Abstract：
Adenoid ameloblastoma (AA) was recently recognised as a separate tumour type in the most recent World Health Organisation (WHO) classification of head and neck tumours. This decision has been considered controversial by several groups, who have described AA as a subtype of ameloblastoma, a hybrid odontogenic tumour or to fall within the spectrum of other recognised odontogenic tumours, including dentinogenic ghost cell tumour and adenomatoid odontogenic tumour. Here we review the reasons for the WHO decision to classify AA as a separate tumour type. We also critique molecular and histological findings from recent reports published since the WHO classification. While acknowledging that the classification of tumours is constantly evolving, the balance of current evidence suggests that AA should remain a distinct tumour type, and not a subtype of ameloblastoma, pending further molecular characterisation.
摘要：
最近，在世界卫生组织（WHO）对头颈部肿瘤的最新分类中，腺样体成釉细胞瘤（AA）被认为是一种单独的肿瘤类型。这个决定被几个团体认为是有争议的，他们将AA描述为成釉细胞瘤的一种亚型，杂合牙源性肿瘤或属于其他公认的牙源性肿瘤，包括牙源性鬼细胞瘤和腺瘤样牙源性肿瘤。在这里，我们回顾了WHO决定将AA分类为单独肿瘤类型的原因。我们还批评了自WHO分类以来发表的最新报告的分子和组织学发现。虽然承认肿瘤的分类在不断发展，当前证据的平衡表明AA应该仍然是一种独特的肿瘤类型，而不是成釉细胞瘤的亚型,等待进一步的分子表征。
