■该体外研究旨在评估和比较小豆豆(0.5%)漱口水的抗菌功效,山茶(0.5%)漱口水,和0.12%葡萄糖酸氯己定漱口水对变形链球菌的作用。
制备5种漱口水制剂的总共60个样品以检查它们的抗微生物功效。针对变形链球菌的抑制区(ZOI)测量为以mm为单位的直径,漱口水制剂的最小抑制浓度(MIC)为μg/mL。使用Mann-WhitneyU检验和Kruskal-Wallis检验对所有组进行统计学比较。
■在第V组葡萄糖酸氯己定中观察到最高的ZOI[平均值:20.8,标准偏差(SD):0.58],其次是III组C.sinensis(无酒精)(平均值:15.5,SD:0.67),IV组C.sinensis(基于酒精)(平均:14.08,SD:0.66),和II组E.cardamomum(醇基)(平均值:13.2,SD:0.45)。在I组中观察到最少的ZOI。豆角肠球菌(无酒精)(平均值:10.7,SD:0.45)。这种差异具有统计学意义(p<0.01)。所有组的MIC相似(p=0.13)。
■0.12%葡萄糖酸氯己定漱口水显示出最佳的抗菌作用;然而,C.sinensis漱口水显示出对抗变形链球菌的潜力。E.cardamomum漱口水表现出有限的抗微生物活性。
■DeolikarS,JawdekarA,SarafT,etal.比较评估小豆蔻(0.5%)漱口水的抗菌效果,茶树(0.5%)漱口水,和0.12%葡萄糖酸氯己定漱口水对变形链球菌的体外研究。IntJClinPediatrDent2024;17(4):461-466。
UNASSIGNED: The in vitro study aimed to evaluate and compare the antimicrobial efficacy of Elettaria cardamomum (0.5%) mouthwash, Camellia sinensis (0.5%) mouthwash, and 0.12% chlorhexidine gluconate mouthwash against Streptococcus mutans.
UNASSIGNED: A total of 60 samples of the five mouthwash preparations were prepared to check for their antimicrobial efficacy. The zone of inhibition (ZOI) against S. mutans was measured as a diameter in mm, and the minimum inhibitory concentration (MIC) of mouthwash preparations was measured as μg/mL. All the groups were compared statistically using the Mann-Whitney U test and the Kruskal-Wallis test.
UNASSIGNED: The highest ZOI was observed in group V chlorhexidine gluconate [mean: 20.8, standard deviation (SD): 0.58], followed by group III C. sinensis (alcohol-free) (mean: 15.5, SD: 0.67), group IV C. sinensis (alcohol-based) (mean: 14.08, SD: 0.66), and group II E. cardamomum (alcohol-based) (mean: 13.2, SD: 0.45). The least ZOI was observed in group I E. cardamomum (alcohol-free) (mean: 10.7, SD: 0.45). This difference was statistically significant (p < 0.01). The MIC was similar in all the groups (p = 0.13).
UNASSIGNED: Chlorhexidine gluconate 0.12% mouthwash showed the best antimicrobial action; however, C. sinensis mouthwash showed potential against S. mutans. E. cardamomum mouthwash exhibited limited antimicrobial activity.
UNASSIGNED: Deolikar S, Jawdekar A, Saraf T, et al. Comparative Evaluation of the Antimicrobial Efficacy of Elettaria cardamomum (0.5%) Mouthwash, Camellia sinensis (0.5%) Mouthwash, and 0.12% Chlorhexidine Gluconate Mouthwash against Streptococcus mutans: An In Vitro Study. Int J Clin Pediatr Dent 2024;17(4):461-466.