背景:在苏丹,关于流行病学的知识有限,甲状腺癌的临床特点和病理类型。为了解决这个缺点,我们研究了临床,国家癌症研究所-Gezira大学(NCI-UG)甲状腺癌的病理和治疗模式,苏丹。
方法:我们对2009年1月至2017年12月接受NCI-UG治疗的甲状腺癌患者进行了一项基于医疗机构的回顾性研究。
结果:在研究期间共发现了139例甲状腺癌患者。肿瘤在女性中更为常见(69%)。甲状腺肿是主要症状(85%)。甲状腺癌最常见的类型是滤泡状癌(41%),其次是乳头状癌(24%),然后是间变性癌(20%)。妇女的平均年龄为56.3岁(SD±14.7),男性为52.5岁(SD±16.6)。阶段I的频率,II,III,IV是17%,22%,16%,45%,分别。79%的病例进行了不同类型的甲状腺切除术,肺叶切除术占4%,17%的人没有手术。只有28%的病例接受了放射性碘。分别对17%和37%的病例进行姑息化疗和放疗,分别。
结论:甲状腺癌在女性中更为普遍,大多数患者出现在晚期。卵泡型的优势表明,该人群中的大多数是缺碘的。
BACKGROUND: In Sudan, there is limited knowledge on the epidemiology, clinical characteristics and pathological patterns of thyroid cancer. To address this shortcoming, we studied the clinical, pathological and treatment patterns of thyroid cancer at the National Cancer Institute ‒ University of Gezira (NCI-UG), Sudan.
METHODS: We performed a retrospective health facility-based study of patients with thyroid cancer who were treated at NCI-UG from January 2009 to December 2017.
RESULTS: A total of 139 patients with thyroid cancer were identified during the study period. Tumors were more common among women (69%). Goiter was the main presenting symptom (85%). The most common type of thyroid cancer was follicular carcinoma (41%), followed by papillary carcinoma (24%), then anaplastic carcinoma (20%). The mean age of the women was 56.3 years (SD ± 14.7), compared to 52.5 years (SD ± 16.6) for the men. The frequencies of stage I, II, III, and IV were 17%, 22%, 16%, and 45%, respectively. Different types of thyroidectomies were performed in 79% of the cases, lobectomy in 4%, and no surgery in 17%. Only 28% of the cases received radioactive iodine. Palliative chemotherapy and radiotherapy were prescribed to 17% and 37% of the cases, respectively.
CONCLUSIONS: Thyroid cancer is more prevalent among women and most patients present at later stages. The dominance of follicular type suggests that the majority of this population is iodine-deficient.