册5(DSM-5)中列出了MDD和GAD的标准,根据综合征的背景,患者可能会有不同的感觉。这强调了考虑MDD和GAD患者症状报告背景以改进诊断方法和治疗策略的重要性。
    Objective The objective of this study is to examine the variability in the self-reported fatigue symptom severity in major depressive disorder (MDD) compared to generalized anxiety disorder (GAD). Methods A retrospective chart review was conducted of 100 patients evaluated for fatigue using depression and anxiety questionnaires. The study examined whether ratings of fatigue varied based on whether fatigue was being rated by the patient in the context of MDD vs. when fatigue was being rated by the same patient in the context of GAD. A related-sample Wilcoxon signed-rank test and Mann-Whitney U test were used to compare the median differences between depression and anxiety fatigue scores. The significance level used was 0.05. Results This study found a statistically significant difference in the median difference of the paired depression fatigue and anxiety fatigue scores (depression score - anxiety score) regardless of the order of administration (Wilcoxon signed-rank test statistic = 135.500, p-value =.008, N = 100 paired scores). Conclusion The study\'s conclusions show that although the symptom of fatigue is listed in the Diagnostic Statistical Manual 5 (DSM-5) criteria for MDD as well as GAD, it may be perceived by patients differently based on the context of the syndrome. This emphasizes the importance of considering the context of symptom reporting in patients with MDD and GAD to improve diagnostic methodologies and treatment strategies.
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