背景:成人的注意缺陷多动障碍(ADHD)经常由于伴随的精神疾病而被诊断不足,包括抑郁症状,这可以决定不适当的治疗。我们的研究旨在临床上表征有或没有抑郁症状的成人ADHD,以确定与特定情感气质特征和应对策略的关系。
方法:自2019年9月以来,共有225名连续进入我们的门诊成人多动症服务的门诊患者进行了回顾性筛选,并进行了贝克抑郁量表-II(BDI-II)。孟菲斯经历问题清单(COPE-NV)和气质评估的应对方向,比萨,巴黎和圣地亚哥(TEMPS-M)。
结果:64.7%的患者表现出明显的共病抑郁症状。根据多元线性回归模型,TEMPS-M循环胸腺子量表(B=0.567,p=0.004)和COPE-NVI“积极态度”子量表(B=-0.438,p=0.024)(R=0.496,R2=0.246,F(2,66)=10.747,p<0.001)。
结论:在考虑结果时,应考虑到:评估仅在基线进行,我们的样本仅由成年多动症患者组成,并且大部分没有先前的多动症诊断,多动症亚型发病率之间存在差异,没有健康对照组和情绪失调没有直接评估.
结论:情感气质特征和应对策略可以帮助成人多动症合并抑郁症状患者的临床特征和个性化治疗。有必要进行进一步的研究,以探索该ADHD子样本中靶向心理治疗和药物干预的功效。
BACKGROUND: Attention deficit hyperactivity disorder (
ADHD) in adults could be frequently underdiagnosed due to concomitant psychiatric disorders, including depressive symptomatology, which could determine inappropriate treatments. Our study aims at clinically characterizing adult
ADHD with or without depressive symptomatology in order to identify the relationship with specific affective temperamental profiles and coping strategies.
METHODS: A total of 225 outpatients consecutively afferent to our outpatient adult
ADHD service since September 2019 were retrospectively screened for eligibility and administered Beck Depression Inventory-II (BDI-II), Coping Orientation to Problems Experienced Inventory (COPE-NV) and Temperament Evaluation of the Memphis, Pisa, Paris and San Diego (TEMPS-M).
RESULTS: 64.7 % of patients displayed a significant comorbid depressive symptomatology. According to the multivariate linear regression model, depressive levels were positively predicted by TEMPS-M cyclothymic subscale (B = 0.567, p = 0.004) and negatively predicted by COPE-NVI \"positive attitude\" subscale (B = -0.438, p = 0.024) (R = 0.496, R2 = 0.246, F(2,66) = 10.747, p < 0.001).
CONCLUSIONS: While considering the results, it should be taken in consideration that: the assessment was carried out only at baseline, our sample is constituted only by adult ADHD patients and mostly without a previous
ADHD diagnosis, the presence of a discrepancy between the rates of
ADHD subtypes, the absence of a healthy control group and emotional dysregulation was not directly assessed.
CONCLUSIONS: Affective temperamental profiles and coping strategies could help in clinically characterizing and personalizing treatment in adult comorbid ADHD-depressive symptomatology patients. Further research is warranted to explore the efficacy of targeted psychotherapeutic and pharmacological interventions within this ADHD sub-sample.