目的:这项工作旨在评估睡眠持续时间与心脏代谢风险(肥胖,血压,脂质,白蛋白尿和A1C),并调查生活方式因素(身体活动,曝光,咖啡因的消耗和糖的消耗)与儿童的睡眠时间有关。
方法:这项横断面研究纳入了2011年至2014年在NHANES注册的3907名6-17岁儿童的全国代表性样本。睡眠持续时间定义为通过身体活动监测器(PAM)测量的超过7天的每日平均睡眠时间。无有效睡眠数据≥95%的研究参与者被排除在外。回归模型根据年龄进行了调整,性别,种族,体重指数(BMI)Z评分,身体活动和光照。
结果:在调整后的回归模型中,较长的睡眠时间与较低的收缩压指数(β=-3.63*10-5,95%CI-6.99*10-5,-2.78*10-6,p=0.035)和BMIZ评分(β=-0.001,95%CI-0.001,0.000,p=0.002)相关.在逻辑回归模型中,较长的睡眠时间与较低的肥胖几率(OR=0.998,95%CI0.997,0.999,p<0.001)和超重状态(OR=0.998,95%CI0.997,0.999,p=0.004)相关.更多的光照(β=6.64*10-5,95%CI3.50*10-5,9.69*10-5,p<0.001)和体育锻炼(β=0.005,95%CI0.004,0.006,p<0.001)与更长的睡眠有关。
结论:儿童睡眠时间延长与血压降低和肥胖程度降低相关。通过增加儿童的体力活动和光照来改善睡眠质量可能会降低心血管疾病的终生风险。
OBJECTIVE: This work aims to assess the association of sleep duration with cardiometabolic risk (adiposity, blood pressure, lipids, albuminuria and A1C) and to investigate lifestyle factors (physical activity, light exposure, caffeine consumption and sugar consumption) associated with sleep duration in children.
METHODS: A nationally representative sample of 3907 children ages 6-17 years enrolled in NHANES from 2011 to 2014 was included in this cross-sectional study. Sleep duration was defined as the daily average time spent sleeping over 7 days as measured by a physical activity monitor (PAM). Participants without valid sleep data for ≥95% of the study were excluded. Regression models were adjusted for age, sex, race, body mass index (BMI) Z score, physical activity and light exposure.
RESULTS: In adjusted regression models, longer sleep duration was associated with lower systolic blood pressure index (β = -3.63 * 10-5, 95% CI -6.99 * 10-5, -2.78 * 10-6, p = 0.035) and BMI Z score (β = -0.001, 95% CI -0.001, 0.000, p = 0.002). In logistic regression models, longer sleep duration was associated with lower odds of obesity (OR = 0.998, 95% CI 0.997, 0.999, p < 0.001) and overweight status (OR = 0.998, 95% CI 0.997, 0.999, p = 0.004). Greater light exposure (β = 6.64 * 10-5, 95% CI 3.50 * 10-5, 9.69 * 10-5, p < 0.001) and physical activity (β = 0.005, 95% CI 0.004, 0.006, p < 0.001) were associated with longer sleep.
CONCLUSIONS: Longer sleep duration was associated with lower blood pressure and adiposity measures in children. Improving sleep quality by increasing physical activity and light exposure in childhood may decrease the lifetime risk of cardiometabolic disease.