PDF(Pubmed)
Abstract：
Fibromyalgia (FM) is a chronic pain syndrome hypothesized to arise from a state of neurogenic inflammation. Mechanisms responsible for pain, as well as psychological variables, are typically altered in this condition. The main objective of this research was to explore somatosensory and psychological alterations in women with FM. The secondary objective was to carry out a secondary analysis to correlate the different variables studied and delve into the influences between them. The relationship between different psychological variables in fibromyalgia is not clear in the previous scientific literature. Forty-four individuals participated, of which twenty-two were controls and twenty-two were women with fibromyalgia. The main outcome measures were the Numeric Pain Rating Scale, Fibromyalgia Impact Questionnaire, pressure pain threshold, conditioned pain modulation, anxiety and depression symptoms, catastrophizing and kinesiophobia cognitions. The main analysis showed that there is a moderate correlation between the psychological variables of depression and fear of movement and the ability to modulate pain. There is also a moderately inverse correlation between pain catastrophizing cognitions and pain intensity/disability. Multiple moderate and strong correlations were found among the various psychological variables studied. FM patients exhibit somatosensory alterations alongside negative psychological symptoms that influence the experience of pain, and they may perpetuate the state of neurogenic inflammation.
摘要：
纤维肌痛（FM）是一种慢性疼痛综合征，假设是由神经源性炎症状态引起的。负责疼痛的机制，以及心理变量，在这种情况下通常会发生变化。这项研究的主要目的是探索FM女性的体感和心理改变。次要目标是进行次要分析，以关联研究的不同变量，并深入研究它们之间的影响。纤维肌痛中不同心理变量之间的关系在以前的科学文献中并不清楚。44个人参加，其中22人是对照组，22人是患有纤维肌痛的女性。主要结果指标是数字疼痛评定量表，纤维肌痛影响问卷，压力痛阈值，条件性疼痛调制，焦虑和抑郁症状,灾难化和运动恐惧症认知。主要分析表明，抑郁和对运动的恐惧的心理变量与调节疼痛的能力之间存在中等相关性。疼痛灾难化认知与疼痛强度/残疾之间也存在中度负相关。在研究的各种心理变量中发现了多个中度和强相关性。FM患者表现出躯体感觉改变以及影响疼痛体验的负面心理症状，它们可能会延续神经源性炎症的状态。
