Abstract:
The primary aim of this study is to assess the viability of employing multimodal radiomics techniques for distinguishing between cervical spinal cord injury and spinal cord concussion in cervical magnetic resonance imaging. This is a multicenter study involving 288 patients from a major medical center as the training group, and 75 patients from two other medical centers as the testing group. Data regarding the presence of spinal cord injury symptoms and their recovery status within 72 h were documented. These patients underwent sagittal T1-weighted and T2-weighted imaging using cervical magnetic resonance imaging. Radiomics techniques are used to help diagnose whether these patients have cervical spinal cord injury or spinal cord concussion. 1197 radiomics features were extracted for each modality of each patient. The accuracy of T1 modal in testing group is 0.773, AUC is 0.799. The accuracy of T2 modal in testing group is 0.707, AUC is 0.813. The accuracy of T1 + T2 modal in testing group is 0.800, AUC is 0.840. Our research indicates that multimodal radiomics techniques utilizing cervical magnetic resonance imaging can effectively diagnose the presence of cervical spinal cord injury or spinal cord concussion.
摘要:
这项研究的主要目的是评估在颈椎磁共振成像中采用多模式影像组学技术区分颈脊髓损伤和脊髓脑震荡的可行性。这是一项多中心研究,涉及来自主要医疗中心的288名患者作为培训小组,以及来自另外两个医疗中心的75名患者作为测试组。记录了有关脊髓损伤症状的存在及其在72小时内的恢复状态的数据。这些患者使用颈部磁共振成像进行矢状T1加权和T2加权成像。影像组学技术用于帮助诊断这些患者是否患有颈脊髓损伤或脊髓脑震荡。为每个患者的每个模式提取1197个影像组学特征。测试组T1模态的准确度为0.773,AUC为0.799。测试组T2模态的准确度为0.707,AUC为0.813。试验组T1+T2模态的准确度为0.800,AUC为0.840。我们的研究表明,利用颈椎磁共振成像的多模式影像组学技术可以有效地诊断颈髓损伤或脊髓脑震荡的存在。