applied research

应用研究
  • 文章类型: Journal Article
    随着社会对环境资源的重视,目前食品行业以石油为主的包装已经不能满足人们的需求。然而,新的主动包装技术已经出现,如蛋白质,多糖,和脂质,其中蛋白质因其优异的凝胶成膜性能而被广泛使用。当前的大多数文献集中于基于单一蛋白质的膜的研究应用。在本文中,我们回顾了近年来用于对不同蛋白质进行分类的新型蛋白质包装技术,包括植物蛋白(大豆分离蛋白,zein,谷蛋白)和动物蛋白(乳清蛋白分离物,酪蛋白,胶原蛋白,明胶)。最近在基于蛋白质的活性包装技术方面取得的进展可以通过描述蛋白质来源来理解,凝胶特性,成型原理,和应用研究。本文提出了目前活性包装技术存在的问题和前景,为今后新型包装的开发和凝胶应用的拓展提供了新思路,促进环保食品包装的发展和创新。
    With the emphasis placed by society on environmental resources, current petroleum-based packaging in the food industry can no longer meet people\'s needs. However, new active packaging technologies have emerged, such as proteins, polysaccharides, and lipids, in which proteins are widely used for their outstanding gel film-forming properties. Most of the current literature focuses on research applications of single protein-based films. In this paper, we review the novel protein-based packaging technologies that have been used in recent years to categorize different proteins, including plant proteins (soybean protein isolate, zein, gluten protein) and animal proteins (whey protein isolate, casein, collagen, gelatin). The advances that have recently been made in protein-based active packaging technology can be understood by describing protein sources, gel properties, molding principles, and applied research. This paper presents the current problems and prospects of active packaging technology, provides new ideas for the development of new types of packaging and the expansion of gel applications in the future, and promotes the development and innovation of environmentally friendly food packaging.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Editorial
    转化研究将实验室生成的科学发现应用于现实世界的实践,目的是加强更快速的健康挑战解决方案。2023年,这篇社论的作者(希尔德布兰特和戈德施密特)旨在为《国际饮食失调杂志》(IJED)开发一期特刊,重点是翻译饮食失调研究。这个问题的目标是开始缩小基础和应用研究之间的差距,通过征集文章,提高我们对导致或维持饮食失调的机制的理解,这可能会导致更强大的研究进展和向公众传播信息。该问题的进一步目标包括使IJED的读者接受广泛的翻译研究,并激发新的合作努力。虽然收到了强有力的意见书,在征集足够多的文章时遇到了挑战,这可能反映了饮食失调领域基础和临床科学家之间长期存在的沟通障碍。在这篇社论中,我们强调特别部分中包含的工作,确定翻译饮食失调研究中的潜在障碍,并提供多管齐下的方法来支持整个翻译谱更快的进展。通过改进我们的领域如何进行转化研究,我们可以为那些有饮食失调或有饮食失调风险的人带来更好的结果。
    Translational research applies laboratory-generated scientific discoveries to real-world practice with the goal of potentiating more rapid solutions to health challenges. In 2023, the authors of this editorial (Hildebrandt and Goldschmidt) aimed to develop a special issue for the International Journal of Eating Disorders (IJED) focusing on translational eating disorder research. The goal for this issue was to begin closing the gap between basic and applied research by soliciting articles that improve our understanding of mechanisms that cause or maintain eating disorders, which could result in more robust research advances and dissemination of information to the public. Further goals for the issue included exposing IJED\'s readership to a wide range of translational research and inspiring new collaborative efforts. While strong submissions were received, challenges were encountered in soliciting enough articles, potentially reflecting long-standing communication barriers between basic and clinical scientists within the eating disorders field. In this editorial, we highlight work included in the special section, identify potential barriers in translational eating disorder research, and offer a multipronged approach to support more rapid progress across the translational spectrum. By improving how our field approaches translational research, we can promote better outcomes for those with or at risk for eating disorders.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    黑果枸杞在食品和医药上都有重要的应用,包括抗氧化,抗肿瘤,抗疲劳,抗炎,和其他各种影响。因此,致力于探索其潜在好处的研究工作激增,需要组织和综合这些发现。本文系统综述了多糖等活性物质的提取和含量测定方法,花青素,黄酮类化合物,在过去的五年里,LRM中的多酚,以及一些活性成分的测定方法,生物活动,和产品开发。本综述主要分为三个部分:提取和测定方法,它们的生物活性,和产品开发。在先前研究的基础上,我们还深入研究了黑果枸杞的经济和药用价值,从而大大有助于其进一步的探索和发展。预计这项全面的审查将成为推进黑果枸杞研究的宝贵资源。
    Lycium ruthenicum Murray possesses significant applications in both food and medicine, including antioxidative, anti-tumor, anti-fatigue, anti-inflammatory, and various other effects. Consequently, there has been a surge in research endeavors dedicated to exploring its potential benefits, necessitating the organization and synthesis of these findings. This article systematically reviews the extraction and content determination methods of active substances such as polysaccharides, anthocyanins, flavonoids, and polyphenols in LRM in the past five years, as well as some active ingredient composition determination methods, biological activities, and product development. This review is divided into three main parts: extraction and determination methods, their bioactivity, and product development. Building upon prior research, we also delve into the economic and medicinal value of Lycium ruthenicum Murray, thereby contributing significantly to its further exploration and development. It is anticipated that this comprehensive review will serve as a valuable resource for advancing research on Lycium ruthenicum Murray.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    对目标文章“概括:圣杯和小牛”的五个评论(鲍尔,2023年)为心理科学的概括问题提供了思考的食物。一般来说,在该领域似乎达成了共识,即对心理科学研究结果的普遍性的未被认可的限制是一个令人严重关切的问题。对评论的答复详细阐述了这一基本共识,并讨论了与目标文章中论点的其他汇合点。答复还涉及目标文章和评论之间的分歧领域,以及评论本身。答复在评论的启发下提出了前进道路的建议。呼应目标文章,答复要求在心理科学研究中提高真实性,将加强全方位调查努力的运动,从基础到应用。
    The five commentaries on the target article \"Generalizations: The Grail and the Gremlins\" (Bauer, 2023) provide food for thought on the issue of generalizations in psychological science. Generally speaking, there seems to be agreement in the field that unrecognized limits on the generalizability of the findings of psychological science research are a matter of serious concern. This reply to the commentaries features elaboration of this basic point of agreement as well as discussion of other points of convergence with the arguments in the target article. The reply also addresses areas of divergence between the target article and the commentaries, and among the commentaries themselves. The reply develops suggestions for ways forward inspired by the commentaries. Echoing the target article, the reply calls for greater authenticity in psychological science research, movement toward which would strengthen efforts along the full range of inquiry, from basic to applied.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    我们与其他人一起设想情感科学的未来,以解决社会最紧迫的需求。为了朝着这个愿景前进,我们考虑在其他学科中出现的研究范式:使用启发的基础研究。这种范式超越了传统的基本应用二分法,它将基本科学认识的基本目标与解决社会问题的应用目标对立起来。在现实中,这些目标是相辅相成的,和使用启发的基础研究同时推进它们。这里,我们为使用启发的基础研究建立了一个案例-它与传统基础科学有何不同,以及为什么情感科学家应该参与其中。我们首先研究受使用启发的基础研究如何挑战严格的基本应用二分法的有问题的假设。然后,我们讨论它如何与情感科学的进步相一致,情感科学将上下文特异性视为规范,并将使用的伦理问题视为补充目标。在这一理论讨论之后,我们将使用启发基础研究的实施与传统基础科学的实施区分开来。我们借鉴了最近研究的例子来说明差异:以社会问题为起点,利益相关者和社区参与,研究与服务的整合。总之,我们邀请情感科学家接受“实验室与世界”的观点,即使用启发的基础研究,作为通往现实世界影响的有希望的途径。
    We join others in envisioning a future for affective science that addresses society\'s most pressing needs. To move toward this vision, we consider a research paradigm that emerged in other disciplines: use-inspired basic research. This paradigm transcends the traditional basic-applied dichotomy, which pits the basic goal of fundamental scientific understanding against the applied goal of use in solving social problems. In reality, these goals are complementary, and use-inspired basic research advances them simultaneously. Here, we build a case for use-inspired basic research-how it differs from traditional basic science and why affective scientists should engage in it. We first examine how use-inspired basic research challenges problematic assumptions of a strict basic-applied dichotomy. We then discuss how it is consistent with advances in affective science that recognize context specificity as the norm and consider ethical issues of use being a complementary goal. Following this theoretical discussion, we differentiate the implementation of use-inspired basic research from that of traditional basic science. We draw on examples from recent research to illustrate differences: social problems as a starting point, stakeholder and community engagement, and integration of research and service. In conclusion, we invite affective scientists to embrace the \"lab meets world\" perspective of use-inspired basic research as a promising pathway to real-world impact.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    The practice of rural construction has been exploring and trying to adapt to the needs of rural development in various periods. In recent years, under the attention and promotion of the central policy, various social forces have joined the ranks of rural construction, and art intervention in rural construction has begun as a new method. Entering the public eye, it deeply intervenes in the construction and development of the countryside in a more gentle way, from the key point of interaction between the social and cultural orientation and the material needs of the countryside. However, most of the art interventions in rural construction practice only unilaterally use artistic techniques to beautify local areas or display works, without realizing the hidden artistic and cultural value of the village and ignoring the participation and role of the villagers in the whole process. After the construction is completed, once the foreign construction forces are withdrawn, the development of the village will stagnate. Therefore, mobilizing the main body of rural construction (original villagers) to participate in the joint construction of the village is an important link to solve the current problems of art intervening in the construction of rural settlements.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:在儿科医疗保健服务中,关于患者健康状况的患者报告结果(PRO)主要用于慢性护理环境中的研究目的。然而,PROs还应用于临床环境中,对患有慢性健康状况的儿童和青少年进行常规护理。PROs有可能涉及患者,因为他们“将患者置于他或她的治疗中心”。关于PROs如何用于儿童和青少年治疗以及这种使用如何影响这些患者的参与的研究仍然有限。这项研究的目的是调查1型糖尿病(T1D)的儿童和青少年如何在治疗中使用PRO,重点是参与的经验。
    结果:采用解释性描述,对患有T1D的儿童和青少年进行了20次半结构化访谈。分析揭示了与使用PRO相关的四个主题:为对话腾出空间,在适当的情况下应用PRO,问卷结构和内容,成为医疗保健的合作伙伴。
    结论:结果阐明,在某种程度上,专业人士履行他们承诺的潜力,包括以患者为中心的沟通,检测未识别的问题,加强患者-临床医生(和家长-临床医生)伙伴关系,增加病人的自我反省。然而,如果要充分发挥PRO在儿童和青少年治疗中的潜力,就需要进行调整和改进。
    Within pediatric health care services, Patient-reported Outcomes (PROs) regarding the patient\'s health status are mainly used for research purposes in a chronic care setting. However, PROs are also applied in clinical settings in the routine care of children and adolescents with chronic health conditions. PROs have the potential to involve patients because they \'place the patient at the center\' of his or her treatment. The investigation of how PROs are used in the treatment of children and adolescents and how this use can influence the involvement of these patients is still limited. The aim of this study was to investigate how children and adolescents with type 1 diabetes (T1D) experience the use of PROs in their treatment with a focus on the experience of involvement.
    Employing Interpretive Description, 20 semi-structured interviews were conducted with children and adolescents with T1D. The analysis revealed four themes related to the use of PROs: Making room for conversation, Applying PROs under the right circumstances, Questionnaire structure and content, and Becoming partners in health care.
    The results clarify that, to some extent, PROs fulfill the potential they promise, including patient-centered communication, detection of unrecognized problems, a strengthened patient-clinician (and parent-clinician) partnership, and increased patient self-reflection. However, adjustments and improvements are needed if the potential of PROs is to be fully achieved in the treatment of children and adolescents.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:针对COVID-19的澳大利亚首批X(FFX)家用传输项目是第一个有前景的项目,澳大利亚同类多辖区研究。该项目是联邦和州卫生部门与澳大利亚传染病紧急情况防备研究伙伴关系(APPRISE)之间的合作伙伴关系,并于2020年4月至10月活跃。
    方法:我们旨在确定和探索澳大利亚FFX项目的挑战和优势,为未来的FFX研究发展和纳入大流行准备计划提供信息。我们要求参与实施的主要利益相关者和合作伙伴在两轮修改后的Delphi调查中确定和排名与项目实施的优势和挑战有关的因素。然后采访了来自管辖卫生部门的主要代表,以将公共卫生过程中的发现与信息需求联系起来,为澳大利亚的FFX研究开发制定最终建议。
    结果:从评估中得出了四个明确的建议。未来的准备计划应旨在使卫生部门和研究人员之间的伙伴关系正规化和嵌入,以帮助更好地将项目数据收集纳入核心公共卫生监测活动。功能的发展,评估参与者指出,具有预先建立的道德和治理批准的适应性协议以及对国家数据基础设施的投资是其他优先领域。
    结论:评估提供了一个很好的机会,可以巩固从澳大利亚FFX家庭传输项目中吸取的经验教训。制定的建议应纳入澳大利亚未来的大流行准备计划,以便在紧急公共卫生响应中有效实施并增加FFX平台的本地效用和价值。
    The Australian First Few X (FFX) Household Transmission Project for COVID-19 was the first prospective, multi-jurisdictional study of its kind in Australia. The project was undertaken as a partnership between federal and state health departments and the Australian Partnership for Preparedness Research on Infectious Disease Emergencies (APPRISE) and was active from April to October 2020.
    We aimed to identify and explore the challenges and strengths of the Australian FFX Project to inform future FFX study development and integration into pandemic preparedness plans. We asked key stakeholders and partners involved with implementation to identify and rank factors relating to the strengths and challenges of project implementation in two rounds of modified Delphi surveys. Key representatives from jurisdictional health departments were then interviewed to contextualise findings within public health processes and information needs to develop a final set of recommendations for FFX study development in Australia.
    Four clear recommendations emerged from the evaluation. Future preparedness planning should aim to formalise and embed partnerships between health departments and researchers to help better integrate project data collection into core public health surveillance activities. The development of functional, adaptable protocols with pre-established ethics and governance approvals and investment in national data infrastructure were additional priority areas noted by evaluation participants.
    The evaluation provided a great opportunity to consolidate lessons learnt from the Australian FFX Household Transmission Project. The developed recommendations should be incorporated into future pandemic preparedness plans in Australia to enable effective implementation and increase local utility and value of the FFX platform within emergency public health response.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: English Abstract
    目的:从胃癌手术切除标本中及时获取全面准确的淋巴结信息是判断病理分期准确性和预测患者预后的重要指标。
    方法:使用分类和分析系统进行淋巴结分类,图像数据收集和存储,术中或术后立即对胃癌淋巴组织进行智能软件分析。
    结果:系统获得的淋巴结数量明显高于传统方法获得的淋巴结数量,缩短了分拣时间,淋巴结分选遗漏率降低,提高了分选效率。
    结论:临床应用排序分析系统可有效提高胃癌分期符合率,对患者的预后评估和最佳治疗方案的选择具有非常重要的作用。
    OBJECTIVE: Timely acquisition of comprehensive and accurate lymph node information from surgically resected specimens of gastric cancer is an important indicator for determining the accuracy of pathological staging and predicting the prognosis of patients.
    METHODS: Use the sorting and analysis system to perform lymph node sorting, image data collection and storage, and intelligent software analysis for gastric cancer lymphoid tissue immediately during or after surgery.
    RESULTS: The number of lymph nodes obtained by the system was significantly higher than that obtained by the traditional method, the sorting time was shortened, the omission rate of lymph nodes sorting was reduced, the sorting efficiency was improved.
    CONCLUSIONS: The clinical application of sorting and analysis system can effectively improve the coincidence rate of gastric cancer staging, plays a very important role in the prognosis evaluation of patients and the selection of the best treatment plan.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    要求美国卫生系统进行社区健康需求评估(CHNA)。这些评估通常仅依赖于公开报告的疾病患病率数据。这项研究的目的是确定一种可行的定性方法,可以在CHNA中实施,以确认现有信息并通过新数据和社区叙述来增强它们。2017年在宾夕法尼亚州的一个县进行了自由访谈。个人列出(1)改善健康的东西,(2)健康问题,(3)健康障碍。回答被分成类似的术语,计算了史密斯的显著性指数,评估亚组变异。社区报告的健康优先事项是通过与公开报告的疾病患病率数据并列的突出术语来确定的。全县98名受访者参加了自由访谈。人口统计学与人口相似:平均年龄55岁,46%为女性,88%白种人,9%没有保险。改善健康的主要术语包括:“身体活动”,“健康饮食”,和“卫生服务”。描述健康问题的主要术语包括:“心血管疾病”和“脊柱和关节疾病”。疾病控制和预防中心(CDC)报告的该县慢性病患病率包括心脏病死亡率(22%的死亡)和关节炎(26%的成年人)。健康的主要障碍包括:“体重,身体活动,和饮食问题,“以及“职业问题”。这与2017年与肥胖相关的县健康排名(报告29%)一致。然而,10%的人在社区没有保险,这不是一个突出的术语。自由列表可以扩大和告知CHNA。在这项单县研究中,自由列表的回答支持公开的疾病/死亡率患病率数据,并提供了对社区对健康问题的看法的见解。
    US health systems are required to conduct community health needs assessments (CHNAs). These assessments often rely solely on publicly reported disease prevalence data. The objective of this study was to identify a feasible qualitative method that can be implemented into CHNAs to confirm existing information and enhance them with new data and community narrative. Freelisting interviews were conducted in 2017 throughout a county in Pennsylvania. Individuals listed (1) things that improve health, (2) health problems, and (3) health barriers. Responses were grouped into like terms, Smith\'s salience index was calculated for each, subgroup variation was assessed. Community-reported health priorities were identified by salient terms juxtaposed with publicly reported disease prevalence data. 98 respondents throughout the county participated in freelisting interviews. Demographics resembled the population: median age 55, 46% female, 88% Caucasian, 9% uninsured. Salient terms that improve health included: \"physical activity\", \"healthy eating\", and \"health services\". Salient terms describing health problems included: \"cardiovascular disease\" and \"spine and joint disease\". Centers for Disease Control and Prevention (CDC)-reported chronic disease prevalence in the county included heart disease mortality (22% of deaths) and arthritis (26% of adults). Salient barriers to health included: \"weight, physical activity, and dietary concerns\", as well as \"occupational concerns\". This is in line with 2017 County Health Rankings related to obesity (reported 29%), however, while 10% were uninsured in the community, this was not a salient term. Freelisting can augment and inform CHNAs. In this single-county study, freelisting responses supported publicly available disease/mortality prevalence data and provided insight into community perceptions of health issues.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号