管道内表面的生物膜形成对配水系统构成了重大威胁,增加维护成本,损害公众健康。为了解决这个巨大的问题,我们合成了由阿拉伯胶(AG)和壳聚糖(Cs)组成的纳米凝胶,负载不同浓度的银纳米粒子(AgNPs),用作抗菌涂层。使用AG作为还原剂和稳定剂合成AgNPs,在414nm处显示吸光度。使用TEM确认AgNP的均匀颗粒。对大肠杆菌的杀菌效果进行了评估,肺炎克雷伯菌,粪肠球菌,和枯草芽孢杆菌.使用浸涂法,涂覆两种管材(聚丙烯(PP)和球墨铸铁(DI)),揭示了革兰氏阳性细菌的较小抑制区。值得注意的是,AgNPs2@AGCsNG纳米凝胶表现出有效的抗菌作用。毒性测试证实了纳米凝胶的安全性,建议广泛的应用。高EC50%值强调了它们的无毒性质。这项研究提出了一种有效的水系统生物膜预防策略,提供优异的抗菌性能和生物相容性。载有AgNP的AG和Cs纳米凝胶有望提高水质,降低维修价格,并在供水网络中保护人类公共健康。
Biofilm formation on the inner surfaces of pipes poses significant threats to water distribution systems, increasing maintenance costs and public health risks. To address this immense issue, we synthesized a nanogel formulation comprising acacia gum (AG) and chitosan (Cs), loaded with varying concentrations of silver nanoparticles (AgNPs), for using as an antimicrobial coating material. AgNPs were synthesized using AG as a reducing and stabilizing agent, exhibiting absorbance at 414 nm. The preparation of AgNPs was proved using TEM. Bactericidal efficacy was assessed against E. coli, Klebsiella pneumoniae, Enterococcus faecalis, and Bacillus subtilis. Using the dipping coating method, two pipe materials (polypropylene (PP) and ductile iron (DI)) were successfully coated. Notably, AgNPs2@AGCsNG nanogel exhibited potent antibacterial action against a wide range of pathogenic bacteria. Toxicity tests confirmed nanogel safety, suggesting broad applications. High EC50% values underscored their non-toxic nature. This research proposes an effective strategy for biofilm prevention in water systems, offering excellent antibacterial properties and biocompatibility. AG and Cs nanogels loaded with AgNPs promise to enhance water quality, reduce maintenance prices, and protect human public health in water distribution networks.