animal breeding

动物育种
  • 文章类型: Journal Article
    生命周期评估(LCA)量化了环境影响类别的变化(全球变暖,富营养化,等。)从2021年到2030年,由于育种公司Genus-PIC的猪品系(再)生产性状的遗传趋势。根据育种目标中性状的权重和它们之间的遗传协方差,用选择指数理论预测了2030年的水平。对于大多数影响类别,预计每年改善0.9%。另一个LCA根据PIC遗传学与行业平均水平比较了2021年北美生猪生产的影响。软件openLCA将材料和能量流转换为影响框架ReCiPe-2016、PEF-3.1和IPCC-2021的类别。流量来自客户记录的数据(1.1/470万母猪/育肥猪)和第三方数据聚合器的订户(1.3/910万)。对于ReCiPe-2016的13/18类,PEF-3.1的19/25类以及IPCC-2001的所有类别,PIC遗传学的影响比行业平均水平高7-8%。猪育种提供了积极的环境结果,作为对选择以盈利为导向的育种目标的相关反应。这种趋势是添加剂;技术发展将增加它。养殖种群结构和技术的不同投资水平以及养殖企业运营效率的不同,导致生猪生产对环境的影响存在实质性差异。
    Lifecycle assessment (LCA) quantified changes in environmental impact categories (global warming, eutrophication, etc.) from 2021 to 2030 due to genetic trends in (re)production traits in pig lines of the breeding company Genus-PIC. The 2030 levels were projected with selection index theory based on weightings of traits in the breeding goals and genetic covariances among them. The projected improvement was 0.9% annually for most impact categories. Another LCA compared the impacts of 2021 North American pig production based on PIC genetics versus the industry average. Software openLCA converted material and energy flows to impact categories of frameworks ReCiPe-2016, PEF-3.1, and IPCC-2021. Flows came from data recorded by customers (1.1/4.7 million sows/finishing pigs) and by subscribers to a third-party data aggregator (1.3/9.1 million). PIC genetics have a 7-8% better impact than industry average for 13/18 categories of ReCiPe-2016, 19/25 of PEF-3.1, and all categories of IPCC-2001. Pig breeding delivers positive environmental outcomes as correlated responses to selection for profitability-oriented breeding goals. This trend is additive; technology development will increase it. Different investment levels in breeding population structure and technology and different operational efficiencies of breeding companies cause substantial differences in the environmental impact of pig production.
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  • 文章类型: Journal Article
    热休克蛋白(HSP)通过充当分子伴侣在胁迫条件下的所有生物体中发挥重要作用。不同HSP在应激过程中的表达根据其保护功能和抗凋亡活性而变化。HSPs的应用提高了动物育种的效率,降低了经济成本。通过上调HSP的表达,饲料补充剂可以提高农场动物的应激耐受性。此外,HSPs的高表达通常是肿瘤细胞的特征,抑制HSPs的表达是杀死这些细胞和治疗癌症的一种有前途的新方法。在本次审查中,总结了以往关于HSPs在动物育种和兽医学中应用的研究结果,并简要讨论了HSPs在动物中的作用知识。
    Heat shock proteins (HSPs) play an important role in all living organisms under stress conditions by acting as molecular chaperones. The expression of different HSPs during stress varies depending on their protective functions and anti-apoptotic activities. The application of HSPs improves the efficiency and decreases the economic cost of animal breeding. By upregulating the expression of HSPs, feed supplements can improve stress tolerance in farm animals. In addition, high expression of HSPs is often a feature of tumor cells, and inhibiting the expression of HSPs is a promising novel method for killing these cells and treating cancers. In the present review, the findings of previous research on the application of HSPs in animal breeding and veterinary medicine are summarized, and the knowledge of the actions of HSPs in animals is briefly discussed.
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  • 文章类型: Editorial
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    在小规模或大规模生产系统中实施动物育种计划的局限性之一是缺乏生产记录和家谱记录。在这种情况下,分子标记可以帮助获得育种计划的信息。本研究通过分子谱系重建将分子数据纳入传统遗传评估模型,作为随机效应,并通过贝叶斯聚类作为固定效应。方法对表型数据和系谱信息不完整的14只奶山羊群进行了泌乳曲线性状检测。结果表明,原始与MOLCOAN的关系增加了37.3%,并聚类为五个遗传组。数据导致估计加性方差,误差方差,以及四种不同模式的遗传力,包括谱系和分子信息。偏差信息标准(DIC)值表明,包含分子信息的模型具有更大的拟合性,无论是固定(遗传簇)还是随机(分子矩阵)效应。简单标记的分子信息可以补充信息很少的群体中的遗传改良策略。
    One of the limitations of implementing animal breeding programs in small-scale or extensive production systems is the lack of production records and genealogical records. In this context, molecular markers could help to gain information for the breeding program. This study addresses the inclusion of molecular data into traditional genetic evaluation models as a random effect by molecular pedigree reconstruction and as a fixed effect by Bayesian clustering. The methods were tested for lactation curve traits in 14 dairy goat herds with incomplete phenotypic data and pedigree information. The results showed an increment of 37.3% of the relationships regarding the originals with MOLCOAN and clustering into five genetic groups. Data leads to estimating additive variance, error variance, and heritability with four different models, including pedigree and molecular information. Deviance Information Criterion (DIC) values demonstrate a greater fitting of the models that include molecular information either as fixed (genetic clusters) or as random (molecular matrix) effects. The molecular information of simple markers can complement genetic improvement strategies in populations with little information.
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  • 文章类型: Journal Article
    动物育种中的基因组研究提供了广泛的参考;然而,重要的是要注意,基因和mRNA本身并不能完全捕获生物体的复杂性。蛋白质翻译后修饰,这涉及到遗传和环境因素调节的共价修饰,作为调节蛋白质结构的基本表观遗传机制,活动,和功能。在这次审查中,我们全面总结了与动物能量代谢相关的代谢酶的各种磷酸化和酰化修饰,包括乙酰化,琥珀酰化,巴豆酰化,β-羟基丁基化,乙酰乙酰化,和乳酸化。值得注意的是,与人类研究相比,动物能量代谢和修饰调节的研究落后于动物育种对生长发育的需求。因此,这篇综述通过基于人类或动物模型的相关发现,探索未报告的家畜修饰类型,提供了一个新的研究视角。
    Genomic studies in animal breeding have provided a wide range of references; however, it is important to note that genes and mRNA alone do not fully capture the complexity of living organisms. Protein post-translational modification, which involves covalent modifications regulated by genetic and environmental factors, serves as a fundamental epigenetic mechanism that modulates protein structure, activity, and function. In this review, we comprehensively summarize various phosphorylation and acylation modifications on metabolic enzymes relevant to energy metabolism in animals, including acetylation, succinylation, crotonylation, β-hydroxybutylation, acetoacetylation, and lactylation. It is worth noting that research on animal energy metabolism and modification regulation lags behind the demands for growth and development in animal breeding compared to human studies. Therefore, this review provides a novel research perspective by exploring unreported types of modifications in livestock based on relevant findings from human or animal models.
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  • 文章类型: Journal Article
    已经确定椎骨的数量与体型和肉类生产力有关。在当前的研究中,我们利用数字X线摄影(DR)技术来检测活驴的胸腰椎数量。为此,我们首次推出了由我们的团队设计的开创性装置,用于评估胸腰段椎骨数量特征,采用来自五个不同的驴农场的1000头驴样本。这项评估纳入了一系列关键的身体指标,包括身高,长度,和其他各种测量。随后,我们的研究确定了112头驴胸腰椎的数量,利用DR系统。这些发现通过屠宰驴进行的验尸评估得到了进一步验证。我们的发现表明,通过DR系统在活驴中可视化的胸腰椎数量与通过屠宰验证获得的胸腰椎骨数量之间存在显着相似之处。总之,这项研究强调了DR系统检测活体驴胸腰椎的准确性和有效性,这可能有助于评估体型和肉类生产力。我们还建议使用DR系统对其他动物的胸腰椎骨进行计数,这可能是畜牧业的有用补充,用于预测体型和肉类生产率。
    It has been well-established that the number of vertebrae is associated with body size and meat productivity. In current study we utilized a digital radiography (DR) technology to detect the number of thoracolumbar vertebrae in live donkeys. For this purpose, we introduced for the first time a groundbreaking device designed by our team for assessing thoracolumbar vertebrae number traits in equids, employing a sample of 1,000 donkeys sourced from five distinct donkey farms. This assessment incorporates a range of crucial body metrics, including body height, length, and various other measurements. Subsequently, our study determined the number of thoracolumbar vertebrae in 112 donkeys, utilizing the DR system. These findings were further validated through post-mortem evaluations conducted by slaughtering the donkeys. Our findings demonstrated a remarkable resemblance between the thoracolumbar vertebrae numbers visualized through the DR system in live donkeys and those obtained via slaughter verification. In conclusion, this research underscores the accuracy and effectiveness of the DR system for the detection of thoracolumbar vertebrae in live donkeys, which might be helpful for assessing the body size and meat productivity. We also recommended the utilization of DR system for counting thoracolumbar vertebrae in other animals in live state and could be a useful addition to livestock business industry for the prediction of body size and meat productivity efficiency.
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  • 文章类型: Journal Article
    褐藻多糖,一种主要在褐藻中发现的水溶性杂多糖,包含活性组分如岩藻糖和硫酸基团。这种多糖表现出一系列的生理活性,包括抗氧化剂,抗病毒,抗癌,和免疫调节活动。鉴于全球禁止在动物饲料中使用抗生素,人们对识别安全越来越感兴趣,缺乏毒副作用的天然抗生素替代品。本研究重点分析了岩藻依聚糖在畜牧业中的影响,并对岩藻依聚糖的制备方法进行了全面的综述。以及它的物理和化学特性。它在水生物种育种中的应用,牲畜,和家禽也进行了总结。这项研究的目的是建立一个在畜牧业中使用岩藻依聚糖的理论框架,并为动物育种和饲料行业的理论基础做出贡献。
    Fucoidan, a water-soluble heteropolysaccharide predominantly found in brown algae, comprises active components such as fucose and sulfate groups. This polysaccharide exhibits a range of physiological activities, including antioxidant, antiviral, anticancer, and immunomodulatory activities. In light of the global prohibition of antibiotics in animal feed, there is increasing interest in identifying safe, natural antibiotic alternatives that lack toxic side effects. This study focuses on analysing the impact of fucoidan in animal husbandry and provides a comprehensive review of the methods for preparing fucoidan, along with its physical and chemical characteristics. Its applications in the breeding of aquatic species, livestock, and poultry have also been summarized. The aim of this study was to establish a theoretical framework for the use of fucoidan in animal husbandry and to contribute to the theoretical underpinnings of the animal breeding and feed industries.
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  • 文章类型: Journal Article
    这项研究的目的是评估与最佳线性无偏预测(BLUP)方法相比,使用单步基因组最佳线性无偏预测(ssGBLUP)方法合并基因组数据对初生时年龄育种值可靠性的影响。产卵间隔,夏洛莱牛的寿命为78个月。该研究包括48,590名纯种夏洛来人,根据基因分型和表现记录分为四个亚组。结果表明,考虑基因型可显着提高所有类别的基因组估计育种值(GEBV)可靠性,除了非基因型个体。对于年轻的基因型个体,男女的可靠性提高高达27%。对于具有性能记录的经基因分型证明的公牛和奶牛,平均可靠性最高。纳入基因组数据进一步将奶牛和公牛的可靠性提高了22%和21%,分别。可靠性的增加主要是在前三次放生期间观察到的,然后差异减少了。进口个体的估计育种值(EBV)和GEBV可靠性低于国内种群,可能是由于与国内人口的遗传联系薄弱。然而,当进口小母牛的后代被国内公牛饲养时,可靠性提高了24%。对于非基因型个体,仅观察到可靠性略有增加;然而,人群中基因分型个体的数量仍然相对较少。
    The aim of this study was to assess the impact of incorporating genomic data using the single-step genomic best linear unbiased prediction (ssGBLUP) method compared to the best linear unbiased prediction (BLUP) method on the reliability of breeding values for age at first calving, calving interval, and productive longevity at 78 months in Charolais cattle. The study included 48,590 purebred Charolais individuals classified into four subgroups based on genotyping and performance records. The results showed that considering genotypes significantly improved genomic estimated breeding values (GEBV) reliability across all categories except nongenotyped individuals. For young genotyped individuals, the increase in reliability was up to 27% for both sexes. The highest average reliability was achieved for genotyped proven bulls and cows with performance records, and the inclusion of genomic data further improved the reliability by up to 22% and 21% for cows and bulls, respectively. The gain in reliability was observed mainly during the first three calvings, and then the differences decreased. The imported individuals showed lower estimated breeding values (EBV) and GEBV reliabilities than the domestic population, probably due to the weak genetic connection with the domestic population. However, when the progeny of imported heifers were sired by domestic bulls, the reliability increased by up to 24%. For nongenotyped individuals, only a slight increase in reliability was observed; however, the number of genotyped individuals in the population was still relatively small.
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  • 文章类型: Journal Article
    漫长的19世纪是农业和动物生物学许多发展和技术创新的时期,在此期间,行为者试图根据新信息纳入新的做法。到本世纪中叶,然而,虽然遗传稳步成为畜牧业的主导概念,一些与巴西牲畜改良相关的政策似乎是根据法国博物学家乔治·路易斯·勒克莱尔在18世纪中叶建立的气候确定性概念而制定的,布冯伯爵.他的动物退化理论提出,除其他外,反复杂交以保护生活在非本地环境中的动物物种免受气候引起的退化的必要性。尽管在19世纪初基本上名誉扫地,法国博物学家的教导似乎在巴西通过应用自然科学实现国家农业现代化的计划中找到了支持者。在这里,我研究了布冯理论在政府资助的改善畜牧业和育种技术的计划中的复兴,包括该理论在现实世界中的实际应用。最终,我认为,布冯的退化理论被用来调整公共政策和资金,以改善1856年至1860年间巴西的驯养动物。
    The long 19th century was a period of many developments and technical innovations in agriculture and animal biology, during which actors sought to incorporate new practices in light of new information. By the middle of the century, however, while heredity steadily became the dominant concept in animal husbandry, some policies related to livestock improvement in Brazil seemed to have been tailored following a climate-deterministic concept established in the mid-18th century by the French naturalist Georges-Louis Leclerc, the Comte de Buffon. His theory of animal degeneration posited, among other things, the necessity of recurrent crossbreeding to preserve animal species living in nonnative environments from climate-induced degeneration. Although largely discredited by the early 19th century, the teachings of the French naturalist seem to have found supporters in a Brazilian program to modernize national agriculture through the application of the natural sciences. Herein I examine the revival of Buffon\'s theories in that government-sponsored program to improve animal husbandry and breeding techniques, including actual applications of this theory in the real world. Ultimately, I argue that Buffon\'s theory of degeneration was used to tailor public policies and funding for the improvement of domesticated animals in Brazil between 1856 and 1860.
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