衰弱是老年人群中重要的公共卫生和临床问题。这项研究旨在评估台湾老年人的营养状况和肾功能与虚弱的关系。
我们对嘉义县的老年人群进行了基于社区的健康调查,台湾,从2017年到2019年。
我们测量了营养状况(包括血清白蛋白和总蛋白水平),肾功能(包括血清尿素氮,肌酐,尿蛋白,和尿肌酐水平),手握力(GS)和计算的阑尾肌肉质量(AMM)。
这项研究招募了3739名参与者(2139名女性)。GS正常的男女参与者的血清白蛋白水平较高,尿蛋白/肌酐比率(UPCRs)较低。对于GS正常和弱的男人来说,血清白蛋白水平分别为4.15±0.2和4.10±0.2g/dL(p<0.01),UPCRs分别为123.1±219.6和188.7±366.2(p<0.001),分别。GS与血清白蛋白和尿肌酐水平呈正相关(r=0.136和0.177,均p<0.001)。AMM还与血清白蛋白和尿肌酐水平呈正相关(r=0.078和0.091,均p<0.001)。在多元回归模型中,血清白蛋白水平每增加1g/dL,男性和女性的GS分别增加了1.9和1.7公斤(p<0.05和p<0.01),分别。预测GS的最终模型包括年龄,白蛋白,BUN,UPCR(女性尿肌酐)的差异为22.1%和13.8%,分别。
合理的膳食营养摄入和维持肾功能是台湾老年人群预防虚弱的关键因素。
Frailty is a significant public health and clinical issue among the elder population. This study aimed to evaluate the nutritional status and renal function in relation to frailty among elderly Taiwanese.
We administered community-based health surveys to the elder population in Chiayi County, Taiwan, from 2017 to 2019.
We measured nutritional status (including serum albumin and total protein levels), renal function (including serum blood urea nitrogen, creatinine, urine protein, and urine creatinine levels), hand grip strength (GS) and calculated appendicular muscle mass (AMM).
The study recruited 3739 participants (2139 women). Participants of both sexes with normal GS had higher serum albumin levels and lower urine protein/creatinine ratios (UPCRs). For the men with normal and weak GS, serum albumin levels were 4.15 ± 0.2 and 4.10 ± 0.2 g/dL (p < 0.01), and UPCRs were 123.1 ± 219.6 and 188.7 ± 366.2 (p < 0.001), respectively. GS was positively correlated with serum albumin and urine creatinine levels (r = 0.136 and 0.177, both p < 0.001). AMM was also positively correlated with serum albumin and urine creatinine levels (r = 0.078 and 0.091, both p < 0.001). In the multivariate regression model, for every 1 g/dL increase in serum albumin level, there was a 1.9 and 1.7-kg increase in GS for men and women (p < 0.05 and p < 0.01), respectively. The final model for predicting GS included age, albumin, BUN, and UPCR (urine creatinine for women) which presented a variance of 22.1% and 13.8%, respectively.
Proper dietary nutritional intake and maintaining renal function are key elements for preventing frailty among elder population in Taiwan.