biomedical ethics

生物医学伦理学
  • 文章类型: Journal Article
    拥有超过16年的临床经验,研究,以及与经颅磁刺激(TMS)有关的教育活动,我写了这篇文章,探讨了TMS的伦理层面。本文旨在为那些不熟悉TMS以及刚开始在该领域的人提供有价值和信息内容。具体来说,本文阐述了医学伦理学的四项原则,包括适用于TMS治疗的那些,公共医疗保险覆盖面和私人诊所TMS治疗的医疗适应症之间的差距,以及实践中的研究伦理问题。我还提供了有关学术界和这一领域的角色和策略的建议,致力于以适当的方式使更大的患者群体可以接受TMS治疗。最后,我希望这篇文章能成为当代的“TMS神经调节伦理学”,与人类对“真理”的内在追求产生共鸣,天哪,和美丽“为了一个健全的头脑和精神。
    With over 16 years of experience in clinical, research, and educational activities related to transcranial magnetic stimulation (TMS), I have written this article exploring the ethical dimensions of TMS. This article aims to provide valuable and informative content for those unfamiliar with TMS as well as those just starting in the field. Specifically, this article elaborates on four principles of medical ethics, including those applicable to TMS therapy, the disparity between public medical insurance coverage and medical indications in private practice for TMS therapy, and issues concerning research ethics in practice. I also provide recommendations regarding roles and strategies for adoption by academia and those in this field dedicated to making TMS therapy accessible to a larger patient population in a suitable manner. Lastly, it is my hope that this article will serve as a contemporary \"Ethics of TMS Neuromodulation\", resonating with the inherent human pursuit of \"truth, goodness, and beauty\" for a sound mind and spirit.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Letter
    尽管有临床证据表明药物优势,治疗方式,比如联合免疫疗法,大多被认为是成本无效的,因为它们每生命年获得的成本很高。这篇论文,采取道德立场,重新评估标准成本效益分析与较新的司法增强方法的成本效益分析,并指出当前方法的缺点。
    Despite clinical evidence of drug superiority, therapeutic modalities, like combination immunotherapy, are mostly considered cost-ineffective due to their high costs per life year(s) gained. This paper, taking an ethical stand, reevaluates the standard cost-effectiveness analysis with that of the more recent justice-enhanced methods and concludes by pointing out the shortcomings of the current methodologies.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:1926年,FritzJahr将生物伦理学(德语:bio-ethik)描述为“不仅对人类承担道德义务”,而是对所有形式的生命。“Jahr总结了他的哲学,“原则上尊重每一个生命体,把它作为目的本身,并对待它,如果可能,如此!根据1978年的《生物伦理学百科全书》,“生物伦理学最初是一种涉及“干扰其他生物的问题……以及通常与生态系统平衡有关的一切”的伦理体系。这个定义是基于弗里茨·贾尔的工作,MenicoTorchio,还有VanRensselaerPotter.
    方法:为了对起源和主要的生物伦理爆发进行深入的分析,我们将对现有文献进行批判性分析,随后是到相关生物伦理地区的研究之旅(收集有关MenicoTorchio的照片和其他文件)。
    结果:虽然Jahr和Potter通常被认为是发展生物伦理学领域的智力功劳,MenicoTorchio的生态伦理贡献已被遗忘。本文将首先追溯“生物伦理学”的起源-现在通常分为“生物医学伦理学”和“环境生物伦理学”。前者是由乔治敦大学哲学系的TomBeauchamp和宗教研究系的JamesChildress开发的,基于原则,狭隘地关注医疗环境。后者解决了医疗行业对环境的影响和气候变化对健康的危害。第二,我们将呈现Torchio对生物伦理学的重大知识贡献的全景。MenicoTorchio的生物伦理学概念综合了Jahr和Potter的工作,提倡“需要扩大我们的道德义务,拥抱最发达的动物群体,不仅是身体上的,也是心理上的。“第三,今天,我们将反思“生物伦理学”在生物医学和环境生物伦理学上的持久遗产。行星健康和人类健康的相互联系等主题要素,致力于与自然和谐相处,从Tochio的遗产开始,对系统和共生的强调保持不变。
    结论:我们的结论将强调理解行星之间的联系的必要性,环境,和人类健康。
    BACKGROUND: In 1926, Fritz Jahr described bio-ethics (German: bio-ethik) as \"the assumption of moral obligations not only towards humans, but towards all forms of life.\" Jahr summarized his philosophy by declaring, \"Respect every living being on principle as an end in itself and treat it, if possible, as such!.\" Bioethics was thus originally an ethical system concerned with the \"problems of interference with other living beings… and generally everything related to the balance of the ecosystem\" according to the 1978 Encyclopedia of Bioethics. This definition was predicated on the work of Fritz Jahr, Menico Torchio, and Van Rensselaer Potter.
    METHODS: In order to proceed with depthful analysis of the origin and major bioethical flare up, we will use critical analysis of existing literature, followed by a study trip to relevant bioethical localities (collecting photo and other documentations regarding Menico Torchio).
    RESULTS: While Jahr and Potter are typically given intellectual credit for developing the field of bioethics, the eco-ethical contributions of Menico Torchio have been forgotten.This article will first trace the origins of \"bioethics\" - now commonly bifurcated into \"biomedical ethics\" and \"environmental bioethics.\" The former was developed by Tom Beauchamp from the Philosophy Department and James Childress of the Religious Studies department at Georgetown University and is based on principlism, with a narrow focus on medical settings. The latter addresses the environmental impact of the medical industry and climate change health hazards. Second, we will present a panorama of Torchio\'s significant intellectual contribution to bioethics. Menico Torchio\'s concept of bioethics synthesized work of both Jahr and Potter, advocating \"the need to expand our ethical obligations and embrace the most developed groups of animals, not only physically but also psychologically.\" Third, we will reflect on the lasting legacy of \"bioethics\" on biomedical and environmental bioethics today. Thematic elements such as interconnectedness of planetary health and human health, dedication to living in harmony with nature, and emphasis on systems and symbiosis remain unchanged from the legacy of Tochio onward.
    CONCLUSIONS: Our conclusion will underscore the necessity of understanding the connections between planetary, environmental, and human health.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Editorial
    人工智能(AI)在医学中的越来越多的使用与新的道德挑战和责任有关。然而,在将人工智能应用整合到医学教育中时,应特别考虑和关注,在哪里医疗保健,AI,与教育伦理发生碰撞。本评论通过识别潜在的问题和局限性,探讨了医疗机构在将AI应用纳入医学教育中的生物医学伦理责任。目标是实施适用的建议。提出的建议旨在帮助为医学教育工作者和学生制定道德使用人工智能的机构指南。
    The increasing use of artificial intelligence (AI) in medicine is associated with new ethical challenges and responsibilities. However, special considerations and concerns should be addressed when integrating AI applications into medical education, where healthcare, AI, and education ethics collide. This commentary explores the biomedical ethical responsibilities of medical institutions in incorporating AI applications into medical education by identifying potential concerns and limitations, with the goal of implementing applicable recommendations. The recommendations presented are intended to assist in developing institutional guidelines for the ethical use of AI for medical educators and students.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    每天都有许多化学物质和有毒物质释放到我们的生态系统和环境中,会对人类造成有害影响。农业化合物用于大多数作物生产,并已被证明会对健康造成负面影响,包括对生殖和其他病症的影响。虽然这些化学物质有助于害虫和杂草的控制,这些化合物间接影响人类。几种化合物已在欧盟被禁止,但仍在美国使用。最近的工作表明,大多数毒物通过表观遗传比直接暴露的世代对跨代世代的影响更大。虽然有些毒物不会影响直接暴露的世代,后代是跨代或祖先暴露遭受健康影响。由于对后代的影响,暴露成为环境正义问题。术语“环境正义”表示在解决不公正的环境污染时采用公平的策略。公平待遇意味着任何群体都不应承担因工业、市政,和商业运作。本文说明了如何将对直接暴露的世代的研究优先于对跨代世代的研究。然而,对后几代人的研究表明,需要认真对待环境正义问题,因为后代可能会过度承担伤害,而不享受生产的好处。
    Many chemicals and toxicants are released into our ecosystem and environment every day, which can cause harmful effects on human populations. Agricultural compounds are used in most crop production and have been shown to cause negative health impacts, including effects on reproduction and other pathologies. Although these chemicals can be helpful for pest and weed control, the compounds indirectly impact humans. Several compounds have been banned in the European Union but continue to be used in the United States. Recent work has shown most toxicants affect transgenerational generations more than the directly exposed generations through epigenetic inheritance. While some toxicants do not impact the directly exposed generation, the later generations that are transgenerational or ancestrally exposed suffer health impacts. Due to impacts to future generations, exposure becomes an environmental justice concern. The term \"environmental justice\" denotes the application of fair strategies when resolving unjust environmental contamination. Fair treatment means that no group should bear a disproportionate share of negative environmental consequences resulting from industrial, municipal, and commercial operations. This article illustrates how research on directly exposed generations is often prioritized over studies on transgenerational generations. However, research on the latter generations suggests the need to take environmental justice concerns seriously moving forward, as future generations could be unduly shouldering harms, while not enjoying benefits of production.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Systematic Review
    全球老年人的增加需要技术解决方案来应对护理短缺和实现老龄化。从经济和实践的角度来看,智能家居健康技术(SHHT)作为一种可能的解决方案得到了推广和实施。然而,道德考虑同样重要,需要进行调查。
    我们根据PRISMA指南进行了系统评价,以调查是否以及如何在护理老年人的SHHT领域讨论道德问题。
    156篇同行评审文章以英文发表,在10个电子数据库中检索和分析了德语和法语。运用叙事分析,绘制了7个道德类别:隐私,自主性,责任,人类vs.人工相互作用,信任,年龄歧视和耻辱,和其他问题。
    我们的系统评价的结果表明,在制定和实施针对老年人的SHHT时,(缺乏)道德考虑。我们的分析有助于在进行技术开发时促进仔细的道德考虑,研究和部署照顾老年人。
    我们在CRD42021248543下的PROSPERO网络中注册了我们的系统评价。
    The worldwide increase in older persons demands technological solutions to combat the shortage of caregiving and to enable aging in place. Smart home health technologies (SHHTs) are promoted and implemented as a possible solution from an economic and practical perspective. However, ethical considerations are equally important and need to be investigated.
    We conducted a systematic review according to the PRISMA guidelines to investigate if and how ethical questions are discussed in the field of SHHTs in caregiving for older persons.
    156 peer-reviewed articles published in English, German and French were retrieved and analyzed across 10 electronic databases. Using narrative analysis, 7 ethical categories were mapped: privacy, autonomy, responsibility, human vs. artificial interactions, trust, ageism and stigma, and other concerns.
    The findings of our systematic review show the (lack of) ethical consideration when it comes to the development and implementation of SHHTs for older persons. Our analysis is useful to promote careful ethical consideration when carrying out technology development, research and deployment to care for older persons.
    We registered our systematic review in the PROSPERO network under CRD42021248543.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:儿科重症监护病房的大多数死亡涉及放弃维持生命的治疗。这种死亡需要精心策划的基于同情心的临终关怀,并侧重于姑息治疗措施。本研究旨在从多学科团队的角度评估与巴西儿科重症监护病房临终关怀相关的主题。
    方法:作者使用了一份测试问卷,利用李克特风格和开放式问题。伦理委员会批准后,它于2019年9月至11月通过电子邮件发送至巴西南部和东南部的3个儿科重症监护病房.一个单位专门用于肿瘤患者;其他是混合单位。
    结果:从收集的144个调查(23%的响应率)中分析了136个,35%的医生,30%的护士21%的护士技师,14%的物理治疗师做出了回应。总的来说,只有12%的人报告说有足够的临终关怀培训,40%的人报告从未接受过任何培训,尽管这与医生放弃维持生命治疗的信心无关。此外,60%的医生和46%的其他专业人员对不升级比退出疗法更满意。即使这可以延长痛苦。所有医生都对姑息性拔管感到不舒服;所有专业人员中有15%目睹了这种情况。肿瘤学团队独特地认为,“来自专家团队的抵制”是临终护理实施的主要障碍。
    结论:大多数专业人员认为不准备放弃维持生命的治疗。即使是绝症患者,扣留优先于停药。社会文化障碍和缺乏足够的培训可能会导致对绝症患者的护理不安全,与其他国家的做法不同。
    Most deaths in Pediatric Intensive Care Units involve forgoing life-sustaining treatment. Such deaths required carefully planned end-of-life care built on compassion and focused on palliative care measures. This study aims to assess topics related to the end of life care in Brazilian pediatric intensive care units from the perspective of a multidisciplinary team.
    The authors used a tested questionnaire, utilizing Likert-style and open-ended questions. After ethics committee approval, it was sent by email from September to November/2019 to three Pediatric Intensive Care Units in the South and Southeast of Brazil. One unit was exclusively dedicated to oncology patients; the others were mixed units.
    From 144 surveys collected (23% response rate) 136 were analyzed, with 35% physicians, 30% nurses, 21% nurse technicians, and 14% physiotherapists responding. Overall, only 12% reported enough end-of-life care training and 40% reported never having had any, albeit this was not associated with the physician\'s confidence in forgoing life-sustaining treatment. Furthermore, 60% of physicians and 46% of other professionals were more comfortable with non-escalation than withdrawing therapies, even if this could prolong suffering. All physicians were uncomfortable with palliative extubation; 15% of all professionals have witnessed it. The oncologic team uniquely felt that \"resistance from the teams of specialists\" was the main barrier to end-of-life care implementation.
    Most professionals felt unprepared to forego life-sustaining treatment. Even for terminally ill patients, withholding is preferred over the withdrawal of treatment. Socio-cultural barriers and the lack of adequate training may be contributing to insecurity in the care of terminally ill patients, diverging from practices in other countries.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    人类细胞图谱(HCA)正在努力建立一个开放的社区,包括所有遵守其原则的研究人员,并在数据访问和使用方面尽可能开放。然而,开放的数据共享可能会带来一定的挑战。例如,作为一项全球倡议,HCA必须与当地和地区隐私规则的拼凑而成。一个值得注意的例子是欧盟通用数据保护条例(GDPR)的实施。这引起了生物医学和基因组数据共享界的一些关注。我们检查HCA有多大,国际研究人员小组正在投入巨大的努力来确保适当的数据共享。我们描述了HCA的目标和治理,它如何定义开放数据共享,以及在其发展初期遇到的伦理法律挑战;特别是,我们描述了GDPR带来的挑战。最后,我们扩大了讨论范围,以解决可用于解决道德数据治理的工具和策略。基因组学和人类遗传学年度评论的预期最终在线出版日期,第24卷是2023年8月。请参阅http://www。annualreviews.org/page/journal/pubdates的订正估计数。
    The Human Cell Atlas (HCA) is striving to build an open community that is inclusive of all researchers adhering to its principles and as open as possible with respect to data access and use. However, open data sharing can pose certain challenges. For instance, being a global initiative, the HCA must contend with a patchwork of local and regional privacy rules. A notable example is the implementation of the European Union General Data Protection Regulation (GDPR), which caused some concern in the biomedical and genomic data-sharing community. We examine how the HCA\'s large, international group of researchers is investing tremendous efforts into ensuring appropriate sharing of data. We describe the HCA\'s objectives and governance, how it defines open data sharing, and ethico-legal challenges encountered early in its development; in particular, we describe the challenges prompted by the GDPR. Finally, we broaden the discussion to address tools and strategies that can be used to address ethical data governance.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    在本文中,我将审查美国最高法院(SCOTUS)在Dobbs诉Jackson妇女健康组织的多数决定中的论点,我将展示其中一些论点是有缺陷的。首先,我将证明身体自主权是一项既定的权利,无论是在法庭上还是在社会实践中,堕胎权应被理解为身体自主权或身体完整权的一个例子。第二,我将研究法官的论点,即生存能力不是限制堕胎的合理场所,与Roev.Wade和PlannedParenthoodv.Casey相比,并将提供捍卫生存能力的论据,作为限制堕胎机会的有效观点。第三,我将强调一些政客制定联邦堕胎禁令的目标,并展示通过人格修正案的尝试是如何实现这一目标的。这篇文章的结果是展示了SCOTUS的决定是有缺陷的,以及赋予人格“潜在生命”的后果如何超出堕胎的范围。
    In this paper, I will examine the Supreme Court of the United States\' (SCOTUS) arguments in the majority decision in Dobbs v. Jackson Women\'s Health Organization, and I will show how some of those arguments are flawed. Primarily, I will show that the right to bodily autonomy is a well-established right, both in the courts and in societal practices, and that the right to an abortion should be understood as an example of the right to bodily autonomy or bodily integrity. Second, I will examine the justices\' arguments that viability is not a reasonable place to restrict abortion access, in contrast to both Roe v. Wade and Planned Parenthood v. Casey, and will offer arguments that defend viability as a valid point to limit abortion access. Third, I will highlight some politicians\' goals to enact a federal ban on abortion, and show how the attempt to pass Personhood Amendments is a pathway for doing so. The upshot of this essay to is show how the SCOTUS decision is flawed, and how granting personhood to \"potential life\" has consequences that extend beyond abortion access.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号