■分析和总结西北地区急性呼吸道感染(ARIs)的病原学和流行病学特征,以改善局部ARIs的临床管理和预防。
■陕西省ARIs患者,2014年1月至2018年12月,进行回顾性分析.采用间接免疫荧光法(IFA)检测8种呼吸道病原体的IgM抗体。
■本研究共纳入15,543名符合条件的患者。总的来说,36.01%的患者(5597/15543)对八种病原体中的至少一种呈阳性,其中单一和混合感染占74.65%(4178/5597)和25.35%(1419/5597),分别。支原体(MP)检出率最高(18.12%),其次是乙型流感病毒(乙型流感,11.65%),衣原体(CP,7.00%),呼吸道合胞病毒(RSV,4.18%),副流感病毒(PIV,2.83%),甲型流感病毒(甲型流感,1.69%),军团菌(LP,1.00%)和腺病毒(ADV,0.70%)。乙型流感(17.54%,759/4327)是18岁以下患者中最流行的病毒。此外,秋季发现了检出率较高的常见呼吸道感染(39.65%),其次是冬季(37.37%),夏季(36.21%)和春季(30.91%)。不同季节病原菌检出率差异有统计学意义(P<0.001)。
■这些发现可为当地卫生当局制定预防和控制ARIs的进一步计划提供参考。
UNASSIGNED: To analyze and summarize the etiological and epidemiological characteristics of acute respiratory tract infections (ARIs) in northwest China to improve the clinical management and prevention of local ARIs.
UNASSIGNED: Patients with ARIs in Shaanxi Province, from January 2014 to December 2018, were retrospectively analyzed. Indirect immunofluorescence assay (IFA) was used to detect the IgM antibody of eight respiratory pathogens.
UNASSIGNED: A total of 15,543 eligible patients were included in this study. Overall, 36.01% of the patients (5597/15543) were positive for at least one of eight pathogens, among which single and mixed infections accounted for 74.65% (4178/5597) and 25.35% (1419/5597), respectively. Mycoplasma (MP) showed the highest detection rate (18.12%), followed by influenza virus B (Flu B, 11.65%), chlamydia (CP, 7.00%), respiratory syncytial virus (RSV, 4.18%), parainfluenza virus (PIV, 2.83%), influenza virus A (Flu A, 1.69%), legionella (LP, 1.00%) and adenovirus (ADV, 0.70%). Flu B (17.54%, 759/4327) was the most prevalent virus in patients aged less than 18 years. In addition, common respiratory infections with higher detection rates were found in autumn (39.65%), followed by winter (37.37%), summer (36.21%) and spring (30.91%). There were significant differences in the detection rates of pathogens in different seasons (P < 0.001).
UNASSIGNED: These findings serve as a reference for local health authorities to develop further plans for the prevention and control of ARIs.