背景:使用不同翻转角演化(SPACE)的应用优化对比度的对比后T1采样完美是评估脑转移的首选3DT1自旋回波序列,无论延长的扫描时间。
目的:评估加速对比后T1-SPACE与迭代去噪(ID)在肿瘤患者颅内增强病变中的应用。
方法:对于颅内病变的评估,108例患者在相同的成像过程中接受了标准和加速T1-SPACE。两名神经放射科医生评估了整体图像质量,神器,增强程度,平均对比度-噪声比/薄壁组织,以及无ID的标准和加速T1-SPACE的增强病变数量。
结果:尽管没有ID的标准和加速的T1-SPACE与有和没有ID的加速SPACE在整体图像质量和平均对比度噪声比/薄壁组织方面存在显著差异,标准和加速T1-SPACE与ID之间没有显着差异。加速的T1-SPACE比标准的T1-SPACE表现出更多的伪影;然而,带ID的加速T1-SPACE显示出比不带ID的加速T1-SPACE明显更少的伪影。无ID的加速T1-SPACE显示的增强病变数量明显低于有ID的标准和加速T1-SPACE;然而,标准T1-SPACE和加速T1-SPACE与ID之间没有显着差异,无论病变大小。
结论:虽然T1-SPACE加速显著缩短了扫描时间,与标准T1-SPACE相比,它显示出更低的整体图像质量和病变可检测性.将ID应用于加速的T1-SPACE可产生与标准T1-SPACE相当的整体图像质量和脑实质中增强病变的检测。具有ID的加速T1-SPACE可能是标准T1-SPACE的有希望的替代品。
BACKGROUND: Post-contrast T1-Sampling Perfection with Application-optimized Contrasts using different flip angle Evolutions (SPACE) is the preferred 3D T1 spin-echo sequence for evaluating brain metastases, regardless of the prolonged scan time.
OBJECTIVE: To evaluate the application of accelerated post-contrast T1-SPACE with iterative denoising (ID) for intracranial enhancing lesions in oncologic patients.
METHODS: For evaluation of intracranial lesions, 108 patients underwent standard and accelerated T1-SPACE during the same imaging session. Two neuroradiologists evaluated the overall image quality, artifacts, degree of enhancement, mean contrast-to-noise ratiolesion/parenchyma, and number of enhancing lesions for standard and accelerated T1-SPACE without ID.
RESULTS: Although there was a significant difference in the overall image quality and mean contrast-to-noise ratiolesion/parenchyma between standard and accelerated T1-SPACE without ID and accelerated SPACE with and without ID, there was no significant difference between standard and
accelerated T1-SPACE with ID.
Accelerated T1-SPACE showed more artifacts than standard T1-SPACE; however,
accelerated T1-SPACE with ID showed significantly fewer artifacts than
accelerated T1-SPACE without ID. Accelerated T1-SPACE without ID showed a significantly lower number of enhancing lesions than standard- and accelerated T1-SPACE with ID; however, there was no significant difference between standard and
accelerated T1-SPACE with ID, regardless of lesion size.
CONCLUSIONS: Although accelerated T1-SPACE markedly decreased the scan time, it showed lower overall image quality and lesion detectability than the standard T1-SPACE. Application of ID to accelerated T1-SPACE resulted in comparable overall image quality and detection of enhancing lesions in brain parenchyma as standard T1-SPACE.
Accelerated T1-SPACE with ID may be a promising replacement for standard T1-SPACE.