背景:虽然儿童肥胖很重要,很少研究牙槽裂患儿二次牙槽骨植骨(ABG)后移植组织中体重指数(BMI)与骨密度(BMD)进展之间的关系.因此,本研究探讨了BMI对ABG术后BMD进展的影响。
方法:总共,纳入39例牙列混合期接受ABG治疗的牙槽裂患者。患者被归类为体重不足,正常体重,根据年龄和性别调整后的BMI,或超重或肥胖。通过术后6个月(T1)和2年(T2)的锥形束计算机断层扫描扫描,以Hounsfield单位(HU)测量BMD。调整后的BMD(HUraced组织/HUpogonion,BMDa)用于进一步分析。
结果:对于体重不足,正常体重,超重或肥胖患者,BMDaT1值为72.87%,91.85%,92.89%,分别(p=0.727);BMDaT2值为111.49%,112.57%,和113.10%(p=0.828);密度增强率为29.24%,24.61%,和22.14%(p=0.936)。BMI与BMDaT1,BMDaT2或密度增强率之间没有显着相关性(分别为p=0.223,0.156和0.972)。对于BMI<17和≥17kg/m2的患者,BMDaT1值分别为89.80%和92.89%,分别为(p=0.496);BMDaT2值分别为111.49%和113.10%(p=0.216);密度增强率分别为23.06%和26.39%(p=0.573)。
结论:不同BMI值的患者在我们的ABG手术后2年的随访中具有相似的结果(BMDaT1,BMDaT2或密度增强率)。
Although childhood obesity matters, the association between body mass index (BMI) and bone mineral density (BMD) progression in grafted tissue after secondary alveolar bone grafting (ABG) for children with cleft alveolus is scarcely studied. Accordingly, this study explored the influence of BMI on BMD progression after ABG.
In total, 39 patients with cleft alveolus receiving ABG at the mixed dentition stage were enrolled. Patients were classified as underweight, normal weight, or overweight or obese according to age- and sex-adjusted BMI. BMD was measured in Hounsfield units (HU) from cone-beam computed tomography scans obtained 6 months (T1) and 2 years (T2) postoperatively. Adjusted BMD (HUgrafted tissue/HUpogonion, BMDa) was used for further analysis.
For underweight, normal-weight, and overweight or obese patients, BMDaT1 values were 72.87%, 91.85%, and 92.89%, respectively (p = 0.727); BMDaT2 values were 111.49%, 112.57%, and 113.10% (p = 0.828); and density enhancement rates were 29.24%, 24.61%, and 22.14% (p = 0.936). No significant correlation was observed between BMI and BMDaT1, BMDaT2, or density enhancement rates (p = 0.223, 0.156, and 0.972, respectively). For patients with BMI < 17 and ≥ 17 kg/m2, BMDaT1 values were 89.80% and 92.89%, respectively (p = 0.496); BMDaT2 values were 111.49% and 113.10% (p = 0.216); and density enhancement rates were 23.06% and 26.39% (p = 0.573).
Patients with different BMI values had similar outcomes (BMDaT1, BMDaT2, or density enhancement rate) after our ABG procedure in the 2-year postoperative follow-up.