■退行性脊髓型颈椎病(DCM)是一种衰弱的疾病,其特征是颈脊髓受压,导致神经功能缺损.这项研究旨在探讨糖尿病(DM)和肥胖等合并症与DCM患者术前生活质量(QOL)之间的关系。并检查疼痛和麻木的分布。
■对86例术前DCM患者进行了横断面研究。患者报告的结果指标(PROM),包括颈部的核心结果指标(COMI-Neck),颈部残疾指数(NDI)EQ-5D-3L,SF-12v2评估QOL,并收集基线特征。患者按糖尿病和肥胖状态分类,导致17和69没有DM,和27肥胖,59例非肥胖患者。在统计分析中,我们比较了PROM和基线特征,
■该研究发现,有和没有糖尿病或肥胖的患者的术前生活质量没有显著差异。此外,MANCOVA的结果表明,DM和肥胖都不是单独的,也不是他们的组合,与PROM的总分有关联。在每组中,COMI颈部的症状特异性健康评分明显较高,暗示令人痛苦的当前症状(中位数:10)。在NDI上,疼痛强度的中位数评分,提升,工作,娱乐子项目为3。疼痛主要报告在颈部和下背部,而麻木在上肢和下肢的外围区域更为普遍。
■术前生活质量不受DM和/或肥胖的影响。DCM相关症状可能掩盖了与这些合并症的关联。不管术前情况如何,重要的是要解决手术前带来挑战的PROM项目.
UNASSIGNED: Degenerative cervical myelopathy (DCM) is a debilitating condition characterized by compression of the cervical spinal cord, leading to neurological deficits. This study aimed to investigate the association between comorbidities like diabetes mellitus (DM) and obesity and quality of life (QOL) in preoperative patients with DCM, and to examine the distribution of pain and numbness.
UNASSIGNED: A cross-sectional study with 86 preoperative patients with DCM was conducted. Patient-reported outcome measures (PROMs) including Core Outcome Measure Index for the neck (COMI-Neck), Neck Disability Index (NDI), EQ-5D-3L, SF-12v2 assessed QOL, and baseline characteristics were collected. Patients were categorized by diabetic and obesity status, resulting in 17 with and 69 without DM, and 27 obese, 59 nonobese patients. In the statistical analysis, we compared PROMs and baseline characteristics, and conducted MANCOVA to investigate the association of DM and obesity with PROMs.
UNASSIGNED: The study found no significant differences in preoperative QOL between patients with and without DM or obesity. Additionally, the results of MANCOVA indicated that neither DM nor obesity alone, nor their combination, had an association with the total scores of PROMs. In each group, the Symptom-specific well-being score on the COMI-Neck was notably high, implying distressing current symptoms (median: 10). On the NDI, the median score for pain intensity, lifting, work, and recreation subitems was 3. Pain was predominantly reported in the neck and lower back, while numbness was more prevalent in the peripheral regions of the upper and lower limbs.
UNASSIGNED: Preoperative QOL was not significantly affected by the presence of DM and/or obesity. DCM-related symptoms may mask the associations with these comorbidities. Regardless of the preoperative condition, it is important to address the PROMs items that posed challenges before surgery.