如今,创伤引起的骨疾病和骨缺损的患病率越来越高,癌症,感染,变性和炎症。修复因外伤而丢失的骨组织,骨折,或由局部侵入性病理导致的手术切除需要骨再生。作为传统治疗的替代方法,基于天然产品的可持续材料,如蜜蜂衍生产品(蜂蜜,蜂胶,蜂王浆,蜂花粉,蜂蜡,和蜂毒),可以考虑。蜜蜂衍生产品,尤其是蜂蜜,长期以来,他们的治疗特性得到了认可。有一种植物化学物质的混合物,通过它们的抗菌作用提供骨骼保护,抗氧化剂,和抗炎特性。这篇综述旨在总结目前有关蜜蜂衍生产品对骨再生影响的证据。总之,蜂蜜,蜂胶,蜂王浆,蜂蜡,和蜂毒可以作为促进骨骼健康的天然产品。
Nowadays, there is an increasing prevalence of bone diseases and defects caused by trauma, cancers, infections, and degenerative and inflammatory conditions. The restoration of bone tissue lost due to trauma, fractures, or surgical removal resulting from locally invasive pathologies requires bone regeneration. As an alternative to conventional treatments, sustainable materials based on natural products, such as honeybee-derived products (honey, propolis, royal jelly, bee pollen, beeswax, and bee venom), could be considered. Honeybee-derived products, particularly honey, have long been recognized for their healing properties. There are a mixture of phytochemicals that offer bone protection through their antimicrobial, antioxidant, and anti-inflammatory properties. This review aims to summarize the current evidence regarding the effects of honeybee-derived products on bone regeneration. In conclusion, honey, propolis, royal jelly, beeswax, and bee venom can potentially serve as natural products for promoting bone health.