背景:腺瘤样牙源性肿瘤(AOT)是起源于牙层或其残留物的良性病变。它是一种相对罕见的肿瘤,约占所有牙源性肿瘤的3%。这项研究的目的是检查尼日利亚五个主要三级中心的AOT的临床和放射学特征。
方法:访问了尼日利亚五个三级医疗机构的存档医院数据存储。检索病例文件和活检记录以获取相关信息。根据标准化形式收集数据,并使用SPSSforWindows(版本20.0;SPSSInc.Chicago,IL).
结果:记录了61例(4.5%)AOT病例。年龄范围为8-46岁,平均年龄为20.4±9.9岁。男性:女性比例为1:1.3。前上颌骨有34例(55.8%),前下颌骨有20例(32.8%)。40例(65.6%)卵泡,发现20例(32.8%)卵泡外病例和1例(1.6%)骨外病例。患牙31例(61.1%),上犬齿累及19例(57.6%)。
结论:这项研究表明AOT在上颌骨更为常见,更多的女性,通常与受影响的犬科动物有关,然而,在这项研究中没有观察到AOT是“三分之二肿瘤”的暗示。
BACKGROUND: Adenomatoid odontogenic tumor (AOT) is a benign lesion originating from the dental lamina or its remnants. It is a relatively uncommon neoplasm representing about 3% of all odontogenic tumors. The aim of this study was to examine the clinical and radiological characteristics of AOTs in five major tertiary centres in Nigeria.
METHODS: Archival hospital-based data stores of five tertiary health facilities in Nigeria were accessed. Case files and biopsy records were retrieved to obtain relevant information. Data was collected according to a proforma for standardization and entered into and analysed using SPSS for Windows (version 20.0; SPSS Inc. Chicago, IL).
RESULTS: 61 (4.5%) cases of AOT were documented. The age range was 8-46 years with a mean age of 20.4±9.9 years. Male: Female ratio was 1:1.3. The anterior maxilla had 34 (55.8%) cases and the anterior mandible had 20 (32.8%) cases. 40 (65.6%) follicular cases, 20 (32.8%) extra-follicular cases and 1(1.6%) extra-osseous case were found. 31 cases (61.1%) were associated with impacted teeth and the upper canine was involved in 19 (57.6%) cases.
CONCLUSIONS: This study showed AOT to be more common in the maxilla, more in females, most often associated with impacted canines, however, the suggestion of AOT being a \"Two third tumour\" was not observed in this study.