目的:抗生素耐药性(ABR)是对公众健康的主要威胁。医院医疗保健专业人员是遏制ABR的重要利益相关者。为了能够鼓励医疗保健专业人员对ABR采取行动,需要关于他们看法的信息。然而,关于医疗保健专业人员如何看待ABR原因的总结证据,后果,解决方案已经过时了。这篇综述旨在阐明这些看法。
方法:我们搜索了MEDLINE,EMBASE,PsycINFO,和CINAHL的文献发表到7月6日,2022年,并使用WebofScience和Scopus来确定引用纳入研究的报告。如果高收入国家调查医院医疗保健专业人员对ABR的看法,则包括定量原始研究的报告。描述性数据和关于原因的感知数据,后果,并提取了关于ABR的解决方案。PROSPERO注册:CRD42022359249。
结果:数据库搜索和引文跟踪分别产生了13,551和694篇论文。来自46项研究的48份报告被纳入审查。这些研究在1999年至2021年之间进行,包括8至1362名参与者。医疗保健专业人员认为ABR是一个在全国范围内比在当地更严重的问题,他们主要认为ABR是一个遥远而抽象的问题。研究大多同意将处方行为作为ABR的原因和解决方案,而外部原因和解决方案(例如,在农业方面)引起的协议较少。
结论:主要关注医疗保健专业人员对ABR的看法的研究是有限的。医疗保健专业人员认为处方行为是ABR的主要原因,也是ABR解决方案的重点领域。
OBJECTIVE: Antibiotic resistance (ABR) is a major threat to public health. Hospital healthcare professionals are important stakeholders in curbing ABR. To be able to encourage healthcare professionals to act against ABR, information on their perceptions is needed. Yet, summary evidence on how healthcare professionals perceive ABR causes, consequences, and solutions is outdated. This review aims to elucidate these perceptions.
METHODS: We searched MEDLINE, EMBASE, PsycINFO, and CINAHL for literature published until July 6th, 2022, and used Web of Science and Scopus to identify reports citing included studies. Reports of quantitative original research from high-income countries were included if they investigated hospital healthcare professionals\' perceptions about ABR. Descriptive data and data on perceptions about causes, consequences, and solutions regarding ABR were extracted. PROSPERO registration: CRD42022359249.
RESULTS: The database search and citation tracking yielded 13,551 and 694 papers respectively. Forty-eight reports from 46 studies were included in the review. These studies were performed between 1999 and 2023 and included between 8 and 1362 participants. Healthcare professionals perceived ABR as a problem that is more severe nationally than locally and they primarily recognize ABR as a distant and abstract problem. Studies mostly concurred on prescribing behavior as a cause and a solution for ABR, while external causes and solutions (e.g., in agriculture) elicited less agreement.
CONCLUSIONS: Studies with a primary focus on the perceptions of healthcare professionals about ABR are limited. Healthcare professionals perceive prescribing behavior as a major cause of ABR and a focus area for ABR solutions.