PDF(Pubmed)
Abstract：
This case report delineates the intricate interplay between psychiatric and oncological pathology in a 72-year-old male diagnosed with low-grade marginal zone B-cell lymphoma and severe psychiatric disturbances, including catatonia. The presentation of severe psychiatric symptoms initially obscured the underlying lymphoma, delaying diagnosis and complicating clinical management. Notably, the lymphoma itself may have precipitated or exacerbated the psychiatric condition, underscoring the potential for oncological diseases to manifest with rapidly progressive dementia and catatonia. A multidisciplinary approach was employed, utilizing electroconvulsive therapy (ECT) for rapid resolution of catatonia, which facilitated significant mental health improvements and clearer delineation of the oncological underpinnings. Concurrently, the patient was treated with rituximab, targeting the lymphoma. This case highlights the critical need for a comprehensive evaluation in patients presenting with psychiatric symptoms, particularly in the elderly, to uncover potential medical causes and illustrates the efficacy of ECT in managing psychiatric conditions that may overshadow or complicate concurrent medical issues.
摘要：
该病例报告描述了一名72岁男性的精神病和肿瘤病理学之间复杂的相互作用，该男性被诊断患有低度边缘区B细胞淋巴瘤和严重的精神障碍。包括紧张症.严重精神症状的出现最初掩盖了潜在的淋巴瘤，延迟诊断和复杂的临床管理。值得注意的是,淋巴瘤本身可能导致或加剧了精神疾病，强调肿瘤疾病可能表现为快速进行性痴呆和紧张症。采用了多学科方法，利用电惊厥治疗（ECT）快速解决紧张症，这促进了心理健康的显着改善和肿瘤基础的更清晰的轮廓。同时,患者接受了利妥昔单抗治疗,瞄准淋巴瘤.这个案例强调了对出现精神症状的患者进行全面评估的迫切需要，尤其是老年人，揭示潜在的医疗原因，并说明ECT在管理可能掩盖或使并发医疗问题复杂化的精神疾病方面的功效。
