浸润性宫颈癌的主要危险因素是高危型人乳头瘤病毒(HPV)的持续感染。HPV是最普遍的性传播感染(STI),与15种不同的癌症有关。宫颈癌是女性中最常见的癌症之一,特别是在资源有限的国家。宫颈癌是一种HPV疾病,在资源有限的国家中,全球负担最高。随着医疗保健的改善和全国范围的筛查计划,在过去的40年中,宫颈癌的死亡率有所下降。许多发展中国家已被证明缺乏知识和寻求健康的做法,制定适当的意识和免疫计划是必要的。降低宫颈癌发病率的最佳策略是通过给予HPV疫苗以及常规宫颈筛查。HPV疫苗对公众健康至关重要。针对所有HPV亚型的疫苗接种,即,二价,四价,和非共价的,是可用的。财务问题是HPV疫苗接种的主要障碍。疫苗接种的行为和社会驱动因素框架,其中包括实际问题,动机,社会进程,思想,和感情,广泛用于发现与HPV疫苗接种相关的重要方面。本文综述了HPV对宫颈癌的负担以及HPV疫苗接种的优势。
The main risk factor for invasive cervical carcinoma is persistent infection by the high-risk human papillomavirus (HPV). HPV is the most prevalent sexually transmitted infection (STI) and has been linked to 15 different cancers. Cervical cancer is one of the most frequent cancers among women, particularly in resource-limited countries. Cervical cancer is an HPV disease with the highest worldwide burden in resource-limited nations. With improved medical care and nationwide screening programmes, the mortality rate from cervical cancer has decreased in the past 40 years. Many developing nations have been shown to have inadequate knowledge and health-seeking practices, making proper awareness and immunisation programmes necessary. The best strategy to reduce the incidence of cervical cancer is through the administration of HPV vaccines along with routine cervical screening. The HPV vaccine is crucial for public health. Vaccinations against all HPV subtypes, namely, bivalent, quadrivalent, and nonavalent, are available. Financial issues are the main barrier to HPV vaccination. The framework for behavioural and social drivers of vaccination, which includes practical concerns, motivation, social processes, thoughts, and feelings, is widely used to uncover important aspects linked with HPV vaccination. The burden of cervical cancer due to HPV and the advantages of HPV vaccination are summarised in this review article.