在这项研究中,利用浸渍有Fe3O4纳米颗粒的蛋壳合成了一种可生物降解且环保的生物催化剂(蛋壳/Fe3O4)。通过傅里叶变换红外辐射(FT-IR)对制备的催化剂进行了表征,扫描电子显微镜(SEM),X射线衍射(XRD)能量色散X射线(EDX),热重分析-差示热重分析(TGA-DTG),振动样品磁强计(VSM),和原子力显微镜(AFM)。蛋壳/Fe3O4生物催化剂用于多组分反应(MCR),用于从各种芳香醛合成2-氨基噻吩衍生物,丙二腈,乙酰乙酸乙酯,和硫(S8)。为了达到最佳反应条件,对关键因素进行了彻底检查,例如溶剂类型,反应时间和温度,和蛋壳与Fe3O4的比例。结果表明,在微波温度(MW)下,在EtOH溶剂中10分钟内可以获得高产率产物。此外,蛋壳/Fe3O4生物催化剂表现出较高的催化活性,这是在五个周期内持续的,其业绩没有任何显著下降。
In this study, a biodegradable and eco-friendly
biocatalyst (eggshell/Fe3O4) was synthesized utilizing eggshell impregnated with Fe3O4 nanoparticles. The characterization of prepared catalyst was carried out by Fourier transform infrared radiation (FT-IR), scanning electron microscopy (SEM), X-ray Diffraction (XRD), energy-dispersive X-ray (EDX), thermal gravimetric analysis-differential thermogravimetry (TGA-DTG), vibrating sample magnometer (VSM), and atomic force microscopy (AFM). The eggshell/Fe3O4
biocatalyst was served in multi-component reactions (MCRs) for the synthesis of 2-amino thiophene derivatives from variety aromatic aldehydes, malononitrile, ethyl acetoacetate, and sulfur (S8). To achieve optimal reaction conditions, a thorough examination was conducted on key factors, such as the solvent type, reaction time and temperature, and the ratio of eggshell to Fe3O4. The findings suggest that high yield product can be obtained at microwave temperature (MW) in EtOH solvent within 10 min. Additionally, the eggshell/Fe3O4
biocatalyst exhibited high catalytic activity, which was sustained over the five cycles, without any significant decline in its performance.