背景:从儿童时期开始的复发性关节积血导致进行性关节退化。血友病患者有慢性疼痛,功能性残疾和对健康相关生活质量的感知降低。
目的:分析成人血友病性关节病患者的生活质量及其与疼痛的关系。接头条件,运动恐惧症和灾难论。
方法:83例成人血友病患者纳入本多中心,横截面,描述性研究。感知生活质量(36项简短形式健康调查),感知到的通常和最大疼痛(视觉模拟量表),关节状况(血友病联合健康评分),评估运动恐惧症(运动恐惧症的坦帕量表)和灾难性(疼痛灾害性量表)。社会人口统计学,收集临床和治疗变量以及疼痛控制的药物消耗.描述性统计使用平均值和标准偏差。采用Pearson相关检验计算生活质量与因变量的相关性。对于独立样本,使用Student'st检验计算作为二项变量的函数的生活质量差异。
结果:血友病患者所感知的生活质量的身体成分低于西班牙人群(30.51VS48.85)。关于心理成分,血友病患者表现出较高的值(56.07VS49.97).突变与生活质量问卷的所有项目相关(p<.05)。除角色-情绪外,运动恐惧症与所有生活质量相关(p<.05)(r=-.18;p>.05)。习惯性和最大关节疼痛与所有项目相关,除了角色情绪(分别为r=-.19和r=-.09)和心理成分评分(分别为r=-.16和r=-.07)。灾难性和每周药物摄入量与生活质量呈负相关。年龄与感知的生活质量呈正相关。根据血友病的严重程度和疼痛控制药物的摄入量,生活质量存在差异。
结论:成人血友病患者的生活质量比西班牙人群差。疼痛,运动恐惧症,灾难主义,血友病的严重程度和疼痛控制药物的摄入会影响这些患者的生活质量.
BACKGROUND: Recurrent hemarthrosis that begin in childhood lead to progressive joint deterioration. Patients with haemophilia have chronic pain, functional disability and a reduced perception of health-related quality of life.
OBJECTIVE: To analyse the perceived quality of life of adult patients with haemophilic arthropathy and its relationship with pain, joint condition, kinesiophobia and
catastrophism.
METHODS: Eighty-three adult patients with haemophilia were included in this multicentre, cross-sectional, descriptive study. Perceived quality of life (36-Item Short Form Health Survey), perceived usual and maximum pain (visual analogue scale), joint condition (Haemophilia Joint Health Score), kinesiophobia (Tampa Scale of Kinesiophobia) and
catastrophism (Pain Catastrophizing Scale) were assessed. Sociodemographic, clinical and therapeutic variables and drug consumption for pain control were collected. Descriptive statistics used means and standard deviations. The correlation of quality of life with the dependent variables was calculated with the Pearson correlation test. The differences in quality of life as a function of the binomial variables were calculated with Student\'s t-test for independent samples.
RESULTS: Physical component of quality of life perceived by patients with hemophilia is lower than Spanish population (30.51 VS 48.85). Regarding the mental component, patients with hemophilia showed higher values (56.07 VS 49.97).
Catastrophism correlated (p < .05) with all items of quality of life questionnaire. Kinesiophobia correlated (p < .05) with all items of quality of life except to role-emotional (r = -.18; p > .05). Habitual and maximal joint pain correlated with all items except to role-emotional (r = - .19 and r = - .09, respectively) and mental component score (r = - .16 and r = - .07, respectively).
Catastrophism and weekly drug intake were inversely correlated with quality of life. Age was positively correlated with perceived quality of life. There were differences in quality of life as a function of the severity of haemophilia and the intake of drugs for pain control.
CONCLUSIONS: The perceived quality of life of adult patients with haemophilia is worse than that of the Spanish population. Pain, kinesiophobia,
catastrophism, haemophilia severity and the intake of pain-control medication influence the quality of life of these patients.