analytical techniques

分析技术
  • 文章类型: Journal Article
    Rechargeable aluminum-ion batteries (AIBs) with organic electrode materials have garnered significant attention due to their excellent safety profile, cost-effectiveness, and eco-friendly nature. This review delves into the intrinsic attributes of organic compounds and their impact on battery performance, mainly focusing on the alteration of ion interactions and charge storage mechanisms at the active sites. The ultimate aim is to propose innovative design approaches for AIBs that overcome the constraints associated with various types of organic materials. The review also discusses the application of advanced analytical tools, providing insights to better understand the electrochemical process of AIBs.
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  • 文章类型: Journal Article
    在快速发展的生命科学和生物医学领域,检测低丰度生物分子,和超弱生物信号提出了重大挑战。这刺激了旨在提高灵敏度和特异性的分析技术的快速发展。这些进步,包括信号放大策略和生物识别事件的整合,标志着生物分析精度和准确性的变革时代。这些创新中一个突出的方法是免疫滚环扩增(免疫RCA)技术,它有效地将免疫测定与通过RCA的信号放大相结合。这个过程开始于一个靶向的生物分子,如蛋白质或细胞,与基质上固定的抗体或探针结合。环状DNA模板的引入触发了RCA,导致指数放大和信号强度显着增强,因此,即使在单分子水平上,靶分子也是可检测和可定量的。本文综述了免疫RCA在生物标志物检测中的生物传感策略和广泛的实际应用。此外,它仔细检查了这些传感器固有的局限性,并提出了对其未来轨迹的期望。这篇综述为在各个领域推进免疫RCA提供了有价值的参考。比如诊断,生物标志物发现,和分子成像。
    In the rapidly evolving field of life sciences and biomedicine, detecting low-abundance biomolecules, and ultraweak biosignals presents significant challenges. This has spurred a rapid development of analytical techniques aiming for increased sensitivity and specificity. These advancements, including signal amplification strategies and the integration of biorecognition events, mark a transformative era in bioanalytical precision and accuracy. A prominent method among these innovations is immuno-rolling circle amplification (immuno-RCA) technology, which effectively combines immunoassays with signal amplification via RCA. This process starts when a targeted biomolecule, such as a protein or cell, binds to an immobilized antibody or probe on a substrate. The introduction of a circular DNA template triggers RCA, leading to exponential amplification and significantly enhanced signal intensity, thus the target molecule is detectable and quantifiable even at the single-molecule level. This review provides an overview of the biosensing strategy and extensive practical applications of immuno-RCA in detecting biomarkers. Furthermore, it scrutinizes the limitations inherent to these sensors and sets forth expectations for their future trajectory. This review serves as a valuable reference for advancing immuno-RCA in various domains, such as diagnostics, biomarker discovery, and molecular imaging.
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  • 文章类型: Journal Article
    基于纸的定点照护(PoC)检测平台应用侧流测定(LFA),由于其易于使用,在诊断领域以及环境应用中获得了最重要的批准。低成本,和快速信号读出。在新冠肺炎实施偏远地区公共卫生快速管理的最后一个全球大流行时代,它集中了自我评估的方面,显示出有希望的潜力。从这个角度来看,本综述的重点是美化LFA的当前框架,并整合组件和特性,以通过提高检测极限来改善测定。这篇综述强调了试验设计的协同方面,样品富集策略,基于新型纳米材料的信号传感器,以及对灵敏度和特异性增强有显著贡献的高端分析技术。讨论了各种最新研究,以支持LFA系统中的创新,这些创新专注于快速PoC测试的准确性和可靠性。审查还全面概述了LFA商业化的所有可能困难,使其适用于病原体监测,水和食物测试,疾病诊断,以及农业和环境问题。
    Paper based point-of-care (PoC) detection platforms applying lateral flow assays (LFAs) have gained paramount approval in the diagnostic domain as well as in environmental applications owing to their ease of utility, low cost, and rapid signal readout. It has centralized the aspect of self-evaluation exhibiting promising potential in the last global pandemic era of Covid-19 implementing rapid management of public health in remote areas. In this perspective, the present review is focused towards landscaping the current framework of LFAs along with integration of components and characteristics for improving the assay by pushing the detection limits. The review highlights the synergistic aspects of assay designing, sample enrichment strategies, novel nanomaterials-based signal transducers, and high-end analytical techniques that contribute significantly towards sensitivity and specificity enhancement. Various recent studies are discussed supporting the innovations in LFA systems that focus upon the accuracy and reliability of rapid PoC testing. The review also provides a comprehensive overview of all the possible difficulties in commercialization of LFAs subjecting its applicability to pathogen surveillance, water and food testing, disease diagnostics, as well as to agriculture and environmental issues.
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  • 文章类型: Journal Article
    生物标记是特定的指标,可用于通过反映独特的特征(如品种或地理来源)来鉴定植物油。生物标志物可以源自植物油本身的主要组分或源自与加工方法或掺假物相关的污染物和痕量物质。该综述强调了在鉴定用于植物油认证的新型生物标志物方面的关键发现。各种分析技术已被证明在区分与特定植物油品种或地理来源相关的独特生物标志物方面是有效的。使用植物油和相关污染物或痕量物质的生物标志物提供了一种全面的认证方法。然而,新型生物标志物的鉴定对于提高食品安全具有巨大的潜力,防止欺诈,维护植物油行业的消费者健康。正在进行的生物标志物鉴定的研究和进步代表了解决植物油中真实性问题的有希望的途径。
    Biomarkers are specific indicators that can be used to authenticate vegetable oils by reflecting unique characteristics such as variety or geographical origin. Biomarkers can originate from the primary components of the vegetable oil itself or from contaminants and trace substances linked to processing methods or adulterants. The review highlights the key findings in the identification of novel biomarkers for vegetable oil authentication. Various analytical techniques have proven effective in distinguishing unique biomarkers associated with specific vegetable oil varieties or geographical origins. The use of biomarkers of vegetable oils and associated contaminants or trace substances offers a comprehensive approach to authentication. However, the identification of novel biomarkers holds immense potential for enhancing food safety, preventing fraud, and safeguarding consumer health in the vegetable oil industry. The ongoing research and advancements in biomarker identification represent a promising avenue for addressing authenticity concerns in vegetable oils.
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  • 文章类型: Journal Article
    微塑料(MPs)代表了广泛分布在各种环境中的大量新兴污染物。引发了人们对其环境影响的日益关注。在环境系统中,溶解有机物(DOM)在塑造物理过程中至关重要,化学,和污染物的生物过程,同时对全球碳预算做出了重大贡献。最近的发现表明,微塑料衍生的溶解有机物(MP-DOM)约占海洋表面DOM的10%。引起相当大的注意。因此,这项研究的主要目的是探索,一代,表征,和MP-DOM的环境行为。MP-DOM的形成和特征受MP的浸出条件和类型的深刻影响。这篇综述深入研究了MP-DOM的生成机制,并概述了各种分析技术,包括紫外可见(UV-Vis)光谱,荧光光谱法,傅里叶变换红外光谱(FTIR),和质谱,用于评估MP-DOM特征。此外,这篇综述调查了MP-DOM的环境行为,包括它对生物体的影响,光化学过程,消毒副产物(DBPs)的形成,吸附行为,以及它与自然DOM的相互作用。最后,这篇综述概述了研究挑战,对未来MP-DOM研究的展望,以及相关的环境影响。
    Microplastics (MPs) represent a substantial and emerging class of pollutants distributed widely in various environments, sparking growing concerns about their environmental impact. In environmental systems, dissolved organic matter (DOM) is crucial in shaping the physical, chemical, and biological processes of pollutants while significantly contributing to the global carbon budget. Recent findings have revealed that microplastic-derived dissolved organic matter (MP-DOM) constitutes approximately 10 % of the DOM present on the ocean surface, drawing considerable attention. Hence, this study\'s primary objective is to explore, the generation, characterization, and environmental behaviors of MP-DOM. The formation and characteristics of MP-DOM are profoundly influenced by leaching conditions and types of MPs. This review delves into the mechanisms of the generation of MP-DOM and provides an overview of a wide array of analytical techniques, including ultraviolet-visible (UV-Vis) spectroscopy, fluorescence spectroscopy, Fourier transform infrared spectroscopy (FTIR), and mass spectroscopy, used to assess the MP-DOM characteristics. Furthermore, this review investigates the environmental behaviors of MP-DOM, including its impacts on organisms, photochemical processes, the formation of disinfection by-products (DBPs), adsorption behavior, and its interaction with natural DOM. Finally, the review outlines research challenges, perspectives for future MP-DOM research, and the associated environmental implications.
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  • 文章类型: Journal Article
    这篇综述的主要目的是广泛总结新兴研究领域的最新进展,重点是检测重金属离子污染,特别是传感策略。这篇综述探讨了各种重金属离子检测方法,包括光谱学,电化学方法,和光学技术。为了应对对快速,敏感,和选择性传感器。值得注意的是,荧光传感器由于突出的特异性等众多优点而获得了突出的地位,可逆性,和敏感性。Further,它还探讨了各种纳米材料用于检测重金属离子的讨论。在这方面,独家重点放在基于有机染料的荧光纳米材料上,量子点,和用于从水性系统中去除金属离子的荧光传感器,以识别清洁环境中危险重金属离子的命运。
    The main aim of this review is to provide a holistic summary of the latest advances within the research area focusing on the detection of heavy metal ion pollution, particularly the sensing strategies. The review explores various heavy metal ion detection approaches, encompassing spectrometry, electrochemical methods, and optical techniques. Numerous initiatives have been undertaken in recent times in response to the increasing demand for fast, sensitive, and selective sensors. Notably, fluorescent sensors have acquired prominence owing to the numerous advantages such as good specificity, reversibility, and sensitivity. Further, this review also explores the advantages of various nanomaterials employed in sensing heavy metal ions. In this regard, exclusive emphasis is placed on fluorescent nanomaterials based on organic dyes, quantum dots, and fluorescent aptasensors for metal ion removal from aqueous systems, and to identify the fate of heavy metal ions in the natural environment.
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  • 文章类型: Journal Article
    这篇全面的综述提供了切削液的化学分析,深入研究它们的配方和去配方过程。这项研究涵盖了广泛的切削液配方,从主要包含油的简单组合物,无论是矿物质还是蔬菜,乳液。后者涉及表面活性剂的整合,包括非离子和阴离子类型,以及各种各样的添加剂。关于油,由于环境原因,目前的趋势倾向于使用植物油代替矿物油。由于植物油更容易氧化,化学变化,抗氧化剂的添加可能是必要的。对不同化合物的化学方面进行了审查,为了了解各组分的作用及其对流体润滑的影响,冷却,抗磨损,和防腐性能。此外,该评论探讨了用于解剖切削液的去配方方法。该方法包括两步法:通过物理或化学处理分离乳液的水相和有机相,并随后对每种化合物进行详细分析以鉴定化合物。几种分析技术,包括光谱或色谱,可以同时用于揭示样品的化学结构。这篇综述旨在为改善切削液产生的废物处理做出贡献。通过收集有关配方的广泛信息,去配方,和成分的化学成分,有可能有效地加强废物管理和处置。
    This comprehensive review offers a chemical analysis of cutting fluids, delving into both their formulation and deformulation processes. The study covers a wide spectrum of cutting fluid formulations, ranging from simple compositions predominantly comprising oils, whether mineral or vegetable, to emulsions. The latter involves the integration of surfactants, encompassing both nonionic and anionic types, along with a diverse array of additives. Concerning oils, the current trend leans towards the use of vegetable oils instead of mineral oils for environmental reasons. As vegetable oils are more prone to oxidation, chemical alterations, the addition of antioxidant may be necessary. The chemical aspects of the different compounds are scrutinized, in order to understand the role of each component and its impact on the fluid\'s lubricating, cooling, anti-wear, and anti-corrosion properties. Furthermore, the review explores the deformulation methodologies employed to dissect cutting fluids. This process involves a two-step approach: separating the aqueous and organic phases of the emulsions by physical or chemical treatments, and subsequently conducting a detailed analysis of each to identify the compounds. Several analytical techniques, including spectrometric or chromatographic, can be employed simultaneously to reveal the chemical structures of samples. This review aims to contribute to the improvement of waste treatment stemming from cutting fluids. By gathering extensive information about the formulation, deformulation, and chemistry of the ingredients, there is a potential to enhance the waste management and disposal effectively.
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  • 文章类型: Journal Article
    花青素(ANCs)是从蓝莓等色素食品中获得的,草莓,和红卷心菜,是属于类黄酮家族的酚类化合物。近年来,ANCs因其多样化的生物活性和潜在的健康益处而受到广泛关注。这篇全面的综述提出了花青素的整体探索,从它们的化学结构和生物合成途径到用于鉴定和定量的无数分析技术。此外,植物来源丰富的挂毯产量花青素被深入研究,突出了它们在各种药物制剂中的掺入。这篇综述旨在提供关于花青素的现有知识的全面综合,从它们的起源到它们多方面的药理活动和创新的药物应用。

    Anthocyanins (ANCs) are obtained from pigmented foods like blueberry, strawberry, and red cabbage and are phenolic compounds belonging to the flavonoids family. ANCs have garnered significant attention in recent years due to their diverse biological activities and potential health benefits. This comprehensive review presents a holistic exploration of anthocyanins, spanning from their chemical structure and biosynthesis pathways to the myriad analytical techniques employed for their identification and quantification. Furthermore, the rich tapestry of plant sources yields anthocyanins is delved into, highlighting their incorporation into various pharmaceutical formulations. This review aims to provide a comprehensive synthesis of current knowledge on anthocyanins, spanning from their origins in nature to their multifaceted pharmacological activities and innovative pharmaceutical applications.

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  • 文章类型: Journal Article
    兽药是当代畜牧业和粮食生产所必需的,但是它们的残留物会滞留在从动物获得的食物中,并对人类构成危险。在这次审查中,我们的目标是突出来源,发生,人类暴露途径,食用动物产品中药物残留对人体健康的影响。在使用兽药之后,被称为药物残留的药理活性化合物可以在食品中发现,环境,或动物。它们会给人们带来重大的健康问题,包括抗生素耐药性的发展,癌症的发展,致畸作用,超敏反应,和正常肠道菌群的破坏。动物产品中的药物残留可以来源于多种来源,包括水或食物污染,标签外用药,而忽略停药期。这篇综述还研究了人类如何通过饮用水暴露于药物残留,食物,空气,和灰尘,并讨论了识别食品中这些残留物的各种分析技术。此外,我们提出了一些潜在的解决方案,以防止或减少动物产品和人类接触途径中的药物残留,例如实施提款期,监控程序,教育运动,以及对保障公众健康至关重要的新技术。这项审查强调了解决兽药残留作为重大和新兴的公共卫生威胁的紧迫性,呼吁研究人员共同努力,政策制定者,和行业利益相关者制定可持续的解决方案,以确保全球食品供应链的安全。
    Veterinary medications are necessary for both contemporary animal husbandry and food production, but their residues can linger in foods obtained from animals and pose a dangerous human risk. In this review, we aim to highlight the sources, occurrence, human exposure pathways, and human health effects of drug residues in food-animal products. Following the usage of veterinary medications, pharmacologically active compounds known as drug residues can be found in food, the environment, or animals. They can cause major health concerns to people, including antibiotic resistance development, the development of cancer, teratogenic effects, hypersensitivity, and disruption of normal intestinal flora. Drug residues in animal products can originate from variety of sources, including water or food contamination, extra-label drug use, and ignoring drug withdrawal periods. This review also examines how humans can be exposed to drug residues through drinking water, food, air, and dust, and discusses various analytical techniques for identifying these residues in food. Furthermore, we suggest some potential solutions to prevent or reduce drug residues in animal products and human exposure pathways, such as implementing withdrawal periods, monitoring programs, education campaigns, and new technologies that are crucial for safeguarding public health. This review underscores the urgency of addressing veterinary drug residues as a significant and emerging public health threat, calling for collaborative efforts from researchers, policymakers, and industry stakeholders to develop sustainable solutions that ensure the safety of the global food supply chain.
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  • 文章类型: Journal Article
    注入大麻的食物是注入大麻提取物的食品。这些食物包括烘焙食品,糖果,和饮料,提供另一种方式来消费大麻,而不是吸烟或蒸发。确保准确检测注入大麻的食物和识别任何污染物对于公共健康和安全至关重要。这对于遵守法律法规尤为重要,因为这些物质可能具有重大的精神活性作用,特别是对毫无戒心的消费者,如儿童或患有某些疾病的个人。采用高效的提取方法可以大大提高检测精度,确保正确测量食物中大麻素的浓度,并遵守剂量准则和法律限制。这篇综述全面考察了大麻素食品的制备和提取技术。它涵盖了固相萃取等方法,增强基质去除-脂质,Quechers,溶解和分散技术,液相萃取,和其他新兴的方法以及大麻素分析的分析技术。用于测定大麻素的主要分析技术包括液相色谱(LC),气相色谱(GC),实时直接分析(DART),和质谱(MS)。这些提取和分析技术的应用通过它们在分析特定可食用样品中的应用得到了进一步证明,包括油,糖果,饮料,固体咖啡和茶,小吃,宠物食品,和受污染的产品。
    Cannabis-infused edibles are food products infused with a cannabis extract. These edibles include baked goods, candies, and beverages, offering an alternative way to consume cannabis instead of smoking or vaporizing it. Ensuring the accurate detection of cannabis-infused edibles and identification of any contaminants is crucial for public health and safety. This is particularly important for compliance with legal regulations as these substances can have significant psychoactive effects, especially on unsuspecting consumers such as children or individuals with certain medical conditions. Using efficient extraction methods can greatly improve detection accuracy, ensuring that the concentration of cannabinoids in edibles is measured correctly and adheres to dosage guidelines and legal limits. This review comprehensively examines the preparation and extraction techniques for cannabinoid edibles. It covers methods such as solid-phase extraction, enhanced matrix removal-lipid, QuEChERS, dissolution and dispersion techniques, liquid-phase extraction, and other emerging methodologies along with analytical techniques for cannabinoid analysis. The main analytical techniques employed for the determination of cannabinoids include liquid chromatography (LC), gas chromatography (GC), direct analysis in real time (DART), and mass spectrometry (MS). The application of these extraction and analytical techniques is further demonstrated through their use in analyzing specific edible samples, including oils, candies, beverages, solid coffee and tea, snacks, pet food, and contaminated products.
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