药物活性化合物(PhAC)代表一类新兴的污染物。有可能对人类健康和生态系统产生负面影响,药物在水生系统中的存在正成为一个令人担忧的问题。抗生素是一类主要的PhACs,从长远来看,它们在废水中的存在意味着健康风险。为了从废水中有效去除抗生素,成本效益高,和大量可用的废物衍生吸附剂的结构。在这项研究中,芒果籽粒(MSK),作为原始生物炭(Py-MSK)和纳米二氧化铈(Ce-Py-MSK)均用于利福平(RIFM)和替加环素(TIGC)的修复。为了节省时间和资源,吸附实验使用基于多变量的方案进行管理,执行分数阶乘设计(FrFD)。两种抗生素的去除百分比(%R)是根据四个变量来开发的:pH,吸附剂用量,初始药物浓度,接触时间。初步实验表明,与Py-MSK相比,Ce-Py-MSK对RIFM和TIGC均具有更高的吸附效率。RIFM的%R为92.36%,而TIGC的%R为90.13%。为了理解吸附过程,两种吸附剂的结构阐明使用FT-IR进行,SEM,TEM,EDX,和XRD分析证实了纳米二氧化铈对吸附剂表面的装饰。BET分析显示,Ce-Py-MSK与Py-MSK(24.72m2/g)相比具有更高的表面积(33.83m2/g)。等温线参数表明Freundlich模型最适合Ce-Py-MSK-药物相互作用。RIFM和TIGC的最大吸附容量(qm)为102.25和49.28mg/g,分别。两种药物的吸附动力学均符合伪二阶(PSO)和Elovich模型。这项研究,因此,已经确立了Ce-Py-MSK作为绿色的适用性,可持续,成本效益高,选择性,和高效吸附剂处理制药废水。
Pharmaceutically active compounds (PhACs) represent an emerging class of contaminants. With a potential to negatively impact human health and the ecosystem, existence of pharmaceuticals in the aquatic systems is becoming a worrying concern. Antibiotics is a major class of PhACs and their existence in wastewater signifies a health risk on the long run. With the purpose of competently removing antibiotics from wastewater, cost-effective, and copiously available waste-derived adsorbents were structured. In this study, mango seeds kernel (MSK), both as a pristine biochar (Py-MSK) and as a nano-ceria-laden (Ce-Py-MSK) were applied for the remediation of rifampicin (RIFM) and tigecycline (TIGC). To save time and resources, adsorption experiments were managed using a multivariate-based scheme executing the fractional factorial design (FrFD). Percentage removal (%R) of both antibiotics was exploited in terms of four variables: pH, adsorbent dosage, initial drug concentration, and contact time. Preliminary experiments showed that Ce-Py-MSK has higher adsorption efficiency for both RIFM and TIGC compared to Py-MSK. The %R was 92.36% for RIFM compared to 90.13% for TIGC. With the purpose of comprehending the adsorption process, structural elucidation of both sorbents was performed using FT-IR, SEM, TEM, EDX, and XRD analyses which confirmed the decoration of the adsorbent surface with the nano-ceria. BET analysis revealed that Ce-Py-MSK has a higher surface area (33.83 m2/g) contrasted to the Py-MSK (24.72 m2/g). Isotherm parameters revealed that Freundlich model best fit Ce-Py-MSK-drug interactions. A maximum adsorption capacity (qm) of 102.25 and 49.28 mg/g was attained for RIFM and TIGC, respectively. Adsorption kinetics for both drugs conformed well with both pseudo-second order (PSO) and Elovich models. This study, therefore, has established the suitability of Ce-Py-MSK as a green, sustainable, cost-effective, selective, and efficient adsorbent for the treatment of pharmaceutical wastewater.